Needle-Free Dermal Filler Injectors Prompt Safety Warning

JAMA ◽  
2021 ◽  
Vol 326 (19) ◽  
pp. 1899
Author(s):  
Rebecca Voelker
Keyword(s):  
Polymers ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 948
Author(s):  
Nicola Zerbinati ◽  
Sabrina Sommatis ◽  
Cristina Maccario ◽  
Maria Chiara Capillo ◽  
Giulia Grimaldi ◽  
...  

(1) Background: Injectable hyaluronic acid (HA) dermal fillers are used to restore volume, hydration and skin tone in aesthetic medicine. HA fillers differ from each other due to their cross-linking technologies, with the aim to increase mechanical and biological activities. One of the most recent and promising cross-linkers is polyethylene glycol diglycidyl ether (PEGDE), used by the company Matex Lab S.p.A., (Brindisi, Italy) to create the HA dermal filler PEGDE family. Over the last few years, several studies have been performed to investigate the biocompatibility and biodegradability of these formulations, but little information is available regarding their matrix structure, rheological and physicochemical properties related to their cross-linking technologies, the HA content or the degree of cross-linking. (2) Methods: Seven different injectable HA hydrogels were subjected to optical microscopic examination, cohesivity evaluation and rheological characterization in order to investigate their behavior. (3) Results: The analyzed cross-linked dermal fillers showed a fibrous “spiderweb-like” matrix structure, with each medical device presenting different and peculiar rheological features. Except for HA non cross-linked hydrogel 18 mg/mL, all showed an elastic and cohesive profile. (4) Conclusions: The comparative analysis with other literature works makes a preliminary characterization of these injectable medical devices possible.


2021 ◽  
pp. 074880682199140
Author(s):  
Manish J. Patel ◽  
Mit M. Patel ◽  
Brittany T. Abud ◽  
Robert T. Cristel

YouTube proves to be a source of health information for patients. This is the first study to analyze the source reliability and educational value of YouTube videos on facial filler treatments. On August 12, 2020, YouTube.com was queried using the keywords “facial filler” or “dermal filler” or “fillers.” A total of 100 were initially reviewed in which 74 videos met the inclusion criteria and were included in the final analysis. Video characteristics were recorded, and each video was graded for source reliability and educational value by using the Journal of the American Medical Association (JAMA) benchmark criteria and the Global Quality Score (GQS), respectively. Furthermore, each video was assessed to determine whether there was discussion of 5 different topics that were deemed to be useful to patients prior to undergoing a facial filler treatment. A total of 74 videos met the inclusion criteria and had an average length of 436 seconds (7 minutes and 16 seconds), 146 805 views, 1906 likes, 73 dislikes, and 241 comments. Forty-five videos (61%) were posted with an intention to educate patients, whereas 29 videos (39%) were posted with an intention to describe a patient’s experience with facial filler treatment. Patient education videos were found to have a significantly higher educational value ( PGQS < .001). Patient experience videos showed no difference in reliability score ( PJAMA > .05) to patient education videos, but patient experience videos were found to have lower educational value compared with patient education videos ( PGQS < .001). In addition, both categories are not providing sufficient information for informed decision-making prior to treatment deemed by the 5 selected categories we found most informative. As patients will continue to seek educational material online, clinicians should use this information to help primarily educate patients with standardized and accurate information about their treatment.


Electronics ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 302
Author(s):  
Chunde Liu ◽  
Xianli Su ◽  
Chuanwen Li

There is a growing interest in safety warning of underground mining due to the huge threat being faced by those working in underground mining. Data acquisition of sensors based on Internet of Things (IoT) is currently the main method, but the data anomaly detection and analysis of multi-sensors is a challenging task: firstly, the data that are collected by different sensors of underground mining are heterogeneous; secondly, real-time is required for the data anomaly detection of safety warning. Currently, there are many anomaly detection methods, such as traditional clustering methods K-means and C-means. Meanwhile, Artificial Intelligence (AI) is widely used in data analysis and prediction. However, K-means and C-means cannot directly process heterogeneous data, and AI algorithms require equipment with high computing and storage capabilities. IoT equipment of underground mining cannot perform complex calculation due to the limitation of energy consumption. Therefore, many existing methods cannot be directly used for IoT applications in underground mining. In this paper, a multi-sensors data anomaly detection method based on edge computing is proposed. Firstly, an edge computing model is designed, and according to the computing capabilities of different types of devices, anomaly detection tasks are migrated to different edge devices, which solve the problem of insufficient computing capabilities of the devices. Secondly, according to the requirements of different anomaly detection tasks, edge anomaly detection algorithms for sensor nodes and sink nodes are designed respectively. Lastly, an experimental platform is built for performance comparison analysis, and the experimental results show that the proposed algorithm has better performance in anomaly detection accuracy, delay, and energy consumption.


Sensors ◽  
2021 ◽  
Vol 21 (4) ◽  
pp. 1146 ◽  
Author(s):  
Yincheng Li ◽  
Wenbin Zhang ◽  
Peng Li ◽  
Youhuan Ning ◽  
Chunguang Suo

At present, the method of using unmanned aerial vehicles (UAVs) with traditional navigation equipment for inspection of overhead transmission lines has the limitations of expensive sensors, difficult data processing, and vulnerable to weather and environmental factors, which cannot ensure the safety of UAV and power systems. Therefore, this paper establishes a mathematical model of spatial distribution of transmission lines to study the field strength distribution information around transmission lines. Based on this, research the navigation and positioning algorithm. The data collected by the positioning system are input into the mathematical model to complete the identification, positioning, and safety distance diagnosis of the field source. The detected data and processing results can provide reference for UAV obstacle avoidance navigation and safety warning. The experimental results show that the positioning effect of the positioning navigation algorithm is obvious, and the positioning error is within the range of use error and has good usability and application value.


2013 ◽  
Vol 131 (4) ◽  
pp. 597e-603e ◽  
Author(s):  
Paolo Persichetti ◽  
Dario Palazzolo ◽  
Stefania Tenna ◽  
Igor Poccia ◽  
Franca Abbruzzese ◽  
...  

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