Mesoscopic Structures as an Intermediate Stage between Molecules (Micro Scale) on the One Hand and Biological Cells (Macro Scale) on the other

2021 ◽  
pp. 25-49
Author(s):  
Robert W. Batterman

This chapter relates the philosophical concept of multiple realizability to the physics concept of universality. It discusses and responds to Elliott Sober’s defense of reductionism in the face of multiple realizability. Further, it introduces an important explanatory question (labelled AUT). This asks how systems that are heterogeneous at some micro-scale can exhibit the same pattern of behavior at the macro-scale. It is shown that reductionists do not have the resources to provide a successful answer. Two, related, answers are proposed. One involving Renormalization Group arguments, the other invoking the theory of homogenization.


Probus ◽  
2013 ◽  
Vol 25 (2) ◽  
pp. 227-265 ◽  
Author(s):  
Víctor Acedo-Matellán ◽  
Jaume Mateu

Abstract In this paper we are interested in the relation between two facts accompanying the diachronic change from Latin to Romance within the domain of the morphological and argument-structural properties of the predicates expressing change. On the one hand, the element encoding the transition itself, which we call the Path, and the verb are realised as two distinct morphemes in Latin, but as one and the same morpheme in the daughter languages: in Talmy's (2000) terms, the former is a satellite-framed language and the latter are verb-framed languages. On the other hand, there is a whole range of argument-structural patterns which are found in Latin but not in Romance: unselected object contructions, complex directed motion constructions, productive locative alternation, etc. We show, within a syntactic view of argument structure and morphology, that both facts are intimately related. Furthermore, we provide data from Old Catalan showing an intermediate stage between the Latin satellite-framed system and the Romance verb-framed system.


2020 ◽  
Vol Lietuvos archeologija T. 46 ◽  
pp. 171-189
Author(s):  
Sławomir Kadrow

The aim of the article is to outline the causes, mechanisms, and course of the Neolithisation process in South-Eastern Poland, as seen from a global (macro-) and local (microregional) perspective. It has been assumed that the most effective tool for analyzing this process on a macro scale is a set of concepts and rules constituting the theory of globalization (Hodos 2017). Cultural analysis (Wuthnow 1987), on the other hand, considers conflict as the main driving force of deep changes on a micro scale. Globalization is a form of connectivity that is the price humans pay to access resources that satisfy their desire for status and wellbeing. A common human pursuit is the desire to achieve a higher status and to improve one’s own wellbeing. People, realizing their intentions and aspirations, enter into conflicts which can potentially be one of the main sources of crises, and thus also of cultural change. Keywords: Neolithisation, SE Poland, Linear Band Pottery culture, globalization, cultural analysis, conflict.


Author(s):  
Caroline Bassett

This chapter considers Perec’s interest in the infra-ordinary, on the one hand, and questions of the machine and automation, on the other. Investigating different ways in which the micro-scale emerges in Perec’s work raises questions around life in relation to (computational) machines – particularly machines that are getting smaller (at once more discreet, and less discrete) – that are becoming ever more important today. This chapter examines the complex relationship between questions of life (the infra-ordinary life with its embedded habits) and questions concerning classification – here understood as a form of automation, as they are raised (and develop very differently) in Perec’s work on the self, the space, the object, and the language game.


1975 ◽  
Vol 26 ◽  
pp. 395-407
Author(s):  
S. Henriksen

The first question to be answered, in seeking coordinate systems for geodynamics, is: what is geodynamics? The answer is, of course, that geodynamics is that part of geophysics which is concerned with movements of the Earth, as opposed to geostatics which is the physics of the stationary Earth. But as far as we know, there is no stationary Earth – epur sic monere. So geodynamics is actually coextensive with geophysics, and coordinate systems suitable for the one should be suitable for the other. At the present time, there are not many coordinate systems, if any, that can be identified with a static Earth. Certainly the only coordinate of aeronomic (atmospheric) interest is the height, and this is usually either as geodynamic height or as pressure. In oceanology, the most important coordinate is depth, and this, like heights in the atmosphere, is expressed as metric depth from mean sea level, as geodynamic depth, or as pressure. Only for the earth do we find “static” systems in use, ana even here there is real question as to whether the systems are dynamic or static. So it would seem that our answer to the question, of what kind, of coordinate systems are we seeking, must be that we are looking for the same systems as are used in geophysics, and these systems are dynamic in nature already – that is, their definition involvestime.


