The Influence of L-NAME on iNOS Expression and Markers of Oxidative Stress in Allergen-Induced Airway Hyperreactivity

2014 ◽  
pp. 1-10 ◽  
Author(s):  
M. Antošová ◽  
A. Strapková ◽  
P. Mikolka ◽  
J. Mokrý ◽  
I. Medveďová ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Inos Expression ◽  
Airway Hyperreactivity ◽  
Markers Of Oxidative Stress

scholarly journals Oxidative status in plasma, urine and saliva of girls with anorexia nervosa and healthy controls: a cross-sectional study

2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Alexandra Gaál Kovalčíková ◽  
Ľubica Tichá ◽  
Katarína Šebeková ◽  
Peter Celec ◽  
Alžbeta Čagalová ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Anorexia Nervosa ◽  
Redox Homeostasis ◽  
Oxidative Status ◽  
Carbonyl Stress ◽  
Healthy Controls ◽  
Psychosomatic Disorder ◽  
Cross Sectional ◽  
Wide Range ◽  
Markers Of Oxidative Stress

Abstract Background Anorexia nervosa (AN) is a serious psychosomatic disorder with unclear pathomechanisms. Metabolic dysregulation is associated with disruption of redox homeostasis that might play a pivotal role in the development of AN. The aim of our study was to assess oxidative status and carbonyl stress in plasma, urine and saliva of patients with AN and healthy controls. Methods Plasma, spot urine, and saliva were collected from 111 girls with AN (aged from 10 to 18 years) and from 29 age-matched controls. Markers of oxidative stress and antioxidant status were measured using spectrophotometric and fluorometric methods. Results Plasma advanced oxidation protein products (AOPP) and advanced glycation end products (AGEs) were significantly higher in patients with AN than in healthy controls (by 96, and 82%, respectively). Accordingly, urinary concentrations of AOPP and fructosamines and salivary concentrations of AGEs were higher in girls with AN compared with controls (by 250, and 41% in urine; by 92% in saliva, respectively). Concentrations of thiobarbituric acid reactive substances (TBARS) in saliva were 3-times higher in the patients with AN than in the controls. Overall antioxidants were lower in plasma of girls with AN compared to the controls, as shown by total antioxidant capacity and ratio of reduced and oxidized glutathione (by 43, and 31%, respectively). Conclusions This is the first study assessing wide range of markers of oxidative status in plasma, urine and saliva of the patients with AN. We showed that both, higher levels of markers of oxidative stress and lower antioxidants play a role in redox disruption. Restoration of redox homeostasis might be of the clinical relevance

scholarly journals Effect of Tai Chi on Markers of Oxidative Stress: Systematic Review and Meta-Analysis

2021 ◽  
Vol 18 (7) ◽  
pp. 3458
Author(s):  
Juana Rosado-Pérez ◽  
Osvaldo D. Castelán-Martínez ◽  
Abril J. Mújica-Calderón ◽  
Martha A. Sánchez-Rodríguez ◽  
Víctor Manuel Mendoza-Núñez
Keyword(s):  
Oxidative Stress ◽  
Systematic Review ◽  
Superoxide Dismutase ◽  
Sedentary Behavior ◽  
Tai Chi ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Stress Markers ◽  
Markers Of Oxidative Stress ◽  
Mean Differences

Background: This study aimed to synthesize the evidence of the effect of practicing Tai Chi on oxidative stress markers (OxSM). Methods: This systematic review and meta-analysis was conducting using the MEDLINE, Cochrane Library, ScienceDirect, Scopus, Epistemonikos, Lilacs, and Ovid databases to identify randomized (RCT) and non-randomized (NRCT) clinical trials that evaluated the Tai Chi effect on OxSM compared to sedentary behavior, walking or yoga. Pooled mean differences (MDs) with 95% confidence intervals (95%CI) were estimated using the inverse variance method to determine the effect of Tai Chi on OxSM. PROSPERO register: CRD42019138362. Results: Five RCT and five NRCT were included. Compared to sedentary behavior, regular Tai Chi practice increases the levels of the enzymes superoxide dismutase (MD = 34.97 U/mL, (95%CI, 9.45 to 60.48), 344 participants) and catalase (MD = 15.63 U/mL, (95%CI, 4.05 to 27.22), 110 participants), as well as reducing the levels of lipoperoxides (MD = −0.02 µmol/L, (95%CI, −0.04 to −0.00), 234 participants). For comparisons with walking or yoga, only one study per activity was identified comparing the effect on OxSM. Conclusions: Regular Tai Chi practice increases the levels of superoxide dismutase and catalase, as well as reducing the levels of lipoperoxides. More studies are necessary to determine the effect of Tai Chi on OxSM when compared to other physical activities.

