scholarly journals Ocular Antihypertensive Medication Use After iStent Implantation Concurrent With Cataract Surgery vs Cataract Surgery Alone in a Large US Health Care Claims Database

2019 ◽  
Vol 137 (1) ◽  
pp. 21 ◽  
Author(s):  
Sophia Y. Wang ◽  
Kuldev Singh ◽  
Joshua D. Stein ◽  
Robert T. Chang
2018 ◽  
Vol 136 (5) ◽  
pp. 548 ◽  
Author(s):  
Lucia Sobrin ◽  
Lynn K. Stanwyck ◽  
Wei Pan ◽  
Rebecca A. Hubbard ◽  
John H. Kempen ◽  
...  

SLEEP ◽  
2019 ◽  
Vol 42 (7) ◽  
Author(s):  
Darren Scheer ◽  
Skai W Schwartz ◽  
Maria Parr ◽  
Janice Zgibor ◽  
Aurora Sanchez-Anguiano ◽  
...  

AbstractStudy ObjectivesTo determine the prevalence and incidence of narcolepsy using a large US health care claims database.MethodsThe Truven Health MarketScan Commercial Dissertation Database (THMCDD) was used to estimate prevalence and incidence of narcolepsy, with and without cataplexy, by age groups, gender, and region among patients under age 66 years with continuous enrollment for years 2008–2010. THMCDD contains health claims information for more than 18 million people. Prevalence was expressed as cases/100 000 persons. Average annual incidence (using varying criteria for latency between the diagnostic tests, polysomnograph coupled with multiple sleep latency test [MSLT], and the diagnosis) was expressed as new cases/100 000 persons/year.ResultsThere were 8 444 517 continuously enrolled patients and 6703 diagnosed with narcolepsy (prevalence overall: 79.4/100 000; without cataplexy: 65.4/100 000; with cataplexy: 14.0/100 000). On the basis of the three definitions of incidence, overall average annual incidence was 7.67, 7.13, and 4.87/100 000 persons/year. Incidence for narcolepsy without cataplexy was generally several times higher than narcolepsy with cataplexy. Prevalence and incidence were approximately 50% greater for females compared to males across most age groups. Prevalence was highest among the 21–30 years age group, with incidence highest among enrollees in their early 20s and late teens. Regionally, the North Central United States had the highest prevalence and incidence, whereas the West was the lowest.ConclusionWe found greater prevalence and incidence of narcolepsy (including without cataplexy) than most previous studies. The increased proportions in females, enrollees in their early 20s, and US regional differences require further study. Increased awareness and early identification is critical in the management of this burdensome condition.


Hypertension ◽  
2017 ◽  
Vol 70 (suppl_1) ◽  
Author(s):  
Jing Fang ◽  
Carma Ayala ◽  
Fleetwood Loustalot

Background: Hypertension is a major risk factor for heart disease and stroke; yet only half of those with hypertension have it under control. One of the Healthy People 2020 goals is to increase the proportion of adults with hypertension who are taking antihypertensive medications to lower their blood pressure from a baseline of 63.2% to a target of 69.5% by 2020. The objective of this study was to examine progress towards meeting this national objective and to assess disparities mid-decade. Methods: Adult participants (≥18 years) with self-reported hypertension from the National Health Interview Survey in 2014 and 2015 were included in this study. Current antihypertensive medication use was assessed and age-standardized for analysis. Multivariable logistic regression models were used to determine the odds ratio of antihypertensive medication use, adjusting for age, sex, race/ethnicity, education and health care access status. Results: Among the 21,050 (26.7%) adults with self-reported hypertension, 69.2% reported current antihypertensive medication use and disparities were noted among subgroups. Adults with estimates of antihypertensive medication use that fell below the Healthy People 2020 goal (69.5%) included women, non-Hispanic whites, Hispanics, and those with access health care barriers (Table). Conclusion: To control hypertension, most patients require antihypertensive medications to achieve control. Understanding disparities in antihypertensive medication utilization is needed for all population to achieve Healthy People 2020 targets by the end of the decade.


2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Nancy D. Lin ◽  
Heather Norman ◽  
Arie Regev ◽  
David G. Perahia ◽  
Hu Li ◽  
...  

Cephalalgia ◽  
2016 ◽  
Vol 36 (9) ◽  
pp. 862-874 ◽  
Author(s):  
Zsolt Hepp ◽  
Noah L Rosen ◽  
Patrick G Gillard ◽  
Sepideh F Varon ◽  
Nitya Mathew ◽  
...  

Background Migraine, especially chronic migraine (CM), causes substantial disability; however, health care utilization has not been well characterized among patients receiving different migraine prophylactic treatments. Methods Using a large, US-based, health care claims database, headache-related health care utilization was evaluated among adults with CM treated with onabotulinumtoxinA or oral migraine prophylactic medications (OMPMs). Headache-related health care utilization was assessed at six, nine, and 12 months pre- and post-treatment. The primary endpoint was the difference between pre- and post-index headache-related health care utilization. A logistic regression model was created to test the difference between onabotulinumtoxinA and OMPM-treated groups for headache-related emergency department (ED) visits and hospitalizations. Results Baseline characteristics were comparable between groups. The proportion of patients with ED visits or hospitalizations for a headache-related event decreased after starting onabotulinumtoxinA, but increased after starting an OMPM, for all three cohorts. Regression analyses showed that the odds of having a headache-related ED visit were 21%, 20%, and 19% lower and hospitalization were 47%, 48%, and 56% lower for the onabotulinumtoxinA group compared to the OMPM group for the six-month, nine-month, and 12-month post-index periods, respectively. Conclusions When compared with similar patients who initiated treatment with OMPM, onabotulinumtoxinA was associated with a significantly lower likelihood of headache-related ED visits and hospitalizations.


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