Novel Polypyridyl chelators deplete cellular zinc and destabilize the X-linked inhibitor of apoptosis protein (XIAP) prior to induction of apoptosis in human prostate and breast cancer cells

Apoptosis Protein ◽

Induction Of Apoptosis ◽

Cellular Zinc

Abstract 3849: The antidiabetic drug metformin increases pro-apoptotic effect of TRAIL therapy by reducing X-linked inhibitor of apoptosis protein (XIAP) levels in triple-negative breast cancer cells

10.1158/1538-7445.am2016-3849 ◽

2016 ◽

Author(s):

Elena Strekalova ◽

Dmitry Malin ◽

Vincent Cryns

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Triple Negative Breast Cancer ◽

Breast Cancer Cells ◽

Triple Negative ◽

Inhibitor Of Apoptosis ◽

Antidiabetic Drug ◽

Apoptosis Protein ◽

Apoptotic Effect

Blockade of Rac1 Activity Induces G1 Cell Cycle Arrest or Apoptosis in Breast Cancer Cells through Downregulation of Cyclin D1, Survivin, and X-Linked Inhibitor of Apoptosis Protein

Molecular Cancer Therapeutics ◽

10.1158/1535-7163.mct-09-0906 ◽

2010 ◽

Vol 9 (6) ◽

pp. 1657-1668 ◽

Cited By ~ 54

Author(s):

Tatsushi Yoshida ◽

Yaqin Zhang ◽

Leslie A. Rivera Rosado ◽

Junjie Chen ◽

Tahira Khan ◽

...

Keyword(s):

Breast Cancer ◽

Cell Cycle ◽

Cancer Cells ◽

Breast Cancer Cells ◽

Inhibitor Of Apoptosis ◽

Cycle Arrest ◽

Rac1 Activity ◽

Apoptosis Protein ◽

G1 Cell Cycle Arrest

Abstract 3782: Benzyl isothiocyanate-induced apoptosis in human breast cancer cells is mediated by downregulation of X-linked inhibitor of apoptosis protein

10.1158/1538-7445.am10-3782 ◽

2010 ◽

Author(s):

Su-Hyeong Kim ◽

Shivendra V. Singh

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Inhibitor Of Apoptosis ◽

Human Breast Cancer Cells ◽

Human Breast ◽

Apoptosis Protein ◽

Induced Apoptosis

X-Linked Inhibitor of Apoptosis Protein Inhibits Apoptosis in Inflammatory Breast Cancer Cells with Acquired Resistance to an ErbB1/2 Tyrosine Kinase Inhibitor

Molecular Cancer Therapeutics ◽

10.1158/1535-7163.mct-10-0160 ◽

2010 ◽

Vol 9 (5) ◽

pp. 1432-1442 ◽

Cited By ~ 42

Author(s):

Katherine M. Aird ◽

Rami B. Ghanayem ◽

Sharon Peplinski ◽

Herbert K. Lyerly ◽

Gayathri R. Devi

Keyword(s):

Breast Cancer ◽

Tyrosine Kinase Inhibitor ◽

Cancer Cells ◽

Inflammatory Breast Cancer ◽

Breast Cancer Cells ◽

Kinase Inhibitor ◽

Acquired Resistance ◽

Inhibitor Of Apoptosis ◽

Abstract P1-04-01: X-Linked Inhibitor of Apoptosis Protein (XIAP) Regulates TRAIL-Induced Apoptosis in Inflammatory Breast Cancer Cells

10.1158/0008-5472.sabcs10-p1-04-01 ◽

2010 ◽

Cited By ~ 1

Author(s):

JL Allensworth ◽

KM Aird ◽

MB Murray ◽

GR. Devi

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Inflammatory Breast Cancer ◽

Breast Cancer Cells ◽

Inhibitor Of Apoptosis ◽

Apoptosis Protein ◽

Induced Apoptosis

Inhibitor of apoptosis protein‑like protein‑2: A novel growth accelerator for breast cancer cells

Oncology Reports ◽

10.3892/or.2018.6626 ◽

2018 ◽

Author(s):

Lin Zhu ◽

Weihua Zhou ◽

Xidi Zhu ◽

Siqi Xiang ◽

Siyuan Wang ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Breast Cancer Cells ◽

Inhibitor Of Apoptosis ◽

Cellular inhibitor of apoptosis protein 2 promotes the epithelial-mesenchymal transition in triple-negative breast cancer cells through activation of the AKT signaling pathway

Oncotarget ◽

10.18632/oncotarget.20227 ◽

2017 ◽

Vol 8 (45) ◽

pp. 78781-78795 ◽

Cited By ~ 5

Author(s):

Su Ji Jo ◽

Pil-Gu Park ◽

Hye-Ran Cha ◽

Sung Gwe Ahn ◽

Min Jung Kim ◽

...

Keyword(s):

Breast Cancer ◽

Breast Cancer Cells ◽

Triple Negative ◽

Epithelial Mesenchymal Transition ◽

Akt Signaling ◽

Inhibitor Of Apoptosis ◽

Akt Signaling Pathway ◽

Mesenchymal Transition ◽

The cyclin-dependent kinase inhibitor SNS-032 induces apoptosis in breast cancer cells via depletion of Mcl-1 and X-linked inhibitor of apoptosis protein and displays antitumor activity in vivo

International Journal of Oncology ◽

10.3892/ijo.2014.2467 ◽

2014 ◽

Vol 45 (2) ◽

pp. 804-812 ◽

Cited By ~ 18

Author(s):

GUI’E XIE ◽

HONGPING TANG ◽

SHAOQING WU ◽

JINGSONG CHEN ◽

JIANGWEN LIU ◽

...

Keyword(s):

Breast Cancer ◽

Antitumor Activity ◽

Breast Cancer Cells ◽

Kinase Inhibitor ◽

Inhibitor Of Apoptosis ◽

Cyclin Dependent Kinase ◽

Cyclin Dependent Kinase Inhibitor ◽

Expression of X-Linked Inhibitor of Apoptosis Protein Is a Strong Predictor of Human Prostate Cancer Recurrence

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-07-0960 ◽

2007 ◽

Vol 13 (20) ◽

pp. 6056-6063 ◽

Cited By ~ 52

Author(s):

David B. Seligson ◽

Fumiya Hongo ◽

Sara Huerta-Yepez ◽

Yoichi Mizutani ◽

Tsuneharu Miki ◽

...

Keyword(s):

Prostate Cancer ◽

Strong Predictor ◽

Cancer Recurrence ◽

Human Prostate ◽

Inhibitor Of Apoptosis ◽

Human Prostate Cancer ◽

Prostate Cancer Recurrence ◽

Simultaneous Inhibition of Cell-Cycle, Proliferation, Survival, Metastatic Pathways and Induction of Apoptosis in Breast Cancer Cells by a Phytochemical Super-Cocktail: Genes That Underpin Its Mode of Action

Journal of Cancer ◽

10.7150/jca.7235 ◽

2013 ◽

Vol 4 (9) ◽

pp. 703-715 ◽

Cited By ~ 29

Author(s):

Allal Ouhtit ◽

Rajiv Lochan Gaur ◽

Mohamed Abdraboh ◽

Shubha K. Ireland ◽

Prakash N Rao ◽

...

Keyword(s):

Breast Cancer ◽

Cell Cycle ◽

Cancer Cells ◽

Mode Of Action ◽

Breast Cancer Cells ◽

Simultaneous Inhibition ◽

Induction Of Apoptosis