scholarly journals Cognitive deficit is correlated with sleep stability in insomnia: A cardiopulmonary coupling study

2021 ◽  
Author(s):  
Xuan Zhang ◽  
Bingxin Song ◽  
Yanyan Liu ◽  
Yahui Wan ◽  
Kaili Zhou ◽  
...  
Keyword(s):  
Cognitive Deficit ◽  
Cardiopulmonary Coupling

Dementia, Cognitive Deficit, Headache? Think Parasitic Infection of the Brain

2008 ◽  
Vol 38 (11) ◽  
pp. 36
Author(s):  
AMY ROTHMAN SCHONFELD
Keyword(s):  
Cognitive Deficit ◽  
Parasitic Infection ◽  
The Brain

Intelligence Quotient and Cognitive Fatigue are Independent Predictors of Cognitive Deficit in Pediatric MS Patients

2019 ◽  
Author(s):  
Karin Storm van’s Gravesande ◽  
Lena Haarmann ◽  
Pasquale Calabrese ◽  
Astrid Blaschek ◽  
Keven Rostasy ◽  
...  
Keyword(s):  
Intelligence Quotient ◽  
Cognitive Deficit ◽  
Cognitive Fatigue

Postoperative cognitive dysfunction: progress mechanisms and clinical characteristics

2019 ◽  
Vol 2 (19) ◽  
pp. 29-33
Author(s):  
K. B. Manysheva ◽  
M. A. Akhmedov ◽  
A. A. Rakhmanova ◽  
S. M. Khutalieva
Keyword(s):  
Cognitive Dysfunction ◽  
Clinical Characteristics ◽  
Cognitive Deficit ◽  
Neuropsychological Testing ◽  
Postoperative Cognitive Dysfunction ◽  
Clinical Manifestations ◽  
Postoperative Recovery ◽  
Neuropsychological Rehabilitation ◽  
Brain Barrier Permeability ◽  
The Central Nervous System

The article is devoted to the study of postoperative cognitive dysfunction — a syndrome that is often found in the postoperative period and does not depend on the volume of surgeon. Based on the analysis of the results of modern studies, the authors cite the most likely etiological causes of the syndrome, grouped according to different categories of risk factors. The pathogenetic algorithm for cognitive dysfunction includes the appearance of systemic inflammation, improving blood-brain barrier permeability with the endothelial dysfunction, the migration of inflammatory agents into the central nervous system, and the formation of oxidative stress. The clinical manifestations of cognitive deficit in the outcome of surgeon performed under general anesthesia, the authors illustrate with their own observations of patients with a neurosurgical profile with spinal pathology operated on with the use of propofol anesthesia, comparing the results of neuropsychological testing with an assessment of the level of anxiety. In conclusion, the authors outline a strategy for the prevention of postoperative cognitive dysfunction and recommend conducting neuropsychological rehabilitation as an important component of postoperative recovery for all patients with a diagnosed cognitive deficit that occurred after surgery.

NSC23766, A Specific Inhibitor of Rac1 GTPase, Attenuated Delayed Neuronal Cell Death and Cognitive Deficit in Rats with Cardiac Arrest

2015 ◽  
Vol 2 (3) ◽  
pp. 136-145
Author(s):  
Juan Liao ◽  
Chang Xu ◽  
Chang Liu ◽  
Na Wang ◽  
Guo-Qing Huang ◽  
...  
Keyword(s):  
Cell Death ◽  
Cardiac Arrest ◽  
Cognitive Deficit ◽  
Neuronal Cell Death ◽  
Specific Inhibitor ◽  
Neuronal Cell ◽  
Rac1 Gtpase ◽  
Delayed Neuronal Cell Death

Cannabinoid Receptor Type 1 Agonist ACEA Improves Cognitive Deficit on STZ-Induced Neurotoxicity Through Apoptosis Pathway and NO Modulation

2019 ◽  
Vol 35 (3) ◽  
pp. 516-529 ◽  
Author(s):  
Fernanda Crunfli ◽  
Talita A. Vrechi ◽  
Andressa P. Costa ◽  
Andréa S. Torrão
Keyword(s):  
Cognitive Deficit ◽  
Cannabinoid Receptor ◽  
Receptor Type ◽  
Apoptosis Pathway ◽  
Cannabinoid Receptor Type 1

Stem cell restores thalamocortical plasticity to rescue cognitive deficit in neonatal intraventricular hemorrhage

2021 ◽  
pp. 113736
Author(s):  
So Yoon Ahn ◽  
Hyesoo Jie ◽  
Won-Beom Jung ◽  
Ji-Hyun Jeong ◽  
Sukjin Ko ◽  
...  
Keyword(s):  
Stem Cell ◽  
Intraventricular Hemorrhage ◽  
Cognitive Deficit

scholarly journals Cardiopulmonary coupling indices to assess weaning readiness from mechanical ventilation

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Pablo Armañac-Julián ◽  
David Hernando ◽  
Jesús Lázaro ◽  
Candelaria de Haro ◽  
Rudys Magrans ◽  
...  
Keyword(s):  
Heart Rate ◽  
Mechanical Ventilation ◽  
Spontaneous Breathing Trial ◽  
Sinus Arrhythmia ◽  
Time Frequency ◽  
Cardiopulmonary Coupling ◽  
Cardiac Pumping ◽  
Successful Weaning ◽  
Frequency Coherence ◽  
Subspace Projections

AbstractThe ideal moment to withdraw respiratory supply of patients under Mechanical Ventilation at Intensive Care Units (ICU), is not easy to be determined for clinicians. Although the Spontaneous Breathing Trial (SBT) provides a measure of the patients’ readiness, there is still around 15–20% of predictive failure rate. This work is a proof of concept focused on adding new value to the prediction of the weaning outcome. Heart Rate Variability (HRV) and Cardiopulmonary Coupling (CPC) methods are evaluated as new complementary estimates to assess weaning readiness. The CPC is related to how the mechanisms regulating respiration and cardiac pumping are working simultaneously, and it is defined from HRV in combination with respiratory information. Three different techniques are used to estimate the CPC, including Time-Frequency Coherence, Dynamic Mutual Information and Orthogonal Subspace Projections. The cohort study includes 22 patients in pressure support ventilation, ready to undergo the SBT, analysed in the 24 h previous to the SBT. Of these, 13 had a successful weaning and 9 failed the SBT or needed reintubation –being both considered as failed weaning. Results illustrate that traditional variables such as heart rate, respiratory frequency, and the parameters derived from HRV do not differ in patients with successful or failed weaning. Results revealed that HRV parameters can vary considerably depending on the time at which they are measured. This fact could be attributed to circadian rhythms, having a strong influence on HRV values. On the contrary, significant statistical differences are found in the proposed CPC parameters when comparing the values of the two groups, and throughout the whole recordings. In addition, differences are greater at night, probably because patients with failed weaning might be experiencing more respiratory episodes, e.g. apneas during the night, which is directly related to a reduced respiratory sinus arrhythmia. Therefore, results suggest that the traditional measures could be used in combination with the proposed CPC biomarkers to improve weaning readiness.

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