Structural Exploration of Multilayered Ionic Liquid/Ag Electrode Interfaces by Atomic Force Microscopy and Surface‐Enhanced Raman Spectroscopy

In the present study, we propose a novel biosensor platform using a gold-tellurium (Au–Te) nanoworm structure through surface-enhanced Raman spectroscopy (SERS). Au–Tenanoworm was synthesized by spontaneous galvanic replacement of sacrificial Te nanorods templated with Au (III) cations under ambient conditions. The fabricated Au–Te nanoworm exhibited an interconnected structure of small spherical nanoparticles and was found to be effective at enhancing Raman scattering. The Au–Te nanoworm-immobilized substrate exhibited the ability to detect thyroxine using an aptamer-tagged DNA three-way junction (3WJ) and glycoprotein 120 (GP120) human immunodeficiency virus (HIV) using an antibody. The modified substrates were investigated by scanning electron microscopy and atomic force microscopy (AFM). The optimal Au–Te nanoworm concentration and immobilization time for the thyroxine biosensor platform were further determined by SERS experimentation. Thus, the present study showed that the Au–Te nanoworm structure could be applied to various biosensor platforms.

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Detection of Ultra-Low Concentration of Chiral (R)-di-2-Naphthylprolinol on Ag-Nanoparticles-Modified Ag Electrode by Surface-Enhanced Raman Spectroscopy

ECS Meeting Abstracts ◽

10.1149/ma2010-01/37/1708 ◽

2010 ◽

Keyword(s):

Raman Spectroscopy ◽

Ag Nanoparticles ◽

Surface Enhanced Raman Spectroscopy ◽

Low Concentration ◽

Ag Electrode ◽

Surface Enhanced ◽

Surface Enhanced Raman

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Surface-Enhanced Raman Scattering and Atomic Force Microscopy of Brass Electrodes in Sulfuric Acid Solution Containing Benzotriazole and Chloride Ion

Applied Spectroscopy ◽

10.1366/0003702934048541 ◽

1993 ◽

Vol 47 (1) ◽

pp. 80-84 ◽

Cited By ~ 4

Author(s):

Joel C. Rubim ◽

Jae-Ho Kim ◽

Eric Henderson ◽

Therese M. Cotton

Keyword(s):

Atomic Force Microscopy ◽

Sulfuric Acid ◽

Raman Scattering ◽

Acid Solution ◽

Chloride Ion ◽

Force Microscopy ◽

Atomic Force ◽

Surface Enhanced ◽

Surface Enhanced Raman ◽

Enhanced Raman Scattering

Three different methods were used to roughen brass (Cu/Zn = 67/33) electrodes in 0.5 M H2SO4 containing 1.0 mM benzotriazole (BTAH): (1) polarization at +0.05 V vs. saturated calomel for 5 min; (2) immersion in the above solution for six hours; and (3) oxidation-reduction cycling in the presence of chloride ion. The surfaces prepared by the first two methods exhibited surface-enhanced Raman scattering (SERS) spectra of the polymeric complex [Cu(I)BTA] n. The SERS spectrum obtained from electrodes prepared by the third method is very similar to that of [CU(I)C1BTAH]4. Examination of the electrodes by atomic force microscopy (AFM) showed that a large number of grain boundary sites are formed by the roughening processes. This effect is attributed to the loss of zinc, which occurs during corrosion of the mirror-like, polished brass electrode surface in the sulfuric acid solution.

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