scholarly journals Waist circumference and a body shape index and prostate cancer risk and mortality

2021 ◽  
Author(s):  
Sylvia H. J. Jochems ◽  
Angela M. Wood ◽  
Christel Häggström ◽  
Marju Orho‐Melander ◽  
Pär Stattin ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Waist Circumference ◽  
Cancer Risk ◽  
Body Shape ◽  
Prostate Cancer Risk ◽  
Shape Index ◽  
A Body Shape Index

Original Article (Clinical Investigation) Enhanced Prediction of Renal Function Decline by Replacing Waist Circumference With “a Body Shape Index (Absi)” in Diagnosing Metabolic Syndrome: A Retrospective Cohort Study in Japan

2021 ◽  
Author(s):  
Daiji Nagayama ◽  
Kentaro Fujishiro ◽  
Shinichi Tsuda ◽  
Yasuhiro Watanabe ◽  
Takashi Yamaguchi ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Renal Function ◽  
Cohort Study ◽  
Waist Circumference ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Body Shape ◽  
Shape Index ◽  
Renal Function Decline ◽  
A Body Shape Index

Abstract Background: Abdominal obesity as a risk factor for diagnosing metabolic syndrome (MetS) is conventionally evaluated using waist circumference (WC), although WC does not necessarily reflect visceral adiposity. We aimed to examine whether replacing WC with “A Body Shape Index (ABSI)”, an abdominal obesity index, in MetS diagnosis is useful for predicting renal function decline (RFD). Methods: A retrospective cohort study was conducted in 5438 Japanese urban residents (median age 48 years) who participated in a public health screening program for 4 consecutive years. Systemic arterial stiffness was assessed by cardio-ankle vascular index (CAVI), and high CAVI was defined as CAVI ≥ 9.0. The predictability of the occurrence of RFD (eGFR < 60 mL/min/1.73m 2 ) by replacing high WC with high ABSI (ABSI ≥ 0.080) was examined using three sets of MetS diagnostic criteria: Japanese, International Diabetes Federation (IDF) and National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATPIII). Results: In Japanese and NCEP-ATPIII criteria, MetS diagnosed using ABSI (ABSI-MetS) was associated with significantly higher age-adjusted CAVI compared to non-MetS, whereas MetS diagnosed using WC (WC-MetS) showed no association. Kaplan-Meier analysis of the rate of new-onset RFD over 4 years (total 8.7%) showed remarkable higher rate in subjects with ABSIMetS than in those without (log-rank test p <0.001), but almost no difference between subjects with and without WC-MetS ( p = 0.014-0.617). In Cox analysis including gender, high CAVI and low-density lipoprotein‒cholesterol ≥140 mg/dL as confounders, only ABSI-MetS diagnosed by Japanese criteria contributed independently to the occurrence of RFD (HR = 1.41, p = 0.011). High CAVI was also an independent contributor to the occurrence of RFD. In a subanalysis, ABSI-MetS diagnosed by Japanese criteria contributed significantly to the occurrence of RFD regardless of age or gender, while WC-MetS by Japanese criteria contributed significantly only in older women. Conclusion: In this study, replacing WC with ABSI in MetS diagnostic criteria more efficiently predicted subjects at risk of RFD and arterial stiffening. Further studies are needed to confirm whether MetS diagnosed using ABSI also predicts CVD.

scholarly journals Does increased body mass index lead to elevated prostate cancer risk? It depends on waist circumference

BMC Cancer ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Jin Bong Choi ◽  
Jun-Pyo Myong ◽  
Yunhee Lee ◽  
Inah Kim ◽  
Jung Ho Kim ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Body Mass Index ◽  
Waist Circumference ◽  
Cancer Risk ◽  
Body Mass ◽  
Prostate Cancer Risk

scholarly journals Enhanced prediction of renal function decline by replacing waist circumference with “A Body Shape Index (ABSI)” in diagnosing metabolic syndrome: a retrospective cohort study in Japan

2021 ◽  
Author(s):  
Daiji Nagayama ◽  
Kentaro Fujishiro ◽  
Shinichi Tsuda ◽  
Yasuhiro Watanabe ◽  
Takashi Yamaguchi ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Renal Function ◽  
Waist Circumference ◽  
Diagnostic Criteria ◽  
Abdominal Obesity ◽  
Body Shape ◽  
Shape Index ◽  
Renal Function Decline ◽  
A Body Shape Index ◽  
New Onset