Author(s):  
Stefan Krause ◽  
Markus Appel

Abstract. Two experiments examined the influence of stories on recipients’ self-perceptions. Extending prior theory and research, our focus was on assimilation effects (i.e., changes in self-perception in line with a protagonist’s traits) as well as on contrast effects (i.e., changes in self-perception in contrast to a protagonist’s traits). In Experiment 1 ( N = 113), implicit and explicit conscientiousness were assessed after participants read a story about either a diligent or a negligent student. Moderation analyses showed that highly transported participants and participants with lower counterarguing scores assimilate the depicted traits of a story protagonist, as indicated by explicit, self-reported conscientiousness ratings. Participants, who were more critical toward a story (i.e., higher counterarguing) and with a lower degree of transportation, showed contrast effects. In Experiment 2 ( N = 103), we manipulated transportation and counterarguing, but we could not identify an effect on participants’ self-ascribed level of conscientiousness. A mini meta-analysis across both experiments revealed significant positive overall associations between transportation and counterarguing on the one hand and story-consistent self-reported conscientiousness on the other hand.


2005 ◽  
Vol 44 (03) ◽  
pp. 107-117
Author(s):  
R. G. Meyer ◽  
W. Herr ◽  
A. Helisch ◽  
P. Bartenstein ◽  
I. Buchmann

SummaryThe prognosis of patients with acute myeloid leukaemia (AML) has improved considerably by introduction of aggressive consolidation chemotherapy and haematopoietic stem cell transplantation (SCT). Nevertheless, only 20-30% of patients with AML achieve long-term diseasefree survival after SCT. The most common cause of treatment failure is relapse. Additionally, mortality rates are significantly increased by therapy-related causes such as toxicity of chemotherapy and complications of SCT. Including radioimmunotherapies in the treatment of AML and myelodyplastic syndrome (MDS) allows for the achievement of a pronounced antileukaemic effect for the reduction of relapse rates on the one hand. On the other hand, no increase of acute toxicity and later complications should be induced. These effects are important for the primary reduction of tumour cells as well as for the myeloablative conditioning before SCT.This paper provides a systematic and critical review of the currently used radionuclides and immunoconjugates for the treatment of AML and MDS and summarizes the literature on primary tumour cell reductive radioimmunotherapies on the one hand and conditioning radioimmunotherapies before SCT on the other hand.


2017 ◽  
Vol 47 (188) ◽  
pp. 487-494
Author(s):  
Daniel Mullis

In recent years, political and social conditions have changed dramatically. Many analyses help to capture these dynamics. However, they produce political pessimism: on the one hand there is the image of regression and on the other, a direct link is made between socio-economic decline and the rise of the far-right. To counter these aspects, this article argues that current political events are to be understood less as ‘regression’ but rather as a moment of movement and the return of deep political struggles. Referring to Jacques Ranciere’s political thought, the current conditions can be captured as the ‘end of post-democracy’. This approach changes the perspective on current social dynamics in a productive way. It allows for an emphasis on movement and the recognition of the windows of opportunity for emancipatory struggles.


1996 ◽  
pp. 13-23
Author(s):  
Mykhailo Babiy

Political ideological pluralism, religious diversity are characteristic features of modern Ukrainian society. On the one hand, multiculturalism, socio-political, religious differentiation of the latter appear as important characteristics of its democracy, as a practical expression of freedom, on the other - as a factor that led to the deconsocialization of society, gave rise to "nodal points" of tension, confrontational processes, in particular, in political and religious spheres.


2003 ◽  
pp. 15-26
Author(s):  
P. Wynarczyk
Keyword(s):  
The Core ◽  

Two aspects of Schumpeter' legacy are analyzed in the article. On the one hand, he can be viewed as the custodian of the neoclassical harvest supplementing to its stock of inherited knowledge. On the other hand, the innovative character of his works is emphasized that allows to consider him a proponent of hetherodoxy. It is stressed that Schumpeter's revolutionary challenge can lead to radical changes in modern economics.


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