The Relationship of Weight-Bearing Physical Activity and Dietary Calcium Intake with Bone Mass Accrual in the Bone Mineral Density in Childhood Study Cohort

Author(s):  
Joan Lappe ◽  
Patrice Watson ◽  
Vicente Gilsanz ◽  
Heidi J. Kalkwarf ◽  
Thomas N. Hangartner ◽  
...  
2000 ◽  
Vol 12 (2) ◽  
pp. 198-216 ◽  
Author(s):  
Han C.G. Kemper

This paper reviews the growth and development of skeletal mass in youth and the effects of physical activity upon the bone mass in young people. The different methods to measure the bone mass are described such as anthropometrics, radiographics, dual energy X-ray absorptiometry, quantitative computed tomography, and ultrasound. Two different mechanisms are important for the formation and plasticity of bone: a central hormonal mechanism (with estrogen production) and a local mechanism (based on mechanical forces of gravity and muscle contractions). This local mechanism is closely connected to physical activity patterns and therefore discussed in more detail. Thereafter the natural course of the development of the bone mass during youth is described, taking into account the pubertal stages of boys and girls and also the age at which the maximal bone mass (peak bone mineral density) will be reached. The last part is devoted to the effects of physical activity on bone mass based on results of randomized controlled trials. Although the number of experimental studies are scarce, significant effects of weight bearing activity and high impact strength training programs are shown on the side specific bone mineral density in both boys and girls.


2006 ◽  
Vol 18 (1) ◽  
pp. 101-112 ◽  
Author(s):  
Kristin S. Ondrak ◽  
Don W. Morgan

The influence of height, body mass, daily physical activity (DPA), and dietary calcium intake (DCI) on bone mineral density (BMD) and content (BMC) was evaluated in 33 four-year-old girls. Results indicated that body mass was significantly correlated with and predictive of BMD and BMC at all sites except the femoral neck BMD. DPA and height also explained a significant proportion of the variance in femoral neck BMD and BMC of the lumbar spine and total body. DCI was not related to or predictive of BMD or BMC at any bone site. These findings highlight the importance of engaging in daily weight-bearing physical activity to promote bone health in young girls.


2020 ◽  
Vol 26 (2) ◽  
pp. 70-74
Author(s):  
Mehmet Göktuğ Kılınçarslan ◽  
Erkan Melih Şahin ◽  
Banu Sarıgül ◽  
Sinem Bilgen Kocaoğlu

2012 ◽  
Vol 25 (3) ◽  
pp. 331-340 ◽  
Author(s):  
Susan Ziglar ◽  
Tracy S. Hunter

Maximizing bone mass in youth is touted as the best strategy to offset the natural losses of aging and the menopausal transition. Not achieving maximum peak bone mineral density (BMD) is an independent risk factor for osteoporosis and thus a public health concern. Adolescence is a critical time of bone mineralization mediated by endogenous estradiol. Research has shown that the highest velocity of bone mass accrual occurs 1 year before menarche and after the first 3 years. Low-peak attainment of BMD in young women is associated with contributing factors such as diets low in calcium, eating disorders, lack of exercise, smoking, and low estrogen states. Oral contraceptives (OCs) suppress endogenous estradiol production by suppressing the hypothalamic–pituitary–ovarian axis. Thus, OCs, by replacing endogenous estradiol with ethinyl estradiol (EE), establish and maintain new hormone levels. The early initiation and the use of very low dose of EE raises the possibility that bone mass accrual at a critical time of bone mineralization in young women or adolescents may be jeopardized. This review examines the studies of BMD in adolescents and young women that use combination hormonal contraception. Some studies had inherent limitations, such as small trial, poor control of confounders, failure to exclude women with prior use of hormonal contraceptives, or prior pregnancy from control groups. The vast majority of reviewed studies showed OCs containing 20 to 30 µg of EE interfere with acquisition of peak BMD. Limited numbers of studies examine the effects of OCs containing 35 µg on adolescents and young adults. Additionally, studies are needed evaluating the progestin component of OCs as their differing androgenic properties may affect bone mineralization as well.


2018 ◽  
Vol 104 (3) ◽  
pp. 892-899 ◽  
Author(s):  
Joseph M Kindler ◽  
Andrea J Lobene ◽  
Kara A Vogel ◽  
Berdine R Martin ◽  
Linda D McCabe ◽  
...  

Abstract Context Insulin resistance is an adverse health outcome that accompanies obesity. Fat mass is negatively associated with the bone mass after adjustment for confounders. Insulin resistance might be an intermediary in this relationship. Objective To determine whether insulin resistance is an intermediary in the relationship between adiposity and bone mass in adolescents. Design Cross-sectional secondary analysis of baseline data from a previous randomized trial. Setting University research facility. Participants A total of 240 adolescents (68% female), aged 7 to 15 years. Main Outcome Measures Using dual energy x-ray absorptiometry, bone mineral content (BMC), areal bone mineral density, lean mass, and fat mass were measured. Skeletal sites of interest included the total body and lumbar spine (LS). Waist circumference was measured using an anthropometric tape measure. Insulin and glucose were measured in fasting sera, and the homeostasis model assessment of insulin resistance (HOMA-IR) was calculated. Path analysis was performed to determine whether the relationship between adiposity and bone was mediated through insulin resistance. Results Fat mass (r = 0.467; P < 0.001) and waist circumference (r = 0.487; P < 0.001) correlated positively with HOMA-IR. Controlling for race, sex, maturation, lean mass, and height, fat mass, waist circumference, and HOMA-IR were negatively associated with LS BMC and total body areal bone mineral density (P < 0.05 for all). Additionally, path models for fat mass (95% CI, −5.893 to −0.956) and waist circumference (95% CI, −15.473 to −2.124) showed a negative relationship with LS BMