Experimental production of human "blue velvet" and "red devil" lesions

JAMA ◽  
1966 ◽  
Vol 197 (13) ◽  
pp. 1100-1102 ◽  
Author(s):  
H. E. Puro
2019 ◽  
pp. 3-8
Author(s):  
N.Yu. Bobrovskaya ◽  
M.F. Danilov

The criteria of the coordinate measurements quality at pilot-experimental production based on contemporary methods of quality management system and traditional methods of the measurements quality in Metrology are considered. As an additional criterion for quality of measurements, their duration is proposed. Analyzing the problem of assessing the quality of measurements, the authors pay particular attention to the role of technological heredity in the analysis of the sources of uncertainty of coordinate measurements, including not only the process of manufacturing the part, but all stages of the development of design and technological documentation. Along with such criteria as the degree of confidence in the results of measurements; the accuracy, convergence, reproducibility and speed of the results must take into account the correctness of technical specification, and such characteristics of the shape of the geometric elements to be controlled, such as flatness, roundness, cylindrical. It is noted that one of the main methods to reduce the uncertainty of coordinate measurements is to reduce the uncertainty in the initial data and measurement conditions, as well as to increase the stability of the tasks due to the reasonable choice of the basic geometric elements (measuring bases) of the part. A prerequisite for obtaining reliable quality indicators is a quantitative assessment of the conditions and organization of the measurement process. To plan and normalize the time of measurements, the authors propose to use analytical formulas, on the basis of which it is possible to perform quantitative analysis and optimization of quality indicators, including the speed of measurements.


2020 ◽  
Vol 45 (1) ◽  
pp. 15-30
Author(s):  
Yasuhiro Shimotsuura ◽  
Hiroyuki Maezawa ◽  
Yoshiaki Omura

As Bi-Digital O-Ring Test (originated and founded by Prof. Y. Omura in New York, 1997-2020; follow as BDORT)is a diagnosis method that is carried out on the basic theory of the physiological phenomenon called the decline of muscular power of fingers, the examiner, and patients (or mediator) are demanded to do BDORT by constant regular power. Namely BDORT is a diagnosis method that estimates the relative muscular decline of the patients, so there is such a view that the results of BDORT are reflected by consciousness of the examiner. The authors used the ORT tester by using air system to avoid the influence of electromagnetic wave and evaluated the decline of the muscle strength and open degree of the O-ring shaped by the patients. Patients of the Shimotsuura Clinic are subjected and checked by direct BDORT method. When the patients shapes the O-Ring, staff members stimulated the parts of the body by plastic stick and push foot switch. Decline of the muscle strength & open degree was evaluated. When the open degree was more than 20%, stimulated points were evaluated as abnormal. Opposite side arm of the O-Ring shaped arm was checked as control. The results of the direct BDORT method between ORT evaluation apparatus and the patient was consistent with the results of the indirect method of BDORT method between the doctor and the assistant. Even where the patients complain of ill, the muscle strength was declined and opened the O-Ring by using ORT evaluation apparatus. Especially in the parts of the strong response of Integrin α5β1 checked by the doctor, the muscle strength decreased and the open degree was much higher than other parts of the body. Patients could experience of BDORT by numeral objective evaluation of the decline of the muscle strength by using ORT evaluation apparatus.


2019 ◽  
pp. 146-156
Author(s):  
F. A. Nasonov ◽  
V. M. Aleksashin ◽  
D. A. Melnikov ◽  
S. V. Bukharov

The influence of the special modification of epoxy resins and polymer composites based on them on the basic technological properties of the composition is investigated. Modification is performed in order to reduce the opening damage. The most important technological properties of the initial epoxy composition and modified technological additives are studied and compared by standard methods (viscosimetry, thermoanalytical methods). A kinetic model of the curing process was created, the experimental production of samples from plastics filled with carbon long filler (impregnation under pressure, autoclave molding) and its non-destructive testing were carried out.


1968 ◽  
Vol 7 (3) ◽  
pp. 535 ◽  
Author(s):  
William J. Siemens-Wapniarski ◽  
M. Parker Givens

The experiment herein described was undertaken at the Central Research Institute, Kasauli, India. It commenced on September 6, 1913, and terminated, owing to my recall to military duty for active service, on December 24, 1914. Having been on service for the past 18 months I have not hitherto had an opportunity to report it. Object of the Experiment . Its object was to determine the cause of congenital goitre and the conditions under which it developed in large animals, and to confirm and amplify the results I had obtained by previous experimentation on white rats.


1988 ◽  
Vol 15 (4) ◽  
pp. 313-318
Author(s):  
Anthony Stevens

During the last twenty years, the most enthusiastic advocates of the use of animal models in the study of human psychiatric dysfunction have been Harlow and Suomi. In an influential paper, Induced Depression in Monkeys (1974), they argued that more extensive use of non-human primates “would have great potential utility since many manipulations and measurements presently prohibited in human study by ethical and practical considerations could be readily performed on non-human primate subjects in well-controlled experimental environments.” Harlow & Suomi concluded this paper with the following statement: “The results obtained to date on induced depression in monkeys show that proper and profound depressions can be produced relatively easily by a variety of techniques. These induced depressions either bear a close resemblance to human depression or have such similarity as to suggest that closely correlated human and animal depressive patterns may be achieved with refined techniques. The results to date also provide adequate data for the conduct of meaningful researches on the effects of pharmacological agents which either enhance, inhibit or preclude the experimental production of depression. Further, the existence of firm and fast monkey depression syndromes offers vast opportunities for testing a wide range of therapeutic techniques, either behavioural or biochemical.”


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