Enhanced scavenging of a minor component from mixtures of two immiscible liquids by hollow polymer microgels

Hollow soft nanoparticles are known to be highly perspective containers with high absorption capacity of various substances. In particular, this feature can be applied in terms of solvents separation on...

Cubosomes as Potential Nanocarrier for Drug Delivery: A Comprehensive Review

Lyotropic liquid crystalline cores are characterized as soft nanoparticles and referred as cubosomes. They are prepared to activate the natural self-assembly capability of lipids (e.g., monoolein or phytantriol) in water. Cubosomes are crystalline isotropic lipidic nanoparticles stabilized by Poloxamers such as F127, F108. It is made up of a network of two separate aqueous channels formed by a three-dimensional, non-intersecting lipid bilayer imposed over an indefinite periodic minimum surface of cubic symmetry. Cubosomes constitute unique features such as their special cubic structure which permits to incorporate highly lipophilic, hydrophilic, and amphiphilic drugs. Also, the lipids excipients used in the preparation of cubosomes such as monoolein, phytantriol are biodegradable and biocompatible so these cubic nanoparticles are referred as safe carrier for drug delivery. Cubic lipid nanoparticles have a highly stable cubic shape that allows for a slower rate of dissociation, improved drug retention, and site-specific drug delivery. The architecture of cubic particles provides suitability in the drug delivery as compared to other lipids-based drug delivery systems such as solid lipid nanoparticles (SLN), liposomes due to their drug expulsion to the surface of nanoparticles. Cubosomes with these loaded features/architectural composition led to an array of desired performance. Solvent evaporation, ultrasonication, hydrotrope, spray drying, melt dispersion emulsifying methods are used to prepare these carrier systems.

Hybrid Phosphorus-viologen-dendrimers as new soft nanoparticles. Design and properties.

Various dendritic structures were prepared during the last decades and their properties emphasized in a number of reviews. Among these macromolecular structures, those incorporating phosphorus units – phosphorus dendrimers –...

Interplay between inter- and intraparticle interactions in bi-magnetic core/shell nanoparticles

The synthesis strategy and magnetic characterisation of two systems consisting of nanoparticles with core/shell morphology are presented: an assembly of hard/soft nanoparticles with cores consisting of magnetically hard cobalt ferrite...

Evidence of protein coronas around soft nanoparticles regardless of the chemical nature of the outer surface: structural features and biological consequences

The presence of thick protein coronas has been found around pH-responsive polymeric assemblies. They reduce the levels of cellular uptake, nevertheless with positive outputs with regard to cytotoxic effects.