scholarly journals Adherence to WCRF/AICR cancer prevention recommendations and metabolic syndrome in breast cancer patients

2015 ◽  
Vol 138 (1) ◽  
pp. 237-244 ◽  
Author(s):  
Eleonora Bruno ◽  
Giuliana Gargano ◽  
Anna Villarini ◽  
Adele Traina ◽  
Harriet Johansson ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Metabolic Syndrome ◽  
Cancer Prevention ◽  
Cancer Patients ◽  
Breast Cancer Patients

PP044-MON NUTRITIONAL BEHAVIOR CAN PREVENT METABOLIC SYNDROME IN BREAST CANCER PATIENTS

2012 ◽  
Vol 7 (1) ◽  
pp. 155
Author(s):  
P. Hopanci Bicakli ◽  
B. Cakar ◽  
M. Yilmaz ◽  
B. Karaca ◽  
R. Durusoy ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Metabolic Syndrome ◽  
Cancer Patients ◽  
Breast Cancer Patients ◽  
Nutritional Behavior

scholarly journals Investigation of the association between metabolic syndrome and breast cancer patients

2020 ◽  
Vol 30 (1) ◽  
pp. 187-193
Author(s):  
Delaram Eskandari ◽  
Niloofar Khodabandehloo ◽  
Abbas Gholami ◽  
Hosein Samadanifard ◽  
Alireza Hejrati
Keyword(s):  
Breast Cancer ◽  
Metabolic Syndrome ◽  
Cancer Patients ◽  
Web Of Science ◽  
Preventive Measures ◽  
Reproductive Factors ◽  
Electronic Database ◽  
Breast Cancer Patients ◽  
Total Fat ◽  
The Relationship

One of the most serious cancers among women is breast cancer. This disease is the first reason for the death of women due to cancer. Increasing breast cancer risk may associate with many factors including genetic, reproductive factors, people's lifestyle, metabolic syndrome (MS) and hormones. MS has been known as a risk factor for prostate, pancreatic, breast and colorectal cancers. The purpose of this review is to identify the relationship between MS components and breast cancer individually. This study was performed by researching electronic database references including PubMed, Google Scholar, CINAHL ProQuest, and web of science through 2019. The effect of MS with its components and breast cancer was reported in many studies.Nevertheless, a thorough understanding of the mechanisms involved remains a challenge.However, one can take several preventive measures, including a proper diet, which is one of the most important determinants of metabolic status. Also, general preventive recommendations are including reducing alcohol consumption, red meat and total fat in the diet. Moreover, increasing the consumption of vegetable and fruit reduce the proportion of MS patients to improve the outcome of breast cancer patients.

Effect of Body Mass Index on Survival in Breast Cancer Patients According to Subtype, Metabolic Syndrome, and Treatment

2018 ◽  
Vol 18 (5) ◽  
pp. e1141-e1147 ◽  
Author(s):  
Won Kyung Cho ◽  
Doo Ho Choi ◽  
Won Park ◽  
Hyejung Cha ◽  
Seok Jin Nam ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Cancer Patients ◽  
Body Mass ◽  
Breast Cancer Patients

scholarly journals Identification of Subclinical Myocardial Dysfunction in Breast Cancer Patients With Metabolic Syndrome After Cancer Related Comprehensive Therapy

2020 ◽  
Author(s):  
Feng Zhang ◽  
Siyuan Wang ◽  
Siying Liang ◽  
Chao Yu ◽  
Sufang Li ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Metabolic Syndrome ◽  
Cancer Patients ◽  
Myocardial Dysfunction ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Breast Cancer Patients ◽  
Ventricular Ejection Fraction ◽  
Comprehensive Therapy ◽  
After Cancer

Abstract Background: Breast cancer patients with metabolic syndrome have an increased risk of cardiovascular disease. These patients are more prone to suffer from cardiotoxicity after anti-cancer therapy. Patients after completion of cancer related comprehensive therapy, who show normal myocardial function, may already have subclinical myocardial dysfunction. We sought to evaluate the subclinical myocardial dysfunction in breast cancer patients with metabolic syndrome after cancer related comprehensive therapy.Methods: In this study, 45 breast cancer patients with metabolic syndrome after completion of cancer related comprehensive therapy and 45 non-breast cancer patients with metabolic syndrome were enrolled. Left ventricular ejection fraction (LVEF) and global longitudinal strain (GLS) were measured using echocardiogram. Results: All the patients have normal LVEF. However, nine breast cancer patients (20%) had GLS that was lower than -17%, while all the non-cancer patients have normal GLS. Breast cancer patients with metabolic syndrome had a decrease of GLS and LVEF, compared with non-cancer patients with metabolic syndrome. Furthermore, we found that decrease of age was associated with reduction of LVEF, and that use of trastuzumab for 1 year was a significant factor that associated with reduction of GLS.Conclusions: Breast cancer patients with metabolic syndrome after completion of cancer related comprehensive therapy suffered from subclinical myocardial dysfunction. GLS should be routinely performed to early identify subclinical myocardial damage of patients, in order to prevent the cardiotoxicity of cancer related comprehensive therapy.Trial registration: the Medical Ethics Committee of Peking University People’s Hospital, 2018PHB032-02, Registered 23 November 2018, http://www.chictr.org.cn/showproj.aspx?proj=35202

scholarly journals Weight Gain, Metabolic Syndrome, and Breast Cancer Recurrence: Are Dietary Recommendations Supported by the Data?

