scholarly journals Adiposity, mediating biomarkers and risk of colon cancer in the European prospective investigation into cancer and nutrition study

2013 ◽  
Vol 134 (3) ◽  
pp. 612-621 ◽  
Author(s):  
Krasimira Aleksandrova ◽  
Dagmar Drogan ◽  
Heiner Boeing ◽  
Mazda Jenab ◽  
H. Bas Bueno-de-Mesquita ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Nutrition Study ◽  
Prospective Investigation

scholarly journals Dietary factors and in situ and invasive cervical cancer risk in the European prospective investigation into cancer and nutrition study

2010 ◽  
Vol 129 (2) ◽  
pp. 449-459 ◽  
Author(s):  
Carlos A. González ◽  
Noemie Travier ◽  
Leila Luján-Barroso ◽  
Xavier Castellsagué ◽  
F. Xavier Bosch ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Risk ◽  
Invasive Cervical Cancer ◽  
Dietary Factors ◽  
Cervical Cancer Risk ◽  
Nutrition Study ◽  
Prospective Investigation

Urinary flavanone concentrations as biomarkers of dietary flavanone intakes in the European Prospective Investigation into Cancer and Nutrition (EPIC) study

2019 ◽  
Vol 123 (6) ◽  
pp. 691-698
Author(s):  
Iasim Tahiri ◽  
Yaiza Garro-Aguilar ◽  
Valerie Cayssials ◽  
David Achaintre ◽  
Francesca Romana Mancini ◽  
...  
Keyword(s):  
Urinary Excretion ◽  
Citrus Fruit ◽  
Correlation Coefficients ◽  
European Population ◽  
Food Sources ◽  
Dietary Recall ◽  
Nutrition Study ◽  
Partial Correlations ◽  
Inaccurate Estimation ◽  
Prospective Investigation

AbstractIn the present study, the aim was to investigate the correlation between the acute and habitual dietary intake of flavanones, their main food sources and the concentrations of aglycones naringenin and hesperetin in 24 h urine in a European population. A 24-h dietary recall (24-HDR) and a 24-h urine sample were collected the same day from a subsample of 475 people from four different countries of the European Prospective Investigation into Cancer and Nutrition study. Acute and habitual dietary data were captured through a standardised 24-HDR and a country/centre-specific validated dietary questionnaire (DQ). The intake of dietary flavanones was estimated using the Phenol-Explorer database. Urinary flavanones (naringenin and hesperetin) were analysed using tandem MS with a previous enzymatic hydrolysis. Weak partial correlation coefficients were found between urinary flavanone concentrations and both acute and habitual dietary flavanone intakes (Rpartial = 0·14–0·17). Partial correlations were stronger between urinary excretions and acute intakes of citrus fruit and juices (Rpartial ∼ 0·6) than with habitual intakes of citrus fruit and juices (Rpartial ∼ 0·24). In conclusion, according to our results, urinary excretion of flavanones can be considered a good biomarker of acute citrus intake. However, low associations between habitual flavanone intake and urinary excretion suggest a possible inaccurate estimation of their intake or a too sporadic intake. For assessing habitual exposures, multiple urinary collections may be needed. These results show that none of the approaches tested is ideal, and the use of both DQ and biomarkers can be recommended.

Cigarette Smoking and Colorectal Cancer Risk in the European Prospective Investigation Into Cancer and Nutrition Study

2011 ◽  
Vol 9 (2) ◽  
pp. 137-144 ◽  
Author(s):  
Anke M. Leufkens ◽  
Fränzel J.B. Van Duijnhoven ◽  
Peter D. Siersema ◽  
Hendriek C. Boshuizen ◽  
Alina Vrieling ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Risk ◽  
Cigarette Smoking ◽  
Colorectal Cancer Risk ◽  
Nutrition Study ◽  
Prospective Investigation

scholarly journals Energy and macronutrient intake and risk of differentiated thyroid carcinoma in the European Prospective Investigation into Cancer and Nutrition study

