scholarly journals Factors associated with oral cavity cancers in Sub-Saharan Africa: Summary of the literature

2021 ◽  
Vol 1 (2) ◽  
pp. 34-41
Author(s):  
A Dieng ◽  
AD Faye ◽  
MM Ndiaye ◽  
G Diop ◽  
A Bouazé ◽  
...  
Keyword(s):  
Oral Cavity ◽  
Public Health Problem ◽  
Epidemiological Data ◽  
Sub Saharan Africa ◽  
Factors Associated ◽  
Manual Search ◽  
African Populations ◽  
Localization Strategy ◽  
Sub Saharan ◽  
Oral Cavity Cancers

INTRODUCTION: Oral cavity cancers are now a public health problem according to WHO epidemiological data. There are several risk factors or factors associated with cancers of the oral cavity but they vary according to geographic regions. OBJECTIVE: The objective of this study was to identify factors associated with cancers of the oral cavity in Sub-Saharan African populations through a systematic literature review. METHODOLOGY: Using the data available for the period from January 1980 to December 2019, a synthesis of the literature was carried out. The literature localization strategy included an electronic search of the MEDLINE, EMBASE and GOOGLE SCHOLAR databases from 1980 to 2019 and a manual search of the list of references of articles identified by snowballing. The data were extracted independently by two researchers on an Excel© spreadsheet. Parameters collected from each study were author, country, type of study, period of study, size, age, gender, and factors studied. RESULTS: Out of 1,318 articles found, 24 were selected. The data contained 17,290 patients including 8,229 men, i.e. a male / female sex-ratio of 0.91. Factors studied were tobacco, alcohol, diet, infection, genetics and social factors. CONCLUSION: The results reported showed that several factors are associated with the occurrence of oral cavity cancers in Sub-Saharan Africa. There is a need to conduct further studies with more structured methodologies for more convincing results.

scholarly journals Human Papillomavirus Detection in Head and Neck Squamous Cell Carcinomas at a Tertiary Hospital in Sub-Saharan Africa

2019 ◽  
Vol 2019 ◽  
pp. 1-6
Author(s):  
Evans Aboagye ◽  
Francis Agyemang-Yeboah ◽  
Babatunde Moses Duduyemi ◽  
Christian Obirikorang
Keyword(s):  
Human Papillomavirus ◽  
Oral Cavity ◽  
Head And Neck ◽  
Squamous Cell ◽  
Tertiary Hospital ◽  
Sub Saharan Africa ◽  
Cross Sectional ◽  
Hpv 16 ◽  
Sub Saharan ◽  
Oral Cavity Cancers

Fewer studies have been done over the years to establish the association of human papillomavirus (HPV) with head and neck squamous cell carcinoma (HNSSC) within the subregions of sub-Saharan Africa, and thus this study was designed to investigate the presence of HPV in HNSCC at a tertiary hospital in Ghana, providing additional evidence on the need to explore similar studies in other subregions. A retrospective cross-sectional study was employed to investigate the presence of the DNA of HPV genotypes in HNSCC archived tissue. A total of 100 HNSCC cases were classified as suitable for HPV genotyping. HPV-DNA was detected in 18% of the HNSCC cases, with 17 being HPV-16 and 1 dual infection with HPV-16 and HPV-18. HPV was prevalent in 50% of oropharyngeal cancers, 27% of laryngeal cancers, and 23% of oral cavity cancers. HPV E6/E7 oncogenic DNA was found in 18% of the HNSCC cases, with HPV-16 being the predominant genotype present. The pattern of HPV association was similar to earlier reported studies, recording a higher prevalence in oropharyngeal cancers, followed by laryngeal cancers and oral cavity cancers.

scholarly journals Prevalence and Factors Associated with Malnutrition in Children Aged 6-59 Months in Jubek State, South Sudan.

2020 ◽  
Author(s):  
Martin Adelino Iyya ◽  
Ndeezi Grace ◽  
Nabukeera Barungi Nicolette ◽  
Hassan Chollong
Keyword(s):  
Diarrheal Disease ◽  
South Sudan ◽  
Public Health Problem ◽  
Sub Saharan Africa ◽  
Acute Malnutrition ◽  
Cross Sectional ◽  
Factors Associated ◽  
Hiv Test ◽  
Sub Saharan ◽  
Structured Questionnaire

Abstract Background: South Sudan is the world’s youngest nation which gained independence from Sudan on the 9th of July, 2011. Rates of acute malnutrition have been consistently higher in South Sudan than any other country in sub-Saharan Africa, more than twice the average reported for countries in Sub-Saharan Africa. This study sought to determine the prevalence and factors associated with malnutrition among children aged 6-59 months in Jubek State, South Sudan.Methods: This was a cross sectional analytical community based study to assess the prevalence and factors associated with malnutrition among children aged 6-59 months in Jubek State, South Sudan. Data was collected using a structured questionnaire from 396 children. Anthropometric measurements including weight, length/ height, mid upper arm circumference (MUAC) were taken and a blood sample by finger prick was removed for HIV test. The equipment which were used included: WHO recommended MUAC tape for 6months to 59 months old children, digital weighing scale (SECCA) and portable Stadiometers. Data were collected using a pretested semi- structured questionnaire. Results: The analysis of this study revealed that, 32.2%, 28.2% and 32.3% of children were stunted, wasted and underweight respectively. The main associated factors of stunting were age older than one year (p= 0.004), children from households who were renting their houses and children who defecate in open spaces with no latrine at their homes (p= 0.015). Underweight was associated with child’s age (p= 0.001), loss of appetite (p=<0.001), children who ate from own plate (p=0.001) and children who didn’t consume meat (p=0.007). Male genders (p=0.022), households with two or more children aged zero to five years (0.010) not consuming vitamin A rich vegetable (p=0.002), diarrheal disease within two weeks prior to interview (p=0.006) and those from households with water sources other than piped (<0.001) were also associated with wasting. Conclusion:The findings of this study indicate that malnutrition is still a serious public health problem among children below five years of age in Jubek state, South Sudan. Emergency intervention measures to address this critical levels of malnutrition are required.

scholarly journals Decomposing the rural–urban gap in factors associated with childhood immunisation in sub-Saharan Africa: evidence from surveys in 23 countries

2021 ◽  
Vol 6 (1) ◽  
pp. e003773
Author(s):  
Edward Kwabena Ameyaw ◽  
Yusuf Olushola Kareem ◽  
Bright Opoku Ahinkorah ◽  
Abdul-Aziz Seidu ◽  
Sanni Yaya
Keyword(s):  
Decomposition Analysis ◽  
Household Wealth ◽  
Sub Saharan Africa ◽  
Demographic And Health Surveys ◽  
Childhood Immunisation ◽  
Urban Settings ◽  
Factors Associated ◽  
Rural And Urban ◽  
Full Immunisation ◽  
Sub Saharan

BackgroundAbout 31 million children in sub-Saharan Africa (SSA) suffer from immunisation preventable diseases yearly and more than half a million children die because of lack of access to immunisation. Immunisation coverage has stagnated at 72% in SSA over the past 6 years. Due to evidence that full immunisation of children may be determined by place of residence, this study aimed at investigating the rural–urban differential in full childhood immunisation in SSA.MethodsThe data used for this study consisted of 26 241 children pooled from 23 Demographic and Health Surveys conducted between 2010 and 2018 in SSA. We performed a Poisson regression analysis with robust Standard Errors (SEs) to determine the factors associated with full immunisation status for rural and urban children. Likewise, a multivariate decomposition analysis for non-linear response model was used to examine the contribution of the covariates to the observed rural and urban differential in full childhood immunisation. All analyses were performed using Stata software V.15.0 and associations with a p<0.05 were considered statistically significant.ResultsMore than half of children in urban settings were fully immunised (52.8%) while 59.3% of rural residents were not fully immunised. In all, 76.5% of rural–urban variation in full immunisation was attributable to differences in child and maternal characteristics. Household wealth was an important component contributing to the rural–urban gap. Specifically, richest wealth status substantially accounted for immunisation disparity (35.7%). First and sixth birth orders contributed 7.3% and 14.9%, respectively, towards the disparity while 7.9% of the disparity was attributable to distance to health facility.ConclusionThis study has emphasised the rural–urban disparity in childhood immunisation, with children in the urban settings more likely to complete immunisation. Subregional, national and community-level interventions to obviate this disparity should target children in rural settings, those from poor households and women who have difficulties in accessing healthcare facilities due to distance.

scholarly journals Factors associated with maternal mortality in Sub-Saharan Africa: an ecological study

2009 ◽  
Vol 9 (1) ◽  
Author(s):  
Jose Luis Alvarez ◽  
Ruth Gil ◽  
Valentín Hernández ◽  
Angel Gil
Keyword(s):  
Maternal Mortality ◽  
Ecological Study ◽  
Sub Saharan Africa ◽  
Factors Associated ◽  
Sub Saharan

scholarly journals A brief review on features of falciparum malaria during pregnancy

2017 ◽  
Author(s):  
Alexandre Manirakiza ◽  
Eugène Serdouma ◽  
Richard Norbert Ngbalé ◽  
Sandrine Moussa ◽  
Samuel Gondjé ◽  
...  
Keyword(s):  
Falciparum Malaria ◽  
Public Health Problem ◽  
Malaria In Pregnancy ◽  
Sub Saharan Africa ◽  
Malaria During Pregnancy ◽  
Concurrent Infections ◽  
Tropical Areas ◽  
Sub Saharan ◽  
Protection Against Infection ◽  
In Pregnancy

Malaria in pregnancy is a serious public health problem in tropical areas. Frequently, the placenta is infected by accumulation of Plasmodium falciparum-infected erythrocytes in the intervillous space. Falciparum malaria acts during pregnancy by a range of mechanisms, and chronic or repeated infection and co-infections have insidious effects. The susceptibility of pregnant women to malaria is due to both immunological and humoral changes. Until a malaria vaccine becomes available, the deleterious effects of malaria in pregnancy can be avoided by protection against infection and prompt treatment with safe, effective antimalarial agents; however, concurrent infections such as with HIV and helminths during pregnancy are jeopardizing malaria control in sub-Saharan Africa.

scholarly journals Prise En Charge Des Péritonites Aiguës Dans Un Hôpital De District En Afrique Sub-saharienne : Cas Du Bénin

2017 ◽  
Vol 13 (36) ◽  
pp. 388
Author(s):  
Bio Tamou Sambo ◽  
Salako Alexandre Allodé ◽  
Didier Sewadé Wekpon ◽  
Djifid Morel Séto ◽  
Montcho Adrien Hodonou ◽  
...  
Keyword(s):  
Mortality Rate ◽  
District Hospital ◽  
Public Health Problem ◽  
Sub Saharan Africa ◽  
Prise En Charge ◽  
Prospective Data ◽  
Acute Peritonitis ◽  
Generalized Peritonitis ◽  
Sub Saharan ◽  
Surgery Department

Introduction: Peritonitis remains a public health problem in Africa. We aim to describe the epidemiological, etiological and therapeutic aspects of acute peritonitis in a district hospital in Sub Saharan Africa. Methods: This was a descriptive study with prospective data collection over a period of 15 months from May 1 st 2015 to July 31st 2016 in Bembereke district hospital. It has taken into account all the patients managed in the general surgery department for acute generalized peritonitis that has been confirmed at laparotomy. Results: Fifty-three patients, 38 men (71.7 %) and 15 women (28.3 %) had been registered. The average age of the patients was 19.8 ± 16.9 years. The main etiologies were: non-traumatic ileal perforation from typhoid infection 52.8%; perforated gastric or duodenal ulcer 17%; complicated appendicitis and abdominal traumas 11.3% each one. Twenty nine patients (54.7%) have been operated by a surgeon and the 24 remaining (45.3%) by a general practitioner with surgical skills. Twenty one patients (39.6%) had postoperative complications of which 11 cases of parietal suppurations (52.4%). The mortality rate was 11.3%. The mean hospital stay was 22.5 ± 4 days. Conclusion: In northern-Benin, peritonitis remains dominated by the complications of typhoid fever. The mortality rate remains high. Prevention requires good hygiene and awareness of early consultations.

scholarly journals Estimating the timing of multiple admixture pulses during local ancestry inference

2018 ◽  
Author(s):  
Paloma Medina ◽  
Bryan Thornlow ◽  
Rasmus Nielsen ◽  
Russell Corbett-Detig
Keyword(s):  
Biological Process ◽  
Genetic Material ◽  
Simulated Data ◽  
Sub Saharan Africa ◽  
African Populations ◽  
Fundamental Biological Process ◽  
Admixed Population ◽  
Sub Saharan ◽  
Local Ancestry Inference ◽  
Admixture Event

ABSTRACTAdmixture, the mixing of genetically distinct populations, is increasingly recognized as a fundamental biological process. One major goal of admixture analyses is to estimate the timing of admixture events. Whereas most methods today can only detect the most recent admixture event, here we present coalescent theory and associated software that can be used to estimate the timing of multiple admixture events in an admixed population. We extensively validate this approach and evaluate the conditions under which it can succesfully distinguish one from two-pulse admixture models. We apply our approach to real and simulated data of Drosophila melanogaster. We find evidence of a single very recent pulse of cosmopolitan ancestry contributing to African populations as well as evidence for more ancient admixture among genetically differentiated populations in sub-Saharan Africa. These results suggest our method can quantify complex admixture histories involving genetic material introduced by multiple discrete admixture pulses. The new method facilitates the exploration of admixture and its contribution to adaptation, ecological divergence, and speciation.

scholarly journals Prevalence of Anemia and Undernutrition of Adolescent Females in Selected Schools in Ghana

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Marina Aferiba Tandoh ◽  
Abigail Owusuaa Appiah ◽  
Anthony Kwaku Edusei
Keyword(s):  
Public Health Problem ◽  
Cross Sectional Study ◽  
Adolescent Females ◽  
Sub Saharan Africa ◽  
Health And Wellness ◽  
Cross Sectional ◽  
High Prevalence ◽  
Sub Saharan ◽  
Poor Nutrition ◽  
Prevalence Of Anemia

Anemia among adolescent females is a major worldwide public health problem which should be given appropriate attention. Half of all anemic cases are caused by iron deficiency. In addition to anemia, poor nutrition is also a challenge in sub-Saharan Africa. This study determined the prevalence of anemia and undernutrition among adolescent females in school. A cross-sectional study was conducted among 151 adolescent females in four basic schools in the Ahafo region of Ghana. The hemoglobin level and anthropometry measures of participants were taken to determine their anemic and nutritional status. The prevalence of anemia among adolescent females in school was 50.3%. Out of the 151 participants, 6.6%, 19.9%, and 23.8% were severely anemic, moderately anemic, or mildly anemic, respectively. Only 2% of the participants were underweight, but the rate of stunting was 26.5%. The notable high prevalence of anemia that was found among adolescent females was correlated with other health and wellness concerns. Anemia and under nutrition negatively affect academic performance, productivity, and general wellbeing of adolescents; therefore, effective measures should be put in place to correct and eradicate these nutritional problems.

scholarly journals The prevalence of scabies in Monrovia, Liberia: a population-based survey

2020 ◽  
Author(s):  
Shelui Collinson ◽  
Joseph Timothy ◽  
Samuel K Zayay ◽  
Karsor K Kollie ◽  
Eglantine Lebas ◽  
...  
Keyword(s):  
Public Health ◽  
Quality Of Life ◽  
Health Problem ◽  
Public Health Problem ◽  
Sub Saharan Africa ◽  
Quality Data ◽  
Local Health ◽  
Sub Saharan ◽  
The Impact

AbstractBackgroundScabies is known to be a public health problem in many settings but the majority of recent data is from rural settings in the Pacific. There is a need for high quality data from sub-Saharan Africa and peri-Urban settings to inform scale up of scabies control efforts. There have been anecdotal reports of scabies being a public health problem in Liberia but robust data are lacking.MethodsWe conducted a cross-sectional cluster-randomised prevalence survey for scabies in a peri-urban community in Monrovia, Liberia in February-March 2020. Participants underwent a standardised examination conducted by trained local health care workers. Health related quality of life (HRQoL) was assessed using age-appropriate dermatology life quality indices (DLQIs). Prevalence estimates were calculated accounting for clustering at community and household levels and associations with key demographic variables assessed through multivariable random-effects logistic regression.Results1,318 participants from 477 households were surveyed. The prevalence of scabies prevalence was 9.3% (95% CI: 6.5-13.2%), across 75 (19.7%) households; impetigo or infected scabies prevalence was 0.8% (95% CI: 0.4-1.9%). The majority (52%) of scabies cases were classified as severe. Scabies prevalence was lower in females and higher in the youngest age group; no associations were found with other collected demographic or socio-economic variables. DLQI scores indicated a very or extremely large effect on HRQoL in 29% of adults and 18% of children diagnosed with scabies.ConclusionsOur study indicates a substantial burden of scabies in this peri-Urban population in Liberia. This was associated with significant impact on quality of life, highlighting the need for action to control scabies in this population. Further work is needed to assess the impact of interventions in this context on both the prevalence of scabies and quality of life.Plain English summaryScabies is an infestation with a microscopic mite which affects many people living in low-resource tropical countries. It causes intense itching, which can lead to complications through bacterial infection and poor quality of life. To help develop global scabies control programmes, we need a better understanding of how common it is across different tropical settings. We conducted a survey to assess the burden of scabies and bacterial skin infection in a random sample of people living in a community in Monrovia, Liberia. Information about participants and their household were collected and their skin was examined; those with skin conditions were asked about its impact on quality of life.We examined 1,318 participants and found that almost 10% of people had scanies. Scabies was more common in young children, and was more common in male children than female children. We found that there was a large impact on quality of life due mostly to the itching that scabies causes and to people feeling embarrassed or sad because of their skin condition. This scabies survey is one of the first conducted across all age groups in recent years in sub-Saharan Africa and indicates a substantial burden and impact on quality of life. More work is needed to understand how common scabies is in different settings and the impact that different treatment strategies may have.

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