scholarly journals Expanding access to hepatitis C treatment by improving linkage to care: Establishing a cascade of care and active linkage program for the South Karelia region in Finland

2020 ◽  
Vol 3 (4) ◽  
Author(s):  
Juha Kemppinen ◽  
Hanna‐Kaisa Anttila ◽  
Pekka Suomalainen ◽  
Sauli Vuoti
Keyword(s):  
Hepatitis C ◽  
Linkage To Care ◽  
The South ◽  
Hepatitis C Treatment ◽  
Cascade Of Care ◽  
Linkage Program

scholarly journals Eliminating hepatitis C on the Balearic Islands, Spain: a protocol for an intervention study to test and link people who use drugs to treatment and care

BMJ Open ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. e053394
Author(s):  
Jeffrey V Lazarus ◽  
Andrea Herranz ◽  
Camila A Picchio ◽  
Marcela Villota-Rivas ◽  
Antonia Rodríguez ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Intervention Study ◽  
Descriptive Analysis ◽  
Linkage To Care ◽  
Risk Groups ◽  
Primary Objective ◽  
Balearic Islands ◽  
People Who Use Drugs ◽  
Addiction Service ◽  
Cascade Of Care

IntroductionThe hepatitis C virus (HCV) is a highly infectious and deadly disease, affecting some 58 million people worldwide. Of the 1.13 million people living in the Balearic Islands, Spain, about 1350 individuals have untreated HCV. Of these, about 1120 (83%) are estimated to be people who use drugs (PWUD), who are one of the key at-risk groups for HCV infection globally. Carrying out micro-elimination approaches focused on this population is crucial to achieve the WHO goal of eliminating HCV by 2030. Thus, the primary objective of this study is to validate a model of care that simplifies the screening and linkage to HCV care pathways for PWUD on the Balearic Islands.Methods and analysisThis intervention study will be implemented across 17 sites, in 4 different settings: addiction service centres (n=12), non-governmental organisation centres (n=3), a mobile methadone unit and a prison, with an estimated 3725 participants. Together with the healthcare staff at each centre, the intervention protocols will be adapted, focusing on four phases: recruitment and testing; linkage to care; treatment for those who test positive; and monitoring of sustained virological response 12 weeks after treatment and reinfection. The primary outcomes will be the number of tested and treated individuals and the secondary outcomes will include individuals lost at each step in the cascade of care. Descriptive analysis and multivariable logistic regression of the data will be undertaken.Ethics and disseminationThe Hospital Clínic Barcelona, Spain, Ethics Committee approved this study on 18 February 2021 (HCB/2020/2018). Findings will be disseminated through peer-reviewed publications, conference presentations and social media. The results of this study could provide a model for targeting PWUD for HCV testing and treatment in the rest of Spain and in other settings, helping to achieve the WHO HCV elimination goal.

scholarly journals 2202. The Hepatitis C Virus Cascade of Care at Stony Brook University Hospital: Risk Factors for Linkage to Care

2018 ◽  
Vol 5 (suppl_1) ◽  
pp. S650-S650
Author(s):  
Audun Lier ◽  
Kalie Smith ◽  
Silvia Bronson ◽  
Teresa Khoo ◽  
Kerim Odekon ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Linkage To Care ◽  
University Hospital ◽  
Cascade Of Care

Time matters: Point of care screening and streamlined linkage to care dramatically improves hepatitis C treatment uptake in prisoners in England

2020 ◽  
Vol 75 ◽  
pp. 102608 ◽  
Author(s):  
Zameer Mohamed ◽  
Deyaa Al-Kurdi ◽  
Margaret Nelson ◽  
Yusuke Shimakawa ◽  
Nowlan Selvapatt ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Point Of Care ◽  
Linkage To Care ◽  
Hepatitis C Treatment ◽  
Treatment Uptake

scholarly journals The Cascade of Care for an Australian Community-Based Hepatitis C Treatment Service

PLoS ONE ◽  
2015 ◽  
Vol 10 (11) ◽  
pp. e0142770 ◽  
Author(s):  
Amanda J. Wade ◽  
Diana M. Macdonald ◽  
Joseph S. Doyle ◽  
Adam Gordon ◽  
Stuart K. Roberts ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Treatment Service ◽  
Community Based ◽  
Hepatitis C Treatment ◽  
Cascade Of Care ◽  
Australian Community

scholarly journals Linkage to Care for Hepatitis C: Creating a Cascade of Care to Identify Gaps at the Individual Hospital Level

2015 ◽  
Vol 2 (suppl_1) ◽  
Author(s):  
Asher Schranz ◽  
Jason Halperin ◽  
Andrea Liu ◽  
Henry Lee ◽  
Harold Horowitz ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Linkage To Care ◽  
Hospital Level ◽  
Cascade Of Care ◽  
The Individual ◽  
Individual Hospital

scholarly journals Cascade of Care for Alaska Native People With Chronic Hepatitis C Virus Infection: Statewide Program With High Linkage to Care

2019 ◽  
Vol 70 (9) ◽  
pp. 2005-2007
Author(s):  
Brian J Mcmahon ◽  
Lisa Townshend-Bulson ◽  
Chriss Homan ◽  
Prabhu Gounder ◽  
Youssef Barbour ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Alaska Native ◽  
Linkage To Care ◽  
The United States ◽  
Native People ◽  
Chronic Hepatitis C Virus ◽  
Cascade Of Care

Abstract Most persons with chronic hepatitis C virus (HCV) infection in the United States are undiagnosed or linked to care. We describe a program for the management of Alaska Native patients infection utilizing a computerized registry and statewide liver clinics resulting in higher linkage to care (86%) than national estimates (~25%).

scholarly journals Delays and gaps in progressing through the hepatitis C virus cascade of care: An underserved safety-net hospital experience

2020 ◽  
Vol 8 (4) ◽  
pp. 261-267
Author(s):  
Chantal Gomes ◽  
Dina Ginzberg ◽  
Robert J. Wong
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
African Americans ◽  
Median Time ◽  
Linkage To Care ◽  
Safety Net ◽  
Hcv Treatment ◽  
Safety Net Hospital ◽  
Cascade Of Care ◽  
Chronic Hcv

AbstractBackground and ObjectiveWhile highly effective hepatitis C virus (HCV) therapies exist, gaps in the cascade of care remain. Disparities in the HCV cascade are prominent among underserved safety-net populations. We aim to evaluate the HCV cascade among an urban safety-net cohort of HCV patients.MethodsWe retrospectively evaluated adults with chronic HCV to determine rates of linkage to care (LTC), retention to care, and receiving HCV treatment from 2002 to 2018. Comparisons between groups utilized Chi-square testing; comparisons of median time to LTC and HCV treatment were evaluated with Student’s t-test and analysis of variance.ResultsAmong 600 chronic HCV patients (60.7% male, 20.7% non-Hispanic white, 49.2% African American, 92.5% treatment naïve, 26.8% cirrhosis), successful LTC within one year of HCV diagnosis was 57.7%, among which, 91.6% were successfully retained into care. In those with successful LTC, 72.6% received HCV treatment, 91.8% completed treatment, and 89% achieved SVR12. Women with HCV experienced longer delays from LTC to HCV treatment (331 vs. 206 days in men, P < 0.05), as did African Americans (280 vs. 165 days in non-Hispanic whites, P < 0.05). Compared to the non-Hispanic whites, HCV treatment was lower in African Americans (70.4% vs. 74.4%, P < 0.05).ConclusionWomen with HCV experienced significant delays along the HCV cascade, with median time of over 2 years from diagnosis to treatment. African Americans also experienced significant delays along the HCV cascade of care. However, sex and race/ethnicity were not found to be significant predictors of overall LTC or treatment.

Pediatric Use Approved For Combination Hepatitis C Treatment

2011 ◽  
Vol 45 (9) ◽  
pp. 20
Author(s):  
Elizabeth Mechcatie
Keyword(s):  
Hepatitis C ◽  
Hepatitis C Treatment ◽  
Pediatric Use

Real-world effectiveness of Ledipasvir/Sofosbuvir 8 weeks chronic hepatitis C treatment

2015 ◽  
Vol 53 (08) ◽  
Author(s):  
P Buggisch ◽  
J Petersen ◽  
K Wursthorn ◽  
A Gauthier ◽  
P Atanasov
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Real World ◽  
Hepatitis C Treatment

The 8th Canadian Symposium on Hepatitis C virus: “Improving diagnosis and linkage to care”

2020 ◽  
Vol 3 (1) ◽  
pp. 3-14
Author(s):  
Sophie E Cousineau ◽  
Aysegul Erman ◽  
Lewis Liu ◽  
Sahar Saeed ◽  
Lorraine Fradette ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Linkage To Care
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