The improvement of biocompatibility by incorporating porphyrins into carbon dots with photodynamic effects and pH sensitivities

Photodynamic therapy (PDT) is a promising new treatment for cancer; however, the hydrophobic interactions and poor solubility in water of photosensitizers limit the use in clinic. Nanoparticles especially carbon dots have attracted the attention of the world’s scientists because of their unique properties such as good solubility and biocompatibility. In this paper, we integrated carbon dots with different porphyrins to improve the properties of porphyrins and evaluated their efficacy as PDT drugs. The spectroscopic characteristics of porphyrins nano-conjugates were studied. Singlet oxygen generation rate and the light- and dark-induced toxicity of the conjugates were studied. Our results showed that the covalent interaction between CDs and porphyrins has improved the biocompatibility. The synthesized conjugates also inherit the pH sensitivity of the carbon dots, while the conjugation also decreases the hemolysis ratio making them a promising candidate for PDT. The incorporation of carbon dots into porphyrins improved their biocompatibility by reducing toxicity.

THEORETICAL STUDYING SPECTRAL CHARACTERISTICS OF Zn-LIKE IONS ON THE BASIS OF RELATIVISTIC MANY-BODY PERTURBATION THEORY

A theoretical study of the spectroscopic characteristics of Zn-like multiply charged ions is carried out within the framework of the relativistic many-body perturbation theory. The optimized Dirac-Kohn-Shem approximation was chosen as the zero approximation of the relativistic perturbation theory. Optimization has been fulfilled by means of introduction of the parameters to the Kohn-Sham exchange and correlation potentials and further minimization of the gauge-non-invariant contributions into radiation width of atomic levels with using relativistic orbital set, generated by the corresponding zeroth approximation Hamiltonian.

Boosted Electronic, NLO and Absorption Characteristics for Quercetin and Taxifolin; Comparative Experimental and DFT Studies

In the present study, a considerable, reproducible, and eco-friendly biological synthesis of Ag nanoparticles using Mangifera indica leaf extract as a reductant is documented. The spectroscopic characteristics of synthesized Ag nanoparticles are described by both UV-Vis and FT-IR techniques. The bandgap offsets, reactivity, and NLO properties for two flavonoids, quercetin, and taxifolin, are examined using the DFT approach. Also, a detailed comparative analysis for HOMO-LUMO interactions among quercetin and taxifolin is discussed. Results show that quercetin and taxifolin possess dipole moment (DM=4.79, 3.99 Debye) and bandgap offset (2.59, 2.98 eV). Both molecules are promising candidates as window layers for solar cells and memory switch devices. In addition, hyperpolarizability calculations show that quercetin NLO response is higher than taxifolin, which sets a revolutionary recall for NLO manufacture upgrade. Moreover, NBO and UV-Vis absorption characteristics are reported as well.

Fluorescence Characteristics of Highly-Pure Nanoparticles Embedded in Dye Complexes for Random Laser Design

In this work, highly-pure titanium dioxide nanoparticles produced by dc magnetron sputtering technique were embedded in organometallic complex solutions such as Baq2 or Znq2 to form random gain media. The structural characteristics of the TiO2 nanoparticles were determined to confirm their high structural purity. The spectroscopic characteristics, mainly photoluminescence and fluorescence, of the complex solutions containing the nanoparticles were determined and studied. These media were compared to two of the most common laser dyes (Rhodamine b and Rhodamine 6G) to determine the feasibility to use them to produce random laser.

Boosted Electronic, NLO and Absorption Characteristics for Quercetin and Taxifolin: Comparative Experimental and DFT Studies

In the present study, a considerable, reproducible, and eco-friendly biological synthesis of Ag nanoparticles using Mangifera indica leaf extract as a reductant is documented. The spectroscopic characteristics of synthesized Ag nanoparticles are described by both UV-Vis and FT-IR techniques. The bandgap offsets, reactivity, and NLO properties for two flavonoids, quercetin, and taxifolin, are examined using the DFT approach. Also, a detailed comparative analysis for HOMO-LUMO interactions among quercetin and taxifolin is discussed. Results show that quercetin and taxifolin possess dipole moment (DM=4.79, 3.99 Debye) and bandgap offset (2.59, 2.98 eV). Both molecules are promising candidates as window layers for solar cells and memory switch devices. In addition, hyperpolarizability calculations show that quercetin NLO response is higher than taxifolin, which sets a revolutionary recall for NLO manufacture upgrade. Moreover, NBO and UV-Vis absorption characteristics are reported as well.