Morphological Evolution and Magnetic Property of Rare-Earth-Doped Hematite Nanoparticles: Promising Contrast Agents for T1-Weighted Magnetic Resonance Imaging

2017 ◽  
Vol 27 (27) ◽  
pp. 1606821 ◽  
Author(s):  
Hao Wan ◽  
Pengfei Rong ◽  
Xiaohe Liu ◽  
Litong Yang ◽  
Yong Jiang ◽  
...  
2020 ◽  
Vol 8 (36) ◽  
pp. 8356-8367
Author(s):  
Gohar Ijaz Dar ◽  
M. Zubair Iqbal ◽  
Ozioma Udochukwu Akakuru ◽  
Chenyang Yao ◽  
Gul Awiaz ◽  
...  

The integration of advanced diagnostic contrast agents with versatile therapeutic nanoparticles presents an effective method for cancer treatment.


2014 ◽  
Vol 2 (35) ◽  
pp. 5891-5897 ◽  
Author(s):  
Ningqi Luo ◽  
Chuan Yang ◽  
Xiumei Tian ◽  
Jun Xiao ◽  
Jun Liu ◽  
...  

A general strategy, combining laser ablation in liquid with a standard solid state reaction technique, is developed to prepare dualmodal contrast agents for fluorescence and magnetic resonance imaging applications.


2016 ◽  
Vol 4 (24) ◽  
pp. 4313-4321 ◽  
Author(s):  
X. W. Li ◽  
W. R. Zhao ◽  
Y. J. Liu ◽  
X. H. Liu ◽  
P. Shi ◽  
...  

Manganese silicate nanoparticles were facilely synthesized and showed high potential as T1-MRI contrast agents for cancer diagnosis.


2020 ◽  
Vol 6 (12) ◽  
pp. 6971-6980
Author(s):  
Anne E. D’Achille ◽  
Roberto Gonzalez-Rodriguez ◽  
Elizabeth Campbell ◽  
Bong Han Lee ◽  
Jeffery L. Coffer ◽  
...  

2018 ◽  
Vol 46 (3) ◽  
pp. 289-295
Author(s):  
M. Yu. Yukina ◽  
N. F. Nuralieva ◽  
E. A. Troshina ◽  
A. V. Vorontsov ◽  
V. P. Vladimirova ◽  
...  

The topical diagnosis of insulinoma continues to be an actual problem of modern medicine due to low detection rate of the tumor (about 75%) and inconsistent data on its localization when using various methods of visualization (more than in 50% of cases), as well as the lack of a single diagnostic algorithm. In the clinical practice, many different imaging assessments are conducted, including those with the administration of contrast agents and associated with radiation load, as well as invasive studies, associated with risk of various complications, high costs and duration of the examination. Thus, the search for highly sensitive and safe methods of topical diagnosis of the insulin-producing pancreatic tumor seems relevant. In the presented clinical case, the diagnosis of insulinoma is verified by diffusion-weighted magnetic resonance imaging (DW-MRI). It is an accurate and non-invasive method that does not involve exposure to ionizing radiation and does not require any administration of contrast agents. This technology, based on microstructural pathological changes, allows to identify small tumors and to make a differential diagnosis of benign and malignant neoplasms. However, at present the experience of DW-MRI use for the diagnosis of an insulin-producing neuroendocrine tumor is limited. Evaluation of its effectiveness in a large patient cohort would be necessary to assess the prospects for its introduction into clinical practice.


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