scholarly journals Joint associations of parental personality traits and socio‐economic position with trajectories of offspring depression: Findings from up to 6925 families in a UK birth cohort

JCPP Advances ◽  
2021 ◽  
Author(s):  
Tim Cadman ◽  
Alex S. F. Kwong ◽  
Paul Moran ◽  
Heather O’Mahen ◽  
Iryna Culpin ◽  
...  
Keyword(s):  
Personality Traits ◽  
Birth Cohort ◽  
Economic Position ◽  
Parental Personality ◽  
Joint Associations

scholarly journals Joint associations of parental personality traits and socioeconomic position with trajectories of offspring depression: findings from up to 6925 families in a UK birth cohort.

2020 ◽  
Author(s):  
Tim Cadman ◽  
Alex Siu Fung Kwong ◽  
Paul Moran ◽  
Heather O'Mahen ◽  
Iryna Culpin ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Longitudinal Study ◽  
Personality Traits ◽  
Birth Cohort ◽  
Socioeconomic Position ◽  
Effect Modification ◽  
Absolute Increase ◽  
Parents And Children ◽  
Parental Personality ◽  
The Impact

Background: Parental personality may influence the course of offspring depression but this is unclear. It is also unknown whether the impact of parental personality on offspring depression is moderated by socioeconomic position (SEP). Our aims were to describe trajectories of depressive symptoms across adolescence for offspring of parents with and without maladaptive personality traits and to test for effect modification by SEP. Methods: A longitudinal study in the Avon Longitudinal Study of Parents and Children birth cohort (ALSPAC; ns= 3054 to 7046). Exposures were binary measures of maladaptive parental personality traits and the outcome was depressive symptoms ages 11 to 24 (SMFQ; range 0 to 26). Results: Offspring of mothers with high maladaptive traits showed higher levels of depressive symptoms at all ages (SMFQ difference at age 10 = 0.66, CI 0.25, 1.28, p = 0.02; age 22 = 1.00, CI 0.51, 1.50, p < 0.001). There was weaker evidence of an association between paternal maladaptive personality traits and offspring depressive symptoms (SMFQ difference at age 10 = 0.21, CI -0.58, - 0.99, p = 0.60; age 22 = 0.02, CI -0.94, 0.90, p= 0.97). We found no consistent evidence of effect modification by SEP. Conclusions: Offspring of mothers with high levels of maladaptive personality traits show evidence of greater depressive symptoms throughout adolescence although the absolute increase in symptoms is small. Evidence for the effect of fathers personality was weaker. Socioeconomic position and maladaptive personality traits appear to be independent risk factors.

scholarly journals Socio-economic position at four time points across the life course and all-cause mortality: updated results from the Uppsala Birth Cohort Multigenerational Study

2020 ◽  
Vol 11 (1) ◽  
pp. 27-54
Author(s):  
Amy Heshmati ◽  
Gita D Mishra ◽  
Anna Goodman ◽  
Ilona Koupil
Keyword(s):  
Life Course ◽  
Birth Cohort ◽  
Later Life ◽  
University Hospital ◽  
Sensitive Period ◽  
Saturated Model ◽  
All Cause Mortality ◽  
Economic Position ◽  
The Life Course ◽  
Multigenerational Study

Socio-economic position (SEP) is associated with all-cause mortality across all stages of the life course; however, it is valuable to distinguish at what time periods SEP has the most influence on mortality. Our aim was to investigate whether the effect of SEP on all-cause mortality accumulates over the life course or if some periods of the life course are more important. Our study population were from the Uppsala Birth Cohort Multigenerational Study, born 1915–29 at Uppsala University Hospital, Sweden. We followed 3,951 men and 3,601 women who had SEP at birth available, during childhood (at age ten), in adulthood (ages 30–45) and in later life (ages 50–65) from 15 September 1980 until emigration, death or until 31 December 2010. We compared a set of nested Cox proportional regression models, each corresponding to a specific life course model (critical, sensitive and accumulation models), to a fully saturated model, to ascertain which model best describes the relationship between SEP and mortality. Analyses were stratified by gender. For both men and women the effect of SEP across the life course on all-cause mortality is best described by the sensitive period model, whereby being advantaged in later life (ages 50–65 years) provides the largest protective effect. However, the linear accumulation model also provided a good fit of the data for women suggesting that improvements in SEP at any stage of the life course corresponds to a decrease in all-cause mortality.

scholarly journals Neuroticism, depressive symptoms and white-matter integrity in the Lothian Birth Cohort 1936

2012 ◽  
Vol 43 (6) ◽  
pp. 1197-1206 ◽  
Author(s):  
A. M. McIntosh ◽  
M. E. Bastin ◽  
M. Luciano ◽  
S. Muñoz Maniega ◽  
M. del C.Valdés Hernández ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
White Matter ◽  
Personality Traits ◽  
Birth Cohort ◽  
Disease Risk ◽  
Structural Connectivity ◽  
Temporal Cortex ◽  
White Matter Integrity ◽  
Lothian Birth Cohort ◽  
Magnetic Resonance Imaging Mri

BackgroundClinical depression is associated with reductions in white-matter integrity in several long tracts of the brain. The extent to which these findings are localized or related to depressive symptoms or personality traits linked to disease risk remains unclear.MethodMembers of the Lothian Birth Cohort 1936 (LBC936) were assessed in two waves at mean ages of 70 and 73 years. At wave 1, they underwent assessments of depressive symptoms and the personality traits of neuroticism and extraversion. Brain diffusion magnetic resonance imaging (MRI) data were obtained at the second wave and mood assessments were repeated. We tested whether depressive symptoms were related to reduced white-matter tract fractional anisotropy (FA), a measure of integrity, and then examined whether high neuroticism or low extraversion mediated this relationship.ResultsSix hundred and sixty-eight participants provided useable data. Bilateral uncinate fasciculus FA was significantly negatively associated with depressive symptoms at both waves (standardized β=0.12–0.16). Higher neuroticism and lower extraversion were also significantly associated with lower uncinate FA bilaterally (standardized β=0.09–0.15) and significantly mediated the relationship between FA and depressive symptoms.ConclusionsTrait liability to depression and depressive symptoms are associated with reduced structural connectivity in tracts connecting the prefrontal cortex with the amygdala and anterior temporal cortex. These effects suggest that frontotemporal disconnection is linked to the etiology of depression, in part through personality trait differences.

Social role and birth cohort influences on gender-linked personality traits in women: A 20-year longitudinal analysis.

2006 ◽  
Vol 91 (5) ◽  
pp. 944-958 ◽  
Author(s):  
Stephanie Kasen ◽  
Henian Chen ◽  
Joel Sneed ◽  
Thomas Crawford ◽  
Patricia Cohen
Keyword(s):  
Personality Traits ◽  
Birth Cohort ◽  
Longitudinal Analysis ◽  
Social Role
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