scholarly journals Sarcopenia discriminates poor prognosis in elderly patients following emergency surgery for perforation panperitonitis

2019 ◽  
Vol 3 (6) ◽  
pp. 630-637
Author(s):  
Nobuhide Kubo ◽  
Hirohumi Kawanaka ◽  
Shoji Hiroshige ◽  
Hirotada Tajiri ◽  
Akinori Egashira ◽  
...  
Keyword(s):  
Elderly Patients ◽  
Emergency Surgery ◽  
Poor Prognosis

The Obesity Paradox in Elderly Patients Undergoing Emergency Surgery: A Nationwide Analysis

2021 ◽  
Vol 265 ◽  
pp. 195-203
Author(s):  
Mohamad El Moheb ◽  
Zhenyi Jia ◽  
Huanlong Qin ◽  
Majed W. El Hechi ◽  
Ask T. Nordestgaard ◽  
...  
Keyword(s):  
Elderly Patients ◽  
Emergency Surgery ◽  
Obesity Paradox

scholarly journals Risk analysis of 2-year mortality in elderly male military veterans with non-thyroidal illness syndrome​

2020 ◽  
Author(s):  
Xinyu Miao ◽  
Hongzhou Liu ◽  
Xiaomin Fu ◽  
Huiping Ma ◽  
Xuefeng Chen ◽  
...  
Keyword(s):  
Survival Rate ◽  
Elderly Patients ◽  
Poor Prognosis ◽  
Characteristic Curve ◽  
Fasting Blood Glucose ◽  
Mortality Prediction ◽  
Elderly Male ◽  
Biochemical Indicators ◽  
All Cause Mortality ◽  
Group Serum

Abstract Background: Elderly patients with non-thyroidal illness syndrome (NTIS) have relatively severe symptoms and a poor prognosis. However, there are few studies on the correlation between NTIS and mortality among hospitalised elderly patients. This study aimed to investigate the characterization of NTIS inpatients with biochemical indicators and mortality prediction.Methods: In the present study, 931 male veteran inpatients ≥ 60 years of age who visited our hospital from January 2012 to December 2013 were selected and divided into the NTIS group (n = 193) and normal thyroid function (non-NTIS) group（n = 738). Following propensity score matching to match the two groups according to age and body mass index, the NTIS group and non-NTIS group consisted of 192 and 660 patients, respectively. Data on biochemical indicators and mortality were collected. Results: Patients had more primary care and more respiratory disease and chronic kidney disease in the NTIS than in the non-NTIS group. Serum total protein (TP), albumin (Alb), prealbumin (PA), haemoglobin (Hb), uric acid (UA), triglyceride (TG), and high-density lipoprotein cholesterol (HDLC) levels were significantly lower, and fasting blood glucose (FBG) and urea nitrogen (UN) levels were higher, in the NTIS than in the non-NTIS group. Triiodothyronine, TP, Alb, and PA levels correlated positively with the Hb level and negatively with FBG, UN, and creatinine (Cr) levels. The free T3 level correlated positively with TP, Alb, PA, Hb, and UA levels and negatively with FBG, UN, and Cr levels. A lower free T3 level was associated with increased all-cause mortality after adjusting for covariates. Patients in the NTIS group had a lower survival rate at 6-month (78.65% vs. 97.73%), 1-year (68.23% vs. 96.97%) and 2-year (64.58% vs. 86.52%). Receiver operating characteristic curve (ROC) analysis showed that a cut-off free T3 level of 3.45 pmol/L yielded the highest sensitivity and specificity for predicting all-cause mortality at 2 years.Conclusion: Among elderly male inpatients, the survival rate was lower in the NTIS group. Serum protein levels and renal function decreased and the FBG level increased with decreasing triiodothyronine and free T3 levels. A decreased free T3 level in hospitalized elderly male patients was a predictor of poor prognosis.

