Inter‐individual variation in postprandial glycaemic responses in women co‐ingesting green leafy vegetables with a carbohydrate meal: interactions with the sirtuin system

AbstractThe addition of vegetable to carbohydrate-based meals has been shown to improve postprandial glucose homeostasis. Inter-individual variation in responses preclude conclusive evidence, particularly in women. The sirtuins and associated genes involved in producing the chemical, nicotinamide adenine dinucleotide (NAD), are emerging as key players in blood glucose control and may contribute to variable responses. This study aimed to investigate effects of co-ingesting green leafy vegetables (GLV) on postprandial glucose regulation following a carbohydrate meal and factors affecting inter-individual variation particularly around the sirtuin system.Twenty-five women (BMI 24.8–30.5 kg/m2) were recruited to ‘The impact of Vegetables’ (VegGI) study on acute glycaemia and Glycaemia induced CVD risk in women: metabolic effects and Inter-individual variations. Postprandial glycaemic responses (GR) following rice (75 g of available carbohydrate), rice with bok choy (150g) or spinach (150g) were measured every 5 minutes for 4 hours using a Continuous Glucose Monitoring system (Medtronic Ltd). Anthropometric, cholesterol (Cholestech LDX, Alere), HbA1c (Afinion AS100, Alere) and insulin (Mercodia AB) measures were made in a fasted state. Oestradiol, progesterone, follicular stimulating hormone and testosterone were measured (ADVIA Centaur). Total RNA was extracted from postprandial blood collected at 0 h, 30 min, 1 h and 2 h in PAXgene blood RNA tubes (PreAnalytiX GmbH) using a Blood RNA Kit (Qiagen, Crawley, UK) and quality assessed by Agilent Bioanalyser (Agilent Technologies, Bracknell, UK). Gene expression was measured using the GenomeLab System and a custom designed multiplex assay, the hSIRTNADPlex (25 targets involved in the sirtuin signalling).Linear mixed models (ver.24.0; SPSS Inc) revealed no effect of GLV consumption on postprandial GR. Principal component analysis (SIMCA-P + 12.0 software, MKS Instruments UK Ltd.) of postprandial GR indicated inter-individual variation in the responses associated with the test meals. Partial Least Square (PLS) stratified the cohort into two subgroups based on sirtuin system gene expression profiles. Postprandial GR was a contributing factor in the stratification observed, together with BMI, plasma lipid, insulin and glucose levels, but not menopausal status.Preliminary evidence indicates that co-ingesting GLV with a carbohydrate meal does not reduce postprandial GR in women (BMI 24.8–30.5 kg/m2) and that significant inter-individual variation in postprandial GR may be linked to the sirtuin system, BMI, plasma lipid, insulin, and glucose levels but not menopausal status. Recruitment and data analysis are ongoing to increase group size and further assess contributing factors.This work was supported by Scottish Government's Rural and Environment Science and Analytical Services Division

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Postprandial adropin responses in women co-ingesting green leafy vegetables with a carbohydrate meal: interactions with the sirtuin system

10.26226/morressier.5ef37080b2a27f760262bb3a ◽

2020 ◽

Author(s):

MARIETTA SAYEGH

Keyword(s):

Leafy Vegetables ◽

Green Leafy Vegetables ◽

Carbohydrate Meal

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Postprandial adropin responses in women co-ingesting green leafy vegetables with a carbohydrate meal: interactions with the sirtuin system

Proceedings of The Nutrition Society ◽

10.1017/s0029665120007302 ◽

2020 ◽

Vol 79 (OCE3) ◽

Author(s):

Marietta Sayegh ◽

Andrew Farquharson ◽

Graham Horgan ◽

Viren Ranawana ◽

Janice E. Drew

Keyword(s):

Leafy Vegetables ◽

Green Leafy Vegetables ◽

Carbohydrate Meal

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Immunity boosting diet during Covid 19

International Journal of Research in Pharmaceutical Sciences ◽

10.26452/ijrps.v11ispl1.3089 ◽

2020 ◽

Vol 11 (SPL1) ◽

pp. 832-838

Author(s):

Roshna Sukheoji Bhutada ◽

Renu Rathi ◽

Devyani Dasar

Keyword(s):

Immune System ◽

Food Studies ◽

Egg Yolk ◽

The Body ◽

Leafy Vegetables ◽

Green Leafy Vegetables ◽

Custard Apple ◽

The Right ◽

Daily Physical Activities ◽

Physiological Reactions

WHO declared Covid 19 /SARS -COV-2 as a global pandemic.Till date, there is no medicine for COVID-19. If the Infection arises in the body then the defence mechanism activated against infection. A recent study suggests that temporarily augmenting the body's immune system in the early stages of COVID-19 can help patient to avoid severe symptoms as it is rightly said prevention is better than cure. Ayurveda approaches to develop physiological reactions to facilitate immunity. Planning of diet is most important to boost immunity.As per many researches to provide supplementary food which contains Zinc, Vitamin C,Vitamin D and immunity boosting foodsuch as citrus natural products, custard apple, apple, papaya is among the Fruits. Vegetables include broccoli, onion, garlic and green leafy vegetables. Nuts, ginger, turmeric, pepper, egg yolk, shellfish, mushroom. The need of the hour is a quick boost to immune system to keep it fit, fighting. One should get the right amount of nutrients from the diet, supplementation regimen to boost immune system.In this review, there are few common supplements and super food studies have been included. It might be a torch bearer as sample menu and their alternatives are given for a normal adult. Needy may change contemplated according to age, sex, body mass index and daily physical activities.

