scholarly journals Within and between person effects of sleep quality on daily cognitive performance: Data from the Einstein Aging Study (EAS)

2020 ◽  
Vol 16 (S10) ◽  
Author(s):  
Carol A Derby ◽  
Ruixue Zhaoyang ◽  
June L Jiao ◽  
Martin J Sliwinski ◽  
Orfeu M Buxton
Keyword(s):  
Sleep Quality ◽  
Cognitive Performance ◽  
Performance Data ◽  
Aging Study

scholarly journals Actigraphic Measures of Sleep Quality Associated With Ambulatory Cognitive Performance in Older Adults

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 578-578
Author(s):  
Orfeu Buxton ◽  
Ruixue Zhaoyang ◽  
June Jiao ◽  
Rachel Zimmerman ◽  
Martin Sliwinski ◽  
...  
Keyword(s):  
Sleep Quality ◽  
Response Time ◽  
Cognitive Performance ◽  
Sleep Onset ◽  
Study Cohort ◽  
Learning Effects ◽  
Community Based ◽  
Shape Accuracy ◽  
Error Proportion ◽  
Aging Study

Abstract Few longitudinal studies link objectively assessed sleep and cognitive performance in ecologically-valid environments. Participants enrolled in the community-based Einstein Aging Study cohort (n=224, M[age]=77.17). Wake after sleep onset (WASO) was associated with worse cognitive performance with and without MCI (2-week smartphone-based EMA, six assessments/day). Models include age, gender, ethnicity, education, learning effects, sleep duration, WASO*MCI interaction (p=0.015 for Symbol Match; p=0.002 for Color Shape). Associations were stronger among those with MCI, thirty minutes more nightly WASO predicted a 500ms longer Symbol Match response time (p<0.0001), 5.05% higher Color Dot error proportion (p=0.002), 0.184 points lower Color Shape accuracy (p<0.0001). In those without MCI, WASO was associated with worse cognition: thirty minutes more nightly WASO predicted +166.7ms Symbol Match response time (p=0.03) and -0.06 points Color Shape accuracy (p=0.013). Actigraphic sleep quality associated with ambulatory cognitive performance (and worse with MCI status) suggests targets for prevention/mitigation of cognitive decline. Part of a symposium sponsored by the Sleep, Circadian Rhythms and Aging Interest Group.

Sleep symptomatology is associated with greater subjective cognitive concerns: Findings from the community-based Healthy Brain Project

SLEEP ◽  
2021 ◽  
Author(s):  
Jessica Nicolazzo ◽  
Katharine Xu ◽  
Alexandra Lavale ◽  
Rachel Buckley ◽  
Nawaf Yassi ◽  
...  
Keyword(s):  
Cognitive Function ◽  
Sleep Quality ◽  
Cognitive Performance ◽  
Sex Education ◽  
Severity Index ◽  
Analysis Of Covariance ◽  
Psychomotor Function ◽  
Community Based ◽  
The Relationship ◽  
Insomnia Severity

Abstract Study objectives To examine if sleep symptomatology was associated with subjective cognitive concerns or objective cognitive performance in a dementia-free community-based sample. Methods A total of 1421 middle-aged participants (mean±standard deviation = 57±7; 77% female) from the Healthy Brain Project completed the Pittsburgh Sleep Quality Index (PSQI), Insomnia Severity Index (ISI), and Epworth Sleepiness Scale (ESS) to measure sleep quality, insomnia symptom severity, and daytime sleepiness, respectively. Participants were classified as having no sleep symptomatology (normal scores on each sleep measure), moderate sleep symptomatology (abnormal scores on one sleep measure), or high sleep symptomatology (abnormal scores on at least two sleep measures), using established cut-off values. Analysis of covariance was used to compare objective cognitive function (Cogstate Brief Battery) and subjective cognitive concerns (Modified Cognitive Function Instrument) across groups. Results Following adjustments for age, sex, education, mood, and vascular risk factors, persons classified as having high sleep symptomatology, versus none, displayed more subjective cognitive concerns (d=0.24) but no differences in objective cognitive performance (d=0.00-0.18). Subjective cognitive concerns modified the association between sleep symptomatology and psychomotor function. The strength of the relationship between high sleep symptomatology (versus none) and psychomotor function was significantly greater in persons with high as compared with low cognitive concerns (β±SE =-0.37±0.16; p=0.02). Conclusions More severe sleep symptomatology was associated with greater subjective cognitive concerns. Persons reporting high levels of sleep symptomatology may be more likely to display poorer objective cognitive function in the presence of subjective cognitive concerns.

P1-209: Cerebral amyloid angiopathy is not associated with late-life cognitive performance in the honolulu asia aging study

2015 ◽  
Vol 11 (7S_Part_9) ◽  
pp. P430-P431
Author(s):  
Steven D. Edland ◽  
Rebecca Gelber ◽  
Chris Zarow ◽  
Jane Uyehara-Lock ◽  
Joshua Sonnen ◽  
...  
Keyword(s):  
Cognitive Performance ◽  
Cerebral Amyloid Angiopathy ◽  
Late Life ◽  
Amyloid Angiopathy ◽  
Aging Study ◽  
Cerebral Amyloid

scholarly journals Intensity dependent effect of cognitive training on motor cortical plasticity and cognitive performance in humans

2020 ◽  
Vol 238 (12) ◽  
pp. 2805-2818
Author(s):  
Christina Berns ◽  
Wanja Brüchle ◽  
Sebastian Scho ◽  
Jessica Schneefeld ◽  
Udo Schneider ◽  
...  
Keyword(s):  
Physical Activity ◽  
Sleep Quality ◽  
Cognitive Performance ◽  
Cognitive Training ◽  
Activity Concentration ◽  
Cortical Plasticity ◽  
Cognitive System ◽  
Brain Areas ◽  
Motor Excitability ◽  
Motor Cortical

Abstract Intervention-induced neuroplastic changes within the motor or cognitive system have been shown in the human brain. While cognitive and motor brain areas are densely interconnected, it is unclear whether this interconnectivity allows for a shared susceptibility to neuroplastic changes. Using the preparation for a theoretical exam as training intervention that primarily engages the cognitive system, we tested the hypothesis whether neuroplasticity acts across interconnected brain areas by investigating the effect on excitability and synaptic plasticity in the motor cortex. 39 healthy students (23 female) underwent 4 weeks of cognitive training while revision time, physical activity, concentration, fatigue, sleep quality and stress were monitored. Before and after cognitive training, cognitive performance was evaluated, as well as motor excitability using transcranial magnetic stimulation and long-term-potentiation-like (LTP-like) plasticity using paired-associative-stimulation (PAS). Cognitive training ranged individually from 1 to 7 h/day and enhanced attention and verbal working memory. While motor excitability did not change, LTP-like plasticity increased in an intensity-depending manner: the longer the daily revision time, the smaller the increase of neuroplasticity, and vice versa. This effect was not influenced by physical activity, concentration, fatigue, sleep quality or stress. Motor cortical plasticity is strengthened by a behavioural intervention that primarily engages cognitive brain areas. We suggest that this effect is due to an enhanced susceptibility to LTP-like plasticity, probably induced by heterosynaptic activity that modulates postsynaptic excitability in motorcortical neurones. The smaller increase of PAS efficiency with higher cognitive training intensity suggests a mechanism that balances and stabilises the susceptibility for synaptic potentiation.

scholarly journals Intakes of (n-3) Fatty Acids and Fatty Fish Are Not Associated with Cognitive Performance and 6-Year Cognitive Change in Men Participating in the Veterans Affairs Normative Aging Study

2009 ◽  
Vol 139 (12) ◽  
pp. 2329-2336 ◽  
Author(s):  
Ondine van de Rest ◽  
Avron Spiro ◽  
Elizabeth Krall-Kaye ◽  
Johanna M. Geleijnse ◽  
Lisette C. P. G. M. de Groot ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Cognitive Performance ◽  
Cognitive Change ◽  
Veterans Affairs ◽  
Fatty Fish ◽  
Normative Aging Study ◽  
Aging Study ◽  
Normative Aging
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