Operative and prognostic parameters associated with elective versus emergency surgery in a retrospective cohort of elderly patients

2018 ◽  
Vol 31 (3) ◽  
pp. 403-410 ◽  
Author(s):  
Celaleddin Soyalp ◽  
Nureddin Yuzkat ◽  
Mehmet Kilic ◽  
Mehmet Edip Akyol ◽  
Canser Yilmaz Demir ◽  
...  
Keyword(s):  
Elderly Patients ◽  
Emergency Surgery ◽  
Retrospective Cohort ◽  
Prognostic Parameters

Soluble levels of sCD40L and s4‐1BB are associated with a poor prognosis in elderly patients with colorectal cancer

2019 ◽  
Author(s):  
Petrus M. A. Lima ◽  
Leuridan C. Torres ◽  
Mário R. Martins ◽  
Marina C. Matta ◽  
Jurema T. O. Lima ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Elderly Patients ◽  
Poor Prognosis

scholarly journals Survival Analysis in Elderly Patients with Glioblastomas: The Influence of Clinical Status, Tumor and Surgical Features

2018 ◽  
Vol 37 (04) ◽  
pp. 297-303
Author(s):  
Ulysses Sousa ◽  
Matheus Oliveira ◽  
Lindolfo Heringer ◽  
Ricardo Botelho ◽  
José Rotta
Keyword(s):  
Survival Analysis ◽  
Elderly Patients ◽  
Poor Prognosis ◽  
Perioperative Complications ◽  
Clinical Status ◽  
Tumor Location ◽  
Malignant Neoplasms ◽  
Women Patients ◽  
The Impact

Introduction Glioblastomas are malignant neoplasms, notorious for their poor prognosis. We have conducted a survival analysis in a sample of elderly patients with glioblastomas. Methods The sample of the present study consisted of elderly patients consecutively admitted from January 2014 to January 2016 (24 months) at the Hospital do Servidor Público Estadual de São Paulo. We have evaluated the impact of age, Karnofsky scale (KS) score, tumor location, and occurrence of perioperative complications. Results A total of 42 patients were analyzed. Of these, 23 (54.7%) were men, and 19 (45.3%) were women. Patients > 60 years old, with low KS score, deep-seated tumors, and those with perioperative complications had worst outcomes. Discussion and conclusion Surgery, perioperative chemotherapy and radiotherapy add survival time and quality of life to these patients. In patients with low KS score, isolated radiotherapy and/or chemotherapy might be adequate. Decreasing perioperative complications is essential to adequately deliver adjuvant therapy in elderly patients.

Survival of Elderly Patients on Peritoneal Dialysis: Retrospective Study of 292 Patients, from 1982 to 1999

2002 ◽  
Vol 22 (1) ◽  
pp. 73-81 ◽  
Author(s):  
François Vrtovsnik ◽  
Raphaël Porcher ◽  
Catherine Michel ◽  
Gilles Hufnagel ◽  
Guillaume Queffeulou ◽  
...  
Keyword(s):  
Peritoneal Dialysis ◽  
Retrospective Study ◽  
Mortality Rate ◽  
Sex Ratio ◽  
Elderly Patients ◽  
Poor Prognosis ◽  
Patient Survival ◽  
University Hospital ◽  
Initiation Of Dialysis ◽  
Comorbidity Index

Background Dialysis is becoming increasingly frequent in patients over 75 years of age. Age is a superimposed comorbid factor commonly associated with poor prognosis in these patients. Objective To analyze the survival of 292 patients aged over 75 years on initiation of peritoneal dialysis (PD) from September 1982 to September 1999. Design Retrospective study. Setting Nephrology department in a University Hospital. Results Mean age was 81.5 years (range 75 – 92 years); 178 patients were over 80 years and 60 patients were over 85 years. Sex ratio was 136F/156M. Ninety-day mortality rate was 12%. Excluding the first 3 months, median patient survival was 21.6 months; 226 patients died on PD and 24 were shifted to hemodialysis. Survival was inversely correlated with the Charlson combined comorbidity index (CCI), but independent of predialysis hemoglobin and serum albumin levels. Over three selected periods, 1982 – 1989, 1989 – 1995, and 1995 – 1999, an increase was found in mean age (79.7 ± 3.3, 82.6 ± 3.9, and 81.8 ± 4.4 years; p < 0.001), CCI (7.6 ± 1.59, 8.0 ± 1.52, and 8.5 ± 1.63; p = 0.01), and predialysis creatinine clearance (6.2 ± 2.3, 6.4 ± 2.4, and 9.8 ± 3.8 mL/minute; p < 0.001). Median survival was similar in the various selected periods (21.0, 21.5, and 25.4 months). The incidence of peritonitis decreased from 0.63 to 0.21 episodes per patient year. Conclusion From 1982 to 1999, mean age and comorbidity increased on initiation of dialysis in elderly patients, with no increase in mortality. Survival in elderly patients on PD was related to the age–comorbidity index.

