Concept of Fatty liver and its management in Ayurveda

Fatty liver disease is a most common liver disease affecting a wide range of population worldwide. It is caused due to excessive fat accumulation in liver cells resulting in inflammation in liver. There are various symptoms such as confusion, fatigue, weakness etc. Over-eating is the major lifestyle factor causing fatty liver disease. Alcoholic intake results in alcoholic fatty liver disease Ajirna (indigestion), Sthaulya (obesity) and Prameha (diabetes mellitus) which occurs due to the vitiation of Annavaha, Rasavaha and Medovaha Srotas acts as Nidanarthakara Rogas (diseases which cause another diseases) which may result in the manifestation of non-alcoholic fatty liver. According to Ayurvedic texts, Panchkarma (Virechana) and herbs like Bhumiamalaki and Guduchi etc. acts a hepatoprotective and improves the functioning of liver.

Fibromyalgia patients features in the COVID-19 pandemic in Iraq

Background: Early articles on the impaction of the COVID-19 pandemic found persistent related aggressiveness of fibromyalgia in the general population. Methods: A surveillance study about 100 patients suffering from fibromyalgia in Abu-Graib General Hospital, Baghdad during period from June 2020 to March 2021. The target population for were adults, aged 18 years and older, diagnosed with FM for at least one year and no other pain condition. Data including: age, gender, ethnicity, residence, marital status, BMI, and medical history. Results: Approximately, 100 patients completed ≥ 90% of the surveys and their data were analyzed. Females were 70% whereas males constituted 30% of the sample. Above 50 years was the age of the majority of patients. The mean age was 50.7±12.88 years. White color patients were documented in 92%. Smoker patients were 60%. About 29% of patients were alcoholic intake. Approximately, 49% of patients were obese. Comorbidities were recorded in 62% of patients. In relation to morbidity of persons, myocardial infarction reported in 3%, 7% heart diseases, 4% stroke, 10% liver diseases, 1% renal failure, 26% hypertension, 24% diabetes mellitus, 2% chronic obstructive pulmonary diseases, 9% tuberculosis, 8% bronchial asthma, 6% rheumatoid arthritis, 4% peptic ulcer, 2% systemic lupus arthromatus, 7% migraine, 31% cancers, 2% psychological diseases, and 4% depression. Patients with fibromyalgia described different pattern of symptoms including: Anxiety (54%), depression (50%), insomnia (65%), memory loss (34%), fatigue (94%), pain (92%), and arthralgia (83%). Conclusion: Persons with a fibromyalgia diagnosis had high levels of self-reported pain, non-pain symptoms, comorbidity and psychological distress. Fibromyalgia diagnosis was associated with gender, education, ethnicity, citizenship and unhealthy behaviors.

UMBI UBI JALAR UNGU BALI (Ipomoea batatas) DI TRANSAMINASE SERUM, MALONDIALDEHIDE HEPAR DAN ALKOHOL KRONIS

Oxidative stress as a consequence of chronic alcoholic intake causes lesions of liver tissue. The objective of this study was to identifythe antioxidant effect of ethanol extract derived from Balinese purple sweet potato on the liver tissue in mice after chronic consumptionof alcohol. Subjects of this study were 32 adults male Swiss mice (12–14 weeks) divided into 4 groups with control group post-testonly design. Post-treatment of blood and liver samples were collected from each group of 8 mice. The MDA liver was quantified withthiobarbituric acid reactive substances (TBARS) method. Samples were collected from control group of 8 mice without sweet potatoextract and alcohol, 8 mice with 1 mg extract of Balinese purple sweet potato, 8 mice with 0.8 gram alcohol, and 8 mice with combineof alcohol and extract of Balinese purple sweet potato, each treatment was carried out every day for 4 weeks. The results showed asignificant increase of serum SGOT, SGPT and liver MDA level, after chronic consumption of alcohol (p = 0.00). The decrease of serumSGOT, SGPT and liver level MDA was significant in the group with extract of Balinese purple sweet potato (p = 0.00). The researchersconcluded that the extract of Balinese purple sweet potato had an antioxidant effect in mice which consumed alcohol chronically. Basedon this study it is concluded that extract of Balinese purple sweet potato has a protective effect on the liver cell in mice which consumedalcohol chronically.

The influence of selected environmental factors on the time of natural menopause in women living in the Małopolskie voivodeship

The main objective of the study is to determine which of the chosen environmental factors and selected groups of such factors alter the time of natural menopause in women living in the Małopolska region. Two hundred and thirty two women aged over 40 years were investigated in a cross-sectional survey in Cracow and the surrounding area. Among them 165 women who had undergone natural menopause and had their last bleeding at least 12 month prior to the interview were chosen. To estimate the age at menopause, a retrospective method was used. Univariate and multivariate methods were employed to estimate association of age at natural menopause with factors of interest. Mean age at natural menopause was 50.32 years (SD=3.82). Among biological and socio-economic factors, only the length of the reproductive period (H=106.07; p=0.000) and the age at the time of the first birth (R=0.18; p=0.020) turned out to be associated with the age at natural menopause in the studied group. The length of the smoking period (R=-0.17; p=0.031), the amount (F=3.25; p=0.04) and frequency of alcohol consumed (H=6.95; p=0.031) were the environmental factors related to the time of menopause. Women who drank more and smoked over longer period of time were likely to experience menopause earlier than their less drinking and shorter smoked counterparts. Three factors taken together, frequency of smoking, alcoholic intake and the age the tobacco addiction started (F=3.87; p=0.050), as well as the consumption of strong alcoholic drinks and the early start of tobacco addiction (F=2.85; p=0.026) were significantly related to the occurrence of natural menopause