Curcumin suppresses cell proliferation and triggers apoptosis in vemurafenib‐resistant melanoma cells by downregulating the EGFR signaling pathway

2022 ◽  
Author(s):  
Yu‐Jen Chiu ◽  
Jai‐Sing Yang ◽  
Fuu‐Jen Tsai ◽  
Hong‐Yi Chiu ◽  
Yu‐Ning Juan ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Signaling Pathway ◽  
Melanoma Cells ◽  
Egfr Signaling ◽  
Egfr Signaling Pathway

Tu1606 Galectin-3 Regulates Gastric Cancer Cell Proliferation Through EGFR Signaling Pathway.

2013 ◽  
Vol 144 (5) ◽  
pp. S-804
Author(s):  
Nobuko Serizawa ◽  
Akihito Nagahara ◽  
Shunhei Yamashina ◽  
Gentaro Taniguchi ◽  
Sumio Watanabe
Keyword(s):  
Gastric Cancer ◽  
Cell Proliferation ◽  
Signaling Pathway ◽  
Cancer Cell ◽  
Gastric Cancer Cell ◽  
Cancer Cell Proliferation ◽  
Egfr Signaling ◽  
Egfr Signaling Pathway ◽  
Galectin 3 ◽  
Gastric Cancer Cell Proliferation

Kaempferol inhibits cell proliferation and glycolysis in esophagus squamous cell carcinoma via targeting EGFR signaling pathway

Tumor Biology ◽  
2016 ◽  
Vol 37 (8) ◽  
pp. 10247-10256 ◽  
Author(s):  
Shihua Yao ◽  
Xiaowei Wang ◽  
Chunguang Li ◽  
Tiejun Zhao ◽  
Hai Jin ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Signaling Pathway ◽  
Squamous Cell ◽  
Egfr Signaling ◽  
Egfr Signaling Pathway ◽  
Esophagus Squamous Cell Carcinoma

scholarly journals Effect of Cyclophilin from Pyropia Yezoensis on the Proliferation of Intestinal Epithelial Cells by Epidermal Growth Factor Receptor/Ras Signaling Pathway

Marine Drugs ◽  
2019 ◽  
Vol 17 (5) ◽  
pp. 297 ◽  
Author(s):  
Jae-Hun Jung ◽  
Jeong-Wook Choi ◽  
Min-Kyeong Lee ◽  
Youn-Hee Choi ◽  
Taek-Jeong Nam
Keyword(s):  
Cell Cycle ◽  
Cell Proliferation ◽  
Epithelial Cells ◽  
Signaling Pathway ◽  
Intestinal Epithelial Cells ◽  
Ras Signaling ◽  
Intestinal Epithelial ◽  
Egfr Signaling ◽  
Egfr Signaling Pathway ◽  
Ras Signaling Pathway

Cyclophilin (Cyp) is peptidyl–prolyl isomerase (PPIase), and it has many biological functions, including immune response regulation, antioxidants, etc. Cyp from red algae is known for its antioxidant and antifungal activity. However, the other biological effects of Cyp from Pyropia yezoensis are unclear. In this study, we synthesized Cyp from P. yezoensis (pyCyp) and examined its biological activity on IEC-6 cells. First, the MTS assay showed that pyCyp increased cell proliferation in a dose-dependent manner. pyCyp activated the EGFR signaling pathway that regulates cell growth, proliferation, and survival. It induced intracellular signaling pathways, including the Ras signaling pathway. In addition, we observed cell cycle-related proteins. pyCyp increased the expression of cyclin A, cyclin E, and Cdk2, and decreased the expression of p27 and p21 proteins. These results indicate that pyCyp stimulates cell proliferation via the EGFR signaling pathway and promotes cell cycle progression in intestinal epithelial cells. Therefore, we suggest pyCyp as a potential material to promote the proliferation of intestinal epithelial cells.

scholarly journals β1, 4-N-acetylgalactosaminyltransferase III modulates cancer stemness through EGFR signaling pathway in colon cancer cells

Oncotarget ◽  
2014 ◽  
Vol 5 (11) ◽  
pp. 3673-3684 ◽  
Author(s):  
Mei-Ieng Che ◽  
John Huang ◽  
Ji-Shiang Hung ◽  
Yo-Chuen Lin ◽  
Miao-Juei Huang ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Cancer Cells ◽  
Signaling Pathway ◽  
Colon Cancer Cells ◽  
Egfr Signaling ◽  
Cancer Stemness ◽  
Egfr Signaling Pathway

scholarly journals miR-19b enhances proliferation and apoptosis resistance via the EGFR signaling pathway by targeting PP2A and BIM in non-small cell lung cancer

2018 ◽  
Vol 17 (1) ◽  
Author(s):  
Ulrich Baumgartner ◽  
Fabienne Berger ◽  
Ali Hashemi Gheinani ◽  
Sabrina Sofia Burgener ◽  
Katia Monastyrskaya ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Signaling Pathway ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Egfr Signaling ◽  
Small Cell Lung ◽  
Apoptosis Resistance ◽  
Egfr Signaling Pathway ◽  
Proliferation And Apoptosis

scholarly journals miR-20b reduces 5-FU resistance by suppressing the ADAM9/EGFR signaling pathway in colon cancer

2016 ◽  
Vol 37 (1) ◽  
pp. 123-130 ◽  
Author(s):  
Qiang Fu ◽  
Jing Cheng ◽  
Jindai Zhang ◽  
Yonglei Zhang ◽  
Xiaobing Chen ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Signaling Pathway ◽  
Egfr Signaling ◽  
Egfr Signaling Pathway
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