scholarly journals Effect of antioxidant supplementation on urine and blood markers of oxidative stress during extended moderate-altitude training

1999 ◽  
Vol 10 (2) ◽  
pp. 66-74 ◽  
Author(s):  
Jeffrey M. Pfeiffer ◽  
Eldon W. Askew ◽  
Donald E. Roberts ◽  
Steven M. Wood ◽  
Joan E. Benson ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Altitude Training ◽  
Moderate Altitude ◽  
Antioxidant Supplementation ◽  
Markers Of Oxidative Stress

scholarly journals Transdermal nitroglycerin therapy is not associated with biochemical markers of oxidative stress

1998 ◽  
Vol 31 ◽  
pp. 395
Author(s):  
S.D. Milone ◽  
C.R. Pace-Asciak ◽  
E.R. Azevedo ◽  
G.E. Newton ◽  
J.D. Parker
Keyword(s):  
Oxidative Stress ◽  
Biochemical Markers ◽  
Markers Of Oxidative Stress

scholarly journals Markers of oxidative stress in uremia

2004 ◽  
Vol 65 (1) ◽  
pp. 340
Author(s):  
Véronique Witko-Sarsat ◽  
Chantal Capeillere-Blandin ◽  
Béatrice Descamps-Latscha
Keyword(s):  
Oxidative Stress ◽  
Markers Of Oxidative Stress

Erythrocyte Markers of Oxidative Stress in Higher Age-Group Preeclamptic and Normal Pregnant Mothers

2010 ◽  
Vol 29 (1) ◽  
pp. 69-81 ◽  
Author(s):  
Syed K. Haque ◽  
Mashiat U. Siddiqui ◽  
Najmul Islam ◽  
Shagufta Moin
Keyword(s):  
Oxidative Stress ◽  
Age Group ◽  
Markers Of Oxidative Stress ◽  
Pregnant Mothers

Differential susceptibility of a few members of the nasuta–albomicans complex of Drosophila to paraquat-induced lethality and oxidative stress

Genome ◽  
2011 ◽  
Vol 54 (10) ◽  
pp. 829-835 ◽  
Author(s):  
Mysore S. Ranjini ◽  
Ravikumar Hosamani ◽  
Muralidhara ◽  
Nallur B. Ramachandra
Keyword(s):  
Oxidative Stress ◽  
Biochemical Analysis ◽  
Reduced Glutathione ◽  
Differential Susceptibility ◽  
Activity Levels ◽  
Oxygen Species ◽  
Stress Markers ◽  
The Status ◽  
Markers Of Oxidative Stress ◽  
And Oxidative Stress

The evolution of karyotypically stabilized short-lived (SL) and long-lived (LL) cytoraces in the laboratory have been established and validated through our previous lifespan studies. In the present investigation, we examined the possible reason(s) for the differential longevity among selected members of SL and LL cytoraces, employing the well known paraquat (PQ) resistance bioassay. Exposure of these races to varying concentrations of PQ revealed relatively higher resistance among LL cytoraces than SL cytoraces, as evident by the lower incidence of mortality. Biochemical analysis for endogenous markers of oxidative stress revealed that LL-2 cytorace exhibited lower reactive oxygen species (ROS) and lipid peroxidation (LPO) levels, higher activity levels of superoxide dismutase (SOD), and coupled with higher levels of reduced glutathione (GSH) compared with the levels found in SL-2 cytorace. These findings suggest that the higher susceptibility of SL cytoraces to PQ challenge may be, at least in part, related to the higher endogenous levels of oxidative stress markers. Although the precise mechanisms responsible for the longer longevity among LL cytoraces of the nasuta–albomicans complex of Drosophila merits further investigation, our data suggest that the relatively longer lifespan may be related to the status of endogenous markers that renders them more resistant towards oxidative-stress-mediated lethality, as evident in the PQ assay.

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