scholarly journals Quantitative 3D analysis of the canal network in cortical bone by micro-computed tomography

2003 ◽  
Vol 274B (1) ◽  
pp. 169-179 ◽  
Author(s):  
D.M.L. Cooper ◽  
A.L. Turinsky ◽  
C.W. Sensen ◽  
B. Hallgrímsson
Keyword(s):  
Computed Tomography ◽  
Cortical Bone ◽  
3D Analysis ◽  
Micro Computed Tomography ◽  
Canal Network

scholarly journals 3D analysis of chondron morphology of human and rat articular cartilage from micro-computed tomography

2016 ◽  
Vol 24 ◽  
pp. S298 ◽  
Author(s):  
I. Kestilä ◽  
M.A. Finnilä ◽  
S.S. Karhula ◽  
L. Rieppo ◽  
P. Lehenkari ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Articular Cartilage ◽  
3D Analysis ◽  
Micro Computed Tomography

Contrast-enhanced micro-computed tomography of fatigue microdamage accumulation in human cortical bone

Bone ◽  
2011 ◽  
Vol 48 (3) ◽  
pp. 443-450 ◽  
Author(s):  
Matthew D. Landrigan ◽  
Jiliang Li ◽  
Travis L. Turnbull ◽  
David B. Burr ◽  
Glen L. Niebur ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Cortical Bone ◽  
Micro Computed Tomography ◽  
Human Cortical Bone ◽  
Contrast Enhanced ◽  
Microdamage Accumulation ◽  
Fatigue Microdamage

scholarly journals 3D micro-computed tomography of trabecular and cortical bone architecture with application to a rat model of immobilisation osteoporosis

2000 ◽  
Vol 38 (3) ◽  
pp. 326-332 ◽  
Author(s):  
A. Laib ◽  
O. Barou ◽  
L. Vico ◽  
M. H. Lafage-Proust ◽  
C. Alexandre ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Cortical Bone ◽  
Rat Model ◽  
Bone Architecture ◽  
Micro Computed Tomography

Three-dimensional analysis of cortical bone structure using X-ray micro-computed tomography

2004 ◽  
Vol 339 (1-2) ◽  
pp. 125-130 ◽  
Author(s):  
A.C. Jones ◽  
A.P. Sheppard ◽  
R.M. Sok ◽  
C.H. Arns ◽  
A. Limaye ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Cortical Bone ◽  
Dimensional Analysis ◽  
Bone Structure ◽  
Three Dimensional ◽  
Micro Computed Tomography ◽  
X Ray

Fatigue Microdamage in Bovine Cortical Bone Imaged by Micro-Computed Tomography Using a Barium Sulfate Contrast Agent

2005 ◽  
Vol 898 ◽  
Author(s):  
Huijie Leng ◽  
Xiang Wang ◽  
Glen L Niebur ◽  
Ryan K Roeder
Keyword(s):  
Computed Tomography ◽  
Contrast Agent ◽  
Cortical Bone ◽  
Barium Sulfate ◽  
Spatial Density ◽  
Distinct Region ◽  
Micro Ct ◽  
Micro Computed Tomography ◽  
Microdamage Accumulation ◽  
Notch Tip

AbstractAccumulation of microdamage during fatigue can lead to increased fracture susceptibility in bone. Current techniques for imaging microdamage in bone are inherently destructive and two-dimensional. A non-destructive, three-dimensional technique is needed to measure the spatial density of microdamage accumulation. Therefore, the objective of this study was to image microdamage accumulation in cortical bone during fatigue using micro-computed tomography (micro-CT) with a barium sulfate (BaSO4) contrast agent. Bovine cortical bone beams were loaded under four-point bending fatigue. Two symmetric notches were machined on the tensile surface in order to generate damage at the stress concentrations during loading. Specimens were loaded to a specified number of cycles or until one notch fractured, such that the other notch exhibited accumulated microdamage just prior to fracture. Microdamage ahead of the notch was stained by precipitation of BaSO4 and imaged using micro-CT. Reconstructed images showed a distinct region of bright voxels around the notch tip or along propagating cracks due to the presence of BaSO4, which was verified by backscattered electron imaging and energy dispersive spectroscopy. The stained region exhibited a characteristic kidney shape perpendicular to the notch tip, which was correlated to principal strain contours calculated by finite element analysis. The area of stained regions was positively correlated with the number of loading cycles.

scholarly journals The use of high-resolution computed tomography to explore age-related trabecular change in human ribs

2021 ◽  
Author(s):  
Sophia Mavroudas ◽  
Victoria M Dominguez
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Trabecular Bone ◽  
Cortical Bone ◽  
Volume Fraction ◽  
Bone Volume ◽  
3D Analysis ◽  
High Resolution Computed Tomography ◽  
Trabecular Thickness ◽  
Age Related

High-resolution computed tomography was used to explore age-related trabecular change in male human ribs ranging in age from 20–95 years (Mean=55 years, SD=21.634 years) from the Texas State Donated Skeletal Collection (TXSTDSC). Two regions of interest (ROIs), midshaft (50%) and anterior (75%) were extracted from each scan to analyze age-related trabecular change. Dragonfly V4.1 was used to isolate cortical bone volumes of interest (VOIs) and three trabecular VOIs for each ROI; one each along the cutaneous cortex, the center of the medullary cavity, and the pleural cortex. Each trabecular VOI was analyzed for bone volume fraction (BV/TV), trabecular thickness (TbTh), trabecular spacing (TbSp), connectivity density (Conn.D), and degree of anisotropy (DA), within and between the 50 and 75% ROIs. Overall, the cutaneous VOIs at both the 50% and 75% ROIs exhibited greater BV/TV, TbTh, and Conn.D when compared to the center and pleural VOIs. All results are consistent with expected biomechanical strain on human ribs. Both trabecular variables and cortical bone volume are only weakly associated with age. These results show that 3D analysis of trabecular bone volume does not improve visualization or understanding of trabecular bone changes with age over traditional 2D methods. Future research should incorporate female samples to explore sex-related trabecular change variation.

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