Abstract Background Abdominal obesity as a risk factor for diagnosing metabolic syndrome (MetS) is conventionally evaluated using waist circumference (WC), although WC does not necessarily reflect visceral adiposity. Objective To examine whether replacing WC with “A Body Shape Index (ABSI)”, an abdominal obesity index calculated by dividing WC by an allometric regression of weight and height, in MetS diagnosis is useful for predicting renal function decline. Subjects/Methods In total, 5438 Japanese urban residents (median age 48 years) who participated in a public health screening program for 4 consecutive years were enrolled. Systemic arterial stiffness was assessed by cardio-ankle vascular index (CAVI). The predictability of the new-onset renal function decline (eGFR < 60 mL/min/1.73 m2) by replacing high WC with high ABSI (ABSI ≥ 0.080) was examined using three sets of MetS diagnostic criteria: Japanese, IDF and NCEP-ATPIII. Results In Japanese and NCEP-ATPIII criteria, MetS diagnosed using ABSI (ABSI-MetS) was associated with significantly higher age-adjusted CAVI compared to non-MetS, whereas MetS diagnosed using WC (WC-MetS) showed no association. Kaplan–Meier analysis of the rate of new-onset renal function decline over 4 years (total 8.7%) showed remarkable higher rate in subjects with ABSI-MetS than in those without (log-rank test p < 0.001), but almost no difference between subjects with and without WC-MetS (p = 0.014–0.617). In gender-specific Cox-proportional hazards analyses including age, proteinuria, and treatments of metabolic disorders as confounders, ABSI-MetS (Japanese criteria for both sexes, IDF criteria for men) contributed independently to the new-onset renal function decline. Of these, the contribution of IDF ABSI-MetS disappeared after adjustment by high CAVI in the subsequent analysis. Conclusion In this study, replacing WC with ABSI in MetS diagnostic criteria more efficiently predicted subjects at risk of renal function decline and arterial stiffening.

Abstract MP64: Body Mass Index and Waist Circumference are More Strongly Associated with Abdominal Adiposity Compared to a Body Shape Index in Middle-aged Adults: The Cardia Study

Circulation ◽  
2013 ◽  
Vol 127 (suppl_12) ◽  
Author(s):  
Michael Machiorlatti ◽  
Christina M Shay ◽  
David Jacobs ◽  
Cora E Lewis ◽  
James Lovato ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Waist Circumference ◽  
Body Shape ◽  
Shape Index ◽  
Abdominal Adiposity ◽  
Black And White ◽  
Additional Information ◽  
Middle Aged Adults ◽  
Clinical Measures ◽  
A Body Shape Index

Background: A Body Shape Index (ABSI) has been recently shown to better predict mortality when compared to BMI and waist circumference. Although individuals with higher abdominal adiposity generally exhibit greater mortality risk, the association between ABSI and imaging-based measures of abdominal adiposity has not been thoroughly explored. Objective: To quantify and compare associations between ABSI, BMI, and waist circumference with computed-tomography assessed measures of visceral (VAT), subcutaneous (SAT), and total (TAT) abdominal adipose tissue volumes in middle age adults according to race and sex. Methods: Coronary Artery Risk Development in Young Adults (CARDIA) is a community-based, prospective study of black and white men and women. Height (cm), weight (kg), and waist circumference (WC) were assessed during the year 25 exam (43-55 yrs), from which, BMI (kg/m 2 ) and A Body Shape Index (ABSI) were calculated. VAT, SAT, and TAT volumes (cm 3 ) were concurrently measured by computed tomography (n=3,155). Linear regression was used to assess the amount of variation in VAT, SAT and TAT explained by BMI, WC and ABSI composition measure accounting for age, sex, race, and study center Results: Height, weight, BMI, WC and ABSI were all univariately associated with VAT, SAT and TAT with significant interactions by race and sex. Across all race/sex groups, BMI, WC and weight explained greater variance in VAT, SAT and TAT compared to ABSI (Table 1). WC generally explained the most variance in abdominal adiposity measures (R 2 =0.56-0.74). BMI explained the largest amount of variance in SAT (R 2 = 0.74-0.78). ABSI and height explained the least variance in abdominal adiposity (range R 2 < 0.29). Conclusions: Although ABSI may provide additional information related to mortality that is not explained by more simple anthropometric measurements, the associations reported may not be strongly mediated through abdominal adiposity. BMI and WC remain simple clinical measures that strongly account for variations in abdominal adiposity.

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