Cytomegalovirus infection among employees of a children's hospital. No evidence for increased risk associated with patient care

JAMA ◽  
1990 ◽  
Vol 263 (6) ◽  
pp. 840-844 ◽  
Author(s):  
K. B. Balcarek
Author(s):  
Brian T. Fisher ◽  
Anna Sharova ◽  
Craig L. K. Boge ◽  
Sigrid Gouma ◽  
Audrey Kamrin ◽  
...  

Abstract Objectives: Describe cumulative seroprevalence of SARS-CoV-2 antibodies during the COVID-19 pandemic among employees of a large pediatric healthcare system. Design, Setting, and Participants: Prospective observational cohort study open to adult employees at Children’s Hospital of Philadelphia, conducted April 20 – December 17, 2020. Methods: Employees were recruited starting with high-risk exposure groups, utilizing emails, flyers, and announcements at virtual town halls. At baseline, 1-month, 2-month, and 6-month timepoints, participants reported occupational and community exposures and gave a blood sample for SARS-CoV-2 antibody measurement by enzyme-linked immunosorbent assays (ELISAs). A post hoc Cox proportional hazards regression model was performed to identify factors associated with increased risk for seropositivity. Results: 1740 employees were enrolled. At 6-months, cumulative seroprevalence was 5.3%, below estimated community point seroprevalence; seroprevalence was 5.8% and 3.4% among employees with and without direct patient care, respectively. Most participants seropositive at baseline remained positive at follow-up assessments. In post hoc analysis, direct patient care (HR: 1.95, 95% CI: 1.03 to 3.68), Black race (HR: 2.70, 95% CI: 1.24 to 5.87), and exposure to a confirmed case in a non-healthcare setting (HR: 4.32, 95% CI: 2.71 to 6.88) were associated with statistically significant increased risk for seropositivity. Conclusions: Employee SARS-CoV-2 seroprevalence rates remained below the surrounding community’s point prevalence rates. Provision of direct patient care, Black race, and exposure to a confirmed case in non-healthcare setting conferred increased risk. These data can inform occupational protection measures to maximize protection of employees within the workplace during future COVID waves or other epidemics.


PEDIATRICS ◽  
1967 ◽  
Vol 40 (3) ◽  
pp. 471-472
Author(s):  
T. BERRY BRAZELTON

In the past 2 years a new national organization, called the American Association for Child Care in Hospitals, has evolved. This organization was initiated by the six "play ladies" who are in charge of the children's hospital programs in Baltimore, Boston, Cleveland, Montreal, Philadelphia, and Pittsburgh. Two years ago, the Children's Hospital Medical Center (CHMC) in Boston was host to 50 participants from these institutions to found the organization. This initial meeting was abetted by the CHMC's concern for total patient care and was made possible by the backing of the administration and the pediatric and psychiatric departments.


F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 1699
Author(s):  
Michael Walekhwa ◽  
Margaret Muturi ◽  
Eucharia Kenya ◽  
Beatrice Kabera

Background: The spread of antimicrobial resistance threatens effective control and treatment of pneumococcal disease worldwide. In Kenya, an estimated one in every five children dies from pneumococcal disease every year. Of these, ≥50% are attributable to antibiotic resistance. Consequently, the WHO has recommended that continuous regional surveillance be done to detect early resistance to available antibiotics and make necessary changes. We therefore investigated antimicrobial susceptibility patterns of Streptococcus pneumoniae among PCV-10 vaccinated and unvaccinated children ≤5 years old at Gertrude's Children’s Hospital. Methods: A 0.5 McFarland standard of freshly subcultured organisms were inoculated on Mueller–Hinton plates with 5% sheep blood agar. A standard disk dispenser was used to dispense various antibiotic disks on the Mueller–Hinton agar plate. Incubation was done overnight (20-24 hours) at 37oC in 5% CO2 and clearance zones read using a Vanier caliber. Antimicrobials tested included vancomycin (30µg, ≥17mm); erythromycin (15µg, ≥21mm); clindamycin (2µg, ≥19mm); oxacillin (1µg, ≥19mm) and ceftriaxone (1µg, ≥30mm). Results: Thirty nine (92.86%) Streptococcus pneumoniae isolates were susceptible to erythromycin; 39 (92.86%) were susceptible to vancomycin; eight (19.86%) Streptococcus pneumoniae isolates were susceptible to oxacillin, while 34 (80.95%) were non-susceptible; 40 (95.24%) isolates were susceptible to clindamycin; and 24 (57.86%) isolates were susceptible to ceftriaxone, while 18 (42.86%) were non-susceptible. Children who attended daycare centers exhibited a four-fold significant risk of being resistant to ceftriaxone. All antibiotics studied were effective against Streptococcus pneumoniae except oxacillin and ceftriaxone, which exhibited high levels of non-susceptibility. Attendance of daycare centers, consumption of antibiotics two weeks prior to collection of sample and subject age were shown to be associated with an increased risk of Streptococcus pneumoniae being resistant to penicillins and ceftriaxone. Conclusions: The law guiding use of antibiotics in Kenya should be meritoriously enforced to curb abuse of the available antibiotics.


PEDIATRICS ◽  
1961 ◽  
Vol 28 (5) ◽  
pp. 695-696
Author(s):  
R. J. MCKAY

In this issue of Pediatrics the article entitled "A New Design for Patient Care and Pediatric Education in a Children's Hospital: An Interim Report," by Green and Segar, represents a challenging approach to problems that are of increasing concern to pediatric educators and pediatric services of medical centers throughout the United States. It should be emphasized that the authors' plan is a proposed solution to the problems involved, and that the question as to whether it will constitute an answer will have to await analysis not only of their results but of the results of other approaches to the same problems.


2009 ◽  
Vol 19 (1) ◽  
pp. 113-122 ◽  
Author(s):  
Mark Lilly

This article describes a comprehensive outline of suggested steps for founding a hospital-based Yoga therapy program. Bringing Yoga or other integrative modalities to inpatient settings is a very involved undertaking, both from an organizational and a therapeutic perspective. This article offers strategies for approaching hospitals; overcoming administrative, structural, legal, and cultural obstacles to developing a hospital-based program; integrating Yoga into patient care; and working with patients' families. To illustrate the general challenges, principles, and processes of forming a hospital-based Yoga therapy program, this article describes the author's experience of creating a Yoga therapy-based program for the Pediatric Development and Rehabilitation unit at Emanuel Children's Hospital in Portland, OR.


2021 ◽  
Author(s):  
David D. Schwartz ◽  
Mili Vakharia ◽  
Serife Uysal ◽  
Kristen R. Hendrix ◽  
Kelly Fegan-Bohm ◽  
...  

Texas Children’s Hospital, located in Houston, TX, is the largest pediatric hospital in the United States, with 973 inpatient beds and extensive outpatient clinics and services. It is the primary pediatric teaching hospital of Baylor College of Medicine. The Texas Children’s Endocrine and Diabetes Care Center is one of the largest pediatric endocrinology and diabetes centers in the country, with three inpatient facilities and seven ambulatory clinics. The service is staffed by a multidisciplinary team that includes endocrinologists, endocrine fellows, advanced practice providers, certified diabetes care and education specialists (CDCES), dietitians, social workers, and consulting psychologists. Almost 500 youth with newly diagnosed type 1 diabetes are admitted to the hospital each year, with a total pediatric diabetes population of >3,400 patients.


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