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Do dietary patterns and morbidities have a relationship with primary infertility among women? A study from NFHS-4 (2015–16), India

Journal of Biosocial Science ◽

10.1017/s0021932021000274 ◽

2021 ◽

pp. 1-16

Author(s):

Sayeed Unisa ◽

Kanchan Negi ◽

Sucharita Pujari ◽

Vaishali Chaurasia

Keyword(s):

Dietary Patterns ◽

Family Health ◽

Severe Anaemia ◽

Married Women ◽

Leafy Vegetables ◽

Thyroid Disorder ◽

Daily Consumption ◽

High Blood Glucose ◽

Green Leafy Vegetables ◽

Primary Infertility

Abstract This study assessed the rate of primary infertility and its associated factors among 402,807 currently married women aged 20–49 years in India using National Family Health Survey-4 data collected in 2015–2016. Dietary patterns and selected morbidities were included as independent variables, and socioeconomic variables were considered as covariates. Bivariate and multivariate analyses were done to estimate the prevalence of primary infertility and assess its association with the selected variables, respectively. The rate of primary infertility among currently married women in India in 2015–16 was 1.9% and this was significantly associated with younger age (<35 years), higher age at marriage (≥18 years), urban residence, higher secondary or above education and poverty. The consumption of dairy products (OR = 0.79, CI = 0.73–0.86), dark green leafy vegetables (OR = 0.57, CI = 0.39–0.81) and fruit (OR = 0.88, CI = 0.77–1.01) significantly reduced the odds of primary infertility. Daily consumption of fish and aerated drinks was related to 1.06–1.21 times higher odds of primary infertility. Overweight/obesity, high blood pressure and high blood glucose levels were associated with 1.08–1.21 times elevated odds of primary infertility. Thyroid disorder (OR = 1.38, CI = 1.21–1.60), heart disease (OR = 1.17, CI = 1.16–1.19) and severe anaemia (OR = 1.24, CI = 1.00–1.53) were associated with an increased likelihood of primary infertility among women (OR 1.17–1.39, CI 1.00–1.60). The findings provide compelling evidence that primary infertility among women is related to dietary patterns and morbidities. Interventions and programmes targeting the promotion of healthy diets and lifestyles could be beneficial in addressing the issue of primary infertility among women.

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Biotransformation of Non-steroidal Anti-inflammatory Drugs Induces Ultrastructural Modifications in Green Leafy Vegetables

Journal of soil science and plant nutrition ◽

10.1007/s42729-021-00449-5 ◽

2021 ◽

Author(s):

Ocsana Opriș ◽

Maria-Loredana Soran ◽

Ildikó Lung ◽

Alexandra Ciorîță ◽

Lucian Copolovici

Keyword(s):

Leafy Vegetables ◽

Green Leafy Vegetables ◽

Inflammatory Drugs ◽

Ultrastructural Modifications ◽

Anti Inflammatory

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Determinants and Suitability of Carotenoid Reflection Score as a Measure of Carotenoid Status

Nutrients ◽

10.3390/nu12010113 ◽

2020 ◽

Vol 12 (1) ◽

pp. 113 ◽

Cited By ~ 1

Author(s):

Elaine Rush ◽

Isaac Amoah ◽

Tung Diep ◽

Shabnam Jalili-Moghaddam

Keyword(s):

Body Size ◽

Health Outcomes ◽

Daily Intake ◽

Leafy Vegetables ◽

Carotenoid Concentration ◽

Dairy Foods ◽

Green Leafy Vegetables ◽

Positive Correlations ◽

Dark Green ◽

Negative Health Outcomes

Carotenoids, orange-coloured pigments found in vegetables, fruit, eggs and dairy foods, act as antioxidants and vitamin A precursors in the human body. Skin carotenoid concentration is a biomarker of vegetable and fruit intake. The aim was to identify determinants of skin carotenoid concentration by measuring “Veggie Meter™” carotenoid reflection spectroscopy scores (CRS) from the fingertip of adults with a range of ages, ethnicity and body size. Frequencies of daily intake of vegetables and fruit and weekly intake of pumpkin and carrot, dark green leafy vegetables (DGLV), eggs (yolk), and dairy were determined from a self-completed food-frequency-questionnaire. A total of 571 (324 Women, 247 Men) adults, aged 16 to 85 years, completed measurements. The CRS ranged from 83 to 769, with a median of 327. Women and men did not score differently. For all participants there were negative correlations of CRS with weight (r = −0.312) and BMI (r = −0.338) and positive correlations with weekly intakes of DGLV (r = 0.242) and carrots and pumpkin (r = 0.202). Based on a review of health outcomes associated with plasma carotenoids, 82% of the participants in the current study are at moderate risk, or more, of negative health outcomes. Determinants of carotenoid status were body size, intake of DGLV, carrots and pumpkin, and ethnicity.

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