Introduction:
Chitin and pectin are important natural polymers which are used as natural catalyst for synthesis of tri- and tetra- phenyl substituted 1H-imidazoles.
Material and methods:
The reaction of benzil and aromatic aldehydes with ammonium acetate in the presence of chitin produces 2,4,5-triphenyl-1H-imidazoles and the reaction of benzil, aromatic aldehydes and aniline derivatives with ammonium acetate in the presence of pectin produces 1,2,4,5-tetraphenyl-1H-imidazoles, respectively.
Results:
The results show that synthesis of 2,4,5-triphenyl-1H-imidazoles and 1,2,4,5-tetraphenyl-1H-imidazoles can be catalyzed by chitin and pectin in an effective route, respectively. All synthesized compounds are in good agreement with previously reported compounds.
Conclusion:
In conclusion, an efficient methodology has been carried out to generate 2,4,5-triphenyl-1H-imidazoles and 1,2,4,5-tetraphenyl-1H-imidazoles, by using non-toxic, cheap and in available catalysis (chitin and pectin).