Transcriptome and cytogenetic profiling analysis of matched in situ/invasive cutaneous squamous cell carcinomas from immunocompetent patients

2019 ◽  
Vol 58 (3) ◽  
pp. 164-174 ◽  
Author(s):  
Irene García-Díez ◽  
Inmaculada Hernández-Muñoz ◽  
Eugenia Hernández-Ruiz ◽  
Lara Nonell ◽  
Eulàlia Puigdecanet ◽  
...  
Pathobiology ◽  
2011 ◽  
Vol 78 (3) ◽  
pp. 171-180 ◽  
Author(s):  
Akinori Funayama ◽  
Jun Cheng ◽  
Satoshi Maruyama ◽  
Manabu Yamazaki ◽  
Takanori Kobayashi ◽  
...  

Author(s):  
Margaret M. Madeleine ◽  
Lisa G. Johnson

Vulvar and vaginal cancers are rare and predominantly involve squamous cell carcinomas. Some studies combine these cancers, presumably because of their rarity, anatomic proximity, and shared risk factors. Major risk factors include human papillomavirus (HPV) and cigarette smoking. This chapter explores the similarities and important differences in etiology between these cancer sites. In addition to its focus on invasive cancer, the chapter also discusses high-grade precursor lesions, or in situ disease, that sometimes progress to cancer and must, therefore, be treated.


2019 ◽  
Vol 8 (1) ◽  
pp. 96 ◽  
Author(s):  
Ana-Liana Tataru ◽  
Gheorghe Furau ◽  
Jompan Afilon ◽  
Cringu Ionescu ◽  
Mihai Dimitriu ◽  
...  

Romania has the highest incidence of cervical cancer morbidity and mortality in Europe. This study identifies the major clusters for genital cancers, observes the features of genital and cervical cancer, and determines the extent to which cancer is a contributor to total Disability-Adjusted Life Year (DALY). Spatial analysis used Besag and Newell’s method for genital cancer distribution, prevalence considered Arad County patients records (2008–2017), and DALY was determined according to WHO methodology and GLOBOCAN 2013 data. Diagnosis was established by histopathological examination of diagnostic biopsies or tissues obtained by surgical procedures, followed by clinical staging. 1695 women were recorded with genital cancer. Of these, 14.9% of lesions were in situ (n = 252) and 74.20% of cases were recorded in stage III or IV (n = 1258) (p < 0.0001). Over 90% of cervical cancers were squamous cell carcinomas (n = 728), 33.76% of endometrial cancers were adenocarcinomas in situ (n = 131), 32.42% of ovarian cancers were serous adenocarcinomas (n = 131), and 70.58% of vulvar cancers were squamous cell carcinomas (n = 48) (p < 0.0001). DALY/1000 was 67.2 for genital cancers and 33 for cervical cancers. From the point of view of Romanian women, cervical cancer remains one of the major problems that need to be dealt with and access to optimal treatment proves to be extremely limited.


2011 ◽  
Vol 19 (3) ◽  
pp. 239-245 ◽  
Author(s):  
Daniela Cabibi ◽  
Francesco Aragona ◽  
Carla Guarnotta ◽  
Vito Rodolico ◽  
Monica Zerilli ◽  
...  

1995 ◽  
Vol 26 (3) ◽  
pp. 251-261 ◽  
Author(s):  
Maria J Worsham ◽  
Sandra R Wolman ◽  
Thomas E Carey ◽  
Richard J Zarbo ◽  
Michael S Benninger ◽  
...  

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