2015 ◽  
Vol 138 (1) ◽  
pp. 65-73 ◽  
Author(s):  
Raul Zamora-Ros ◽  
Sabina Rinaldi ◽  
Konstantinos K. Tsilidis ◽  
Elisabete Weiderpass ◽  
Marie-Christine Boutron-Ruault ◽  
...  
Keyword(s):  
Thyroid Carcinoma ◽  
Differentiated Thyroid Carcinoma ◽  
Macronutrient Intake ◽  
Nutrition Study ◽  
Prospective Investigation

Dietary flavonoid, lignan and antioxidant capacity and risk of hepatocellular carcinoma in the European prospective investigation into cancer and nutrition study

2013 ◽  
Vol 133 (10) ◽  
pp. 2429-2443 ◽  
Author(s):  
Raul Zamora-Ros ◽  
Veronika Fedirko ◽  
Antonia Trichopoulou ◽  
Carlos A. González ◽  
Christina Bamia ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Antioxidant Capacity ◽  
Nutrition Study ◽  
Dietary Flavonoid ◽  
Prospective Investigation

scholarly journals Urinary Concentrations of (+)-Catechin and (-)-Epicatechin as Biomarkers of Dietary Intake of Flavan-3-Ols in the European Prospective Investigation into Cancer and Nutrition (EPIC) Study

Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 4157
Author(s):  
Enrique Almanza-Aguilera ◽  
Daniela Ceballos-Sánchez ◽  
David Achaintre ◽  
Joseph A Rothwell ◽  
Nasser Laouali ◽  
...  
Keyword(s):  
Dietary Intake ◽  
Red Wine ◽  
Food Sources ◽  
Strongly Correlated ◽  
Herbal Tea ◽  
Short Term ◽  
Dietary Recall ◽  
Nutrition Study ◽  
Habitual Intake ◽  
Prospective Investigation

This study examines the correlation of acute and habitual dietary intake of flavan-3-ol monomers, proanthocyanidins, theaflavins, and their main food sources with the urinary concentrations of (+)-catechin and (-)-epicatechin in the European Prospective Investigation into Cancer and Nutrition study (EPIC). Participants (N = 419, men and women) provided 24-h urine samples and completed a 24-h dietary recall (24-HDR) on the same day. Acute and habitual dietary data were collected using a standardized 24-HDR software and a validated dietary questionnaire, respectively. Intake of flavan-3-ols was estimated using the Phenol-Explorer database. Concentrations of (+)-catechin and (-)-epicatechin in 24-h urine were analyzed using tandem mass spectrometry after enzymatic deconjugation. Simple and partial Spearman’s correlations showed that urinary concentrations of (+)-catechin, (-)-epicatechin and their sum were more strongly correlated with acute than with habitual intake of individual and total monomers (acute rpartial = 0.13–0.54, p < 0.05; and habitual rpartial = 0.14–0.28, p < 0.01), proanthocyanidins (acute rpartial = 0.24–0.49, p < 0.001; and habitual rpartial = 0.10–0.15, p < 0.05), theaflavins (acute rpartial = 0.22–0.31, p < 0.001; and habitual rpartial = 0.20–0.26, p < 0.01), and total flavan-3-ols (acute rpartial = 0.40–0.48, p < 0.001; and habitual rpartial = 0.23–0.33, p < 0.001). Similarly, urinary concentrations of flavan-3-ols were weakly correlated with both acute (rpartial = 0.12–0.30, p < 0.05) and habitual intake (rpartial = 0.10–0.27, p < 0.05) of apple and pear, stone fruits, berries, chocolate and chocolate products, cakes and pastries, tea, herbal tea, wine, red wine, and beer and cider. Moreover, all comparable correlations were stronger for urinary (-)-epicatechin than for (+)-catechin. In conclusion, our data support the use of urinary concentrations of (+)-catechin and (-)-epicatechin, especially as short-term nutritional biomarkers of dietary catechin, epicatechin and total flavan-3-ol monomers.

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