PLASMA LEVELS OF SCD40L AND S4-1BB ARE ASSOCIATED WITH A POOR PROGNOSIS IN COLORECTAL CANCER IN ELDERLY PATIENTS

2019 ◽  
Vol 10 (6) ◽  
pp. S110
Author(s):  
J.T. Sales ◽  
L.C. Torres ◽  
M.G. Mello ◽  
E.A. Fonte ◽  
G.L. De Almeida ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Elderly Patients ◽  
Plasma Levels ◽  
Poor Prognosis

scholarly journals The Emergency Surgery Frailty Index (EmSFI): development and internal validation of a novel simple bedside risk score for elderly patients undergoing emergency surgery

2020 ◽  
Author(s):  
Gianluca Costa ◽  
◽  
Laura Bersigotti ◽  
Giulia Massa ◽  
Luca Lepre ◽  
...  
Keyword(s):  
Elderly Patients ◽  
Surgical Procedures ◽  
Emergency Surgery ◽  
Characteristic Curve ◽  
Frailty Index ◽  
Univariate Analysis ◽  
The Elderly ◽  
Predictive Score ◽  
Internal Validation ◽  
Discrimination Ability

Abstract Background Frailty assessment has acquired an increasing importance in recent years and it has been demonstrated that this vulnerable profile predisposes elderly patients to a worse outcome after surgery. Therefore, it becomes paramount to perform an accurate stratification of surgical risk in elderly undergoing emergency surgery. Study design 1024 patients older than 65 years who required urgent surgical procedures were prospectively recruited from 38 Italian centers participating to the multicentric FRAILESEL (Frailty and Emergency Surgery in the Elderly) study, between December 2016 and May 2017. A univariate analysis was carried out, with the purpose of developing a frailty index in emergency surgery called “EmSFI”. Receiver operating characteristic curve analysis was then performed to test the accuracy of our predictive score. Results 784 elderly patients were consecutively enrolled, constituting the development set and results were validated considering further 240 consecutive patients undergoing colorectal surgical procedures. A logistic regression analysis was performed identifying different EmSFI risk classes. The model exhibited good accuracy as regard to mortality for both the development set (AUC = 0.731 [95% CI 0.654–0.772]; HL test χ2 = 6.780; p = 0.238) and the validation set (AUC = 0.762 [95% CI 0.682–0.842]; HL test χ2 = 7.238; p = 0.299). As concern morbidity, our model showed a moderate accuracy in the development group, whereas a poor discrimination ability was observed in the validation cohort. Conclusions The validated EmSFI represents a reliable and time-sparing tool, despite its discriminative value decreased regarding complications. Thus, further studies are needed to investigate specifically surgical settings, validating the EmSFI prognostic role in assessing the procedure-related morbidity risk.

Risk Assessment in Elderly Patients Undergoing Emergency Surgery for Complicated Appendicitis: Serum Albumin More Predictive than other Indices

2014 ◽  
Vol 219 (3) ◽  
pp. S53
Author(s):  
Doris Wagner ◽  
Georg Werkgartner ◽  
Johann Pfeiffer ◽  
Regina Elisabeth Roller ◽  
Mathias Wagner ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Elderly Patients ◽  
Serum Albumin ◽  
Emergency Surgery ◽  
Complicated Appendicitis
Sign in / Sign up

Export Citation Format

Share Document