ChemInform Abstract: Fluorine Containing Amino Acids. Part 4. Synthesis and Biological Activity of β-(Polyfluoromethyl)-Substituted Aromatic Amino Acids.

ChemInform ◽  
1988 ◽  
Vol 19 (34) ◽  
Author(s):  
M. T. KOLYCHEVA ◽  
YU. L. YAGUPOL'SKII ◽  
L. M. ZAITSEV ◽  
I. I. GERUS ◽  
V. P. KUKHAR' ◽  
...  
Keyword(s):  
Amino Acids ◽  
Biological Activity ◽  
Aromatic Amino Acids

Fluorine-containing amino acids. IV. Synthesis and biological activity of ?-polyfluoromethyl-substituted aromatic amino acids

1988 ◽  
Vol 22 (2) ◽  
pp. 110-114 ◽  
Author(s):  
M. T. Kolycheva ◽  
Yu. L. Yagupol'skii ◽  
L. M. Zaitsev ◽  
I. J. Gerus ◽  
V. P. Kukhar' ◽  
...  
Keyword(s):  
Amino Acids ◽  
Biological Activity ◽  
Aromatic Amino Acids

scholarly journals Self-assembly and biological activities of ionic liquid crystals derived from aromatic amino acids

2018 ◽  
Vol 20 (31) ◽  
pp. 20371-20381 ◽  
Author(s):  
Manuel M. Neidhardt ◽  
Katharina Schmitt ◽  
Angelika Baro ◽  
Carmen Schneider ◽  
Ursula Bilitewski ◽  
...  
Keyword(s):  
Amino Acids ◽  
Ionic Liquid ◽  
Biological Activity ◽  
Liquid Crystals ◽  
Amino Acid ◽  
Self Assembly ◽  
Biological Activities ◽  
Aromatic Amino Acids ◽  
Ionic Liquid Crystals

Does the mesomorphic behaviour of l-amino acid-based ILCs correlate with biological activity?

scholarly journals Effect of phenolic compounds on nematodes- A review

2010 ◽  
Vol 2 (2) ◽  
pp. 344-350 ◽  
Author(s):  
Puja Ohri ◽  
Satinder Kaur Pannu
Keyword(s):  
Amino Acids ◽  
Biological Activity ◽  
Phenolic Compounds ◽  
Secondary Metabolites ◽  
Plant Pathogens ◽  
Plant Secondary Metabolites ◽  
Aromatic Amino Acids ◽  
Common Mechanism ◽  
Phenolic Substances ◽  
Diverse Plant

The term, phenolics has been used to describe a group of structurally diverse plant secondary metabolites. This group includes metabolites derived from the condensation of acetate units (terpenoids), those produced by the modification of aromatic amino acids (phenylpropanoids, cinnamic acid, lignin precursor, catechols and coumarins), flavonoids, isoflavonoids, and tannins. The occurrence and metabolism of phenolic substances in plants, in response to injury or invasion by pathogens, such as fungi, bacteria and viruses have already been studied. Oxidised compounds produced in plants after invasion by pathogens often show considerable biological activity and are a common mechanism of resistance to plant pathogens. The present review gives information regarding the effects of different phenolic compounds on nematode system. It is found that these compounds are involved in plant defense and hence provide resistance against nematode attack.

The Efficient Preparation of Radiolabeled Aromatic Amino Acids via Cu-Mediated Radiofluorination using Ni-complexes

2019 ◽  
Author(s):  
A Craig ◽  
N Kolks ◽  
E Urusova ◽  
BD Zlatopolskiy ◽  
B Neumaier
Keyword(s):  
Amino Acids ◽  
Aromatic Amino Acids

Long term dietary intake of aromatic amino acids are associated with leptin gene expression in adipose tissues of non-diabetic adults

2018 ◽  
Author(s):  
Golaleh Asghari ◽  
Emad Yuzbashian ◽  
Maryam Zarkesh ◽  
Parvin Mirmiran ◽  
Mehdi Hedayati ◽  
...  
Keyword(s):  
Gene Expression ◽  
Amino Acids ◽  
Dietary Intake ◽  
Aromatic Amino Acids ◽  
Adipose Tissues

Single Amino Acid Based Self-Assemblies of Cysteine and Methionine

2018 ◽  
Author(s):  
Nidhi Gour ◽  
Bharti Koshti ◽  
Chandra Kanth P. ◽  
Dhruvi Shah ◽  
Vivek Shinh Kshatriya ◽  
...  
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Self Assembly ◽  
Aromatic Amino Acids ◽  
Neutral Condition ◽  
Single Amino Acid ◽  
Binding Assays ◽  
Human Neuroblastoma ◽  
Cytotoxicity Assays ◽  
First Time

We report for the very first time self-assembly of Cysteine and Methionine to discrenible strucutres under neutral condition. To get insights into the structure formation, thioflavin T and Congo red binding assays were done which revealed that aggregates may not have amyloid like characteristics. The nature of interactions which lead to such self-assemblies was purported by coincubating assemblies in urea and mercaptoethanol. Further interaction of aggregates with short amyloidogenic dipeptide diphenylalanine (FF) was assessed. While cysteine aggregates completely disrupted FF fibres, methionine albeit triggered fibrillation. The cytotoxicity assays of cysteine and methionine structures were performed on Human Neuroblastoma IMR-32 cells which suggested that aggregates are not cytotoxic in nature and thus, may not have amyloid like etiology. The results presented in the manuscript are striking, since to the best of our knowledge,this is the first report which demonstrates that even non-aromatic amino acids (cysteine and methionine) can undergo spontaneous self-assembly to form ordered aggregates.

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