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Colin E. Champ ◽  
Jeff S. Volek ◽  
Joshua Siglin ◽  
Lianjin Jin ◽  
Nicole L. Simone
Keyword(s):  
Breast Cancer ◽  
Metabolic Syndrome ◽  
Weight Gain ◽  
Cancer Patients ◽  
Randomized Trials ◽  
Cancer Recurrence ◽  
Dietary Factors ◽  
Breast Cancer Recurrence ◽  
Breast Cancer Patients ◽  
Long Term Outcome

Metabolic syndrome, which can include weight gain and central obesity, elevated serum insulin and glucose, and insulin resistance, has been strongly associated with breast cancer recurrence and worse outcomes after treatment. Epidemiologic and prospective data do not show conclusive evidence as to which dietary factors may be responsible for these results. Current strategies employ low-fat diets which emphasize supplementing calories with increased intake of fruit, grain, and vegetable carbohydrate sources. Although results thus far have been inconclusive, recent randomized trials employing markedly different dietary strategies in noncancer patients may hold the key to reducing multiple risk factors in metabolic syndrome simultaneously which may prove to increase the long-term outcome of breast cancer patients and decrease recurrences. Since weight gain after breast cancer treatment confers a poor prognosis and may increase recurrence rates, large-scale randomized trials are needed to evaluate appropriate dietary interventions for our breast cancer patients.

scholarly journals The Prevalence of Metabolic Syndrome Among Newly Diagnosed Malaysian Breast Cancer Patients

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 120s-120s
Author(s):  
S.J. Kiew ◽  
T. Islam ◽  
N.A. Taib ◽  
H.A. Majid ◽  
Keyword(s):  
Breast Cancer ◽  
Metabolic Syndrome ◽  
Waist Circumference ◽  
Cancer Patients ◽  
Body Fat ◽  
Body Fat Percentage ◽  
Newly Diagnosed ◽  
Breast Cancer Patients ◽  
Fat Percentage ◽  
Increased Risk

Background: The incidence of breast cancer has increased in South East Asian (SEA) women. Malaysia has the highest obesity rates in SEA. Malaysian Breast Cancer Survivorship Cohort (MyBCC) study is a hospital-based prospective cohort study that aims to study the association between lifestyle factors and overall survival and quality of life of Malaysian breast cancer patients. Metabolic syndrome (MS) is associated with increasing levels of inflammatory cytokines and leptin that can stimulate cell proliferation through various mechanisms, hence indicating both an increased risk of developing breast cancer and a poorer prognosis. However, there is very scarce information available on the presence of MS among the newly diagnosed breast cancer patients. This is an early report of the presence of MS in the MyBCC study. Aim: We aim to evaluate the presence of MS among newly diagnosed breast cancer patients and to determine the association of MS and sociodemographic factors. Methods: 370 newly diagnosed breast cancer patients were interviewed at baseline. The anthropometric data (waist circumference, hip circumference, body weight, body height and body fat percentage) and also blood for lipid profile and glucose profile were collected. The MS status of the patients was defined using a modified International Diabetes Federation worldwide definition; presence of central obesity (waist circumference ≥ 80 cm) and any of two or more of the following criteria: (i) raised triglyceride with ≥ 1.7 mmol/L, (ii) reduced HDL-cholesterol that < 1.3 mmol/L, (iii) diagnosed with hypertension and (iv) diagnosed with diabetes. Results: Among the 370 breast cancer patients, most were aged 51 years and above (258, 69.7%), were Chinese (180, 48.6%), had secondary school education level (168, 45.4%), had less than RM3500 household income (193, 52.2%) and were postmenopausal (250, 67.6%). Most of the patients were obese or overweight (268, 72.4%) and around half of the patients (190, 51.4%) had high body fat percentage. 140 patients had MS (37.8%). MS was significantly higher among patients aged 61 years and above (59, 42.1%) and 51 to 60 years (50, 35.7%) compared with 20 to 50 years of age group (31, 22.1%) ( P < 0.05). The patients with MS were significantly higher among Chinese ethnicity (57, 40.7%), unemployed (95, 70.4%), and postmenopausal (108, 77.1%) ( P < 0.05). Conclusion: The prevalence of MS is high in newly diagnosed Malaysian breast cancer patients. With longer follow-up, further analysis will be done to look at association with outcomes.

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