Cancer attrition immunotherapy

Cancer is a deadly disease wherein the immune system is inefficient, resulting in malignant tumors that metastasize. An active and robust immune system is the body’s natural defense. Research efforts continue exploring alternative immunotherapies to fight cancer. This communication proposes non-infectious vaccines and hyper-allergenic skin creams to starve malignant tumors through immune metabolic interference.

Wireless Sensor Network (WSN) Configuration Method to Increase Node Energy Efficiency through Clustering and Location Information

Wireless Sensor Network (WSN) technology, for services that are difficult to access or which need to be continuously monitored regardless of location, needs further research and development due to an expansion of fields where it can be applied and due to increases in efficiency. In particular, in the field of defense, research on the latest IT technologies including sensor networks is being actively conducted as an alternative to the risky use of personnel in areas such as surveillance and surveillance reconnaissance. This paper experimented with analyzing the conditions necessary for increasing the energy efficiency of the nodes constituting a sensor network using a clustering routing technique and a location-based routing technique. The derived factors include a method for selecting a cluster head (CH), a method for establishing a path from each channel to a base station (BS), and a method for transmitting collected data. We experimented with the derived factors and proposed a WSN configuration method that increases the energy efficiency of each node by applying optimal results and methods that were verified experimentally.

Closing the Gaps in US Rocket Propellant Production, 1940–1945

The article supplements and revises past historiographical explanations on why the US entered World War ii without propellant based engines, for tactical rockets and how that gap was overcome. Short range rockets were used extensively by all sides in the War for various purposes, but in the interwar period (1919–1939), rocket advances were made mostly in Europe with the US lagging behind. The rockets engines were based on solid propellant tubes, but in 1940 there was hardly any US tubes design knowledge and no production facilities. Technological and production gaps had to be closed, and from 1940 were made with a significant help from Britain and under the leadership of the civilian National Defense Research Council (ndrc) agency, merged in 1941 into the Office of Scientific Research and Development (osrd). Due to the pressing needs to equip American forces with rockets, a joint group of ndrc and Army developers modified in early 1942 an existing gun propellant production technology for rocket tubes. Used initially for the Bazooka this adoption was found later to be extremely problematic in production and performance of tubes in the widely-used, Army’s 4.5-inch barrage and fighter plane rockets. Working in parallel, a joint group of ndrc and navy developers was able to construct the more modern tube production process already used abroad, avoiding the main army difficulties and taking the lead. The growing needs for these superior Navy rockets, some of which were used extensively by the Army, led to gaps between supplies and demands by 1943. Two fortunate events, one of them connected with the Soviet Union, helped to relieve the shortage.

Introduction to Special Issue: New Developments in Public Defense Research

This special issue focuses on interdisciplinary research in public defense. Seven papers represent a diverse group of scholars in an understudied field. Two overarching themes emerge. The first theme, “System Interventions: Evaluating Programs and Identifying Opportunities,” includes three studies of innovative policies and practices. Two evaluate new resource injections that support, respectively, social work-initiated holistic defense and counsel at first appearance. The third examines state sentencing schemes to identify opportunities for emphasizing defendant assets instead of deficits. The second theme, “Understanding Decision Makers,” includes four papers drawing on qualitative data regarding juvenile resentencing and reentry, defendant views of attorney–client communication, defender motivations for remaining in the profession, and manager perspectives on likely effects of caseload reductions. As a collection, these papers bridge gaps between theory and practice, offer new insight into public defense as a critical component of criminal legal systems, and identify new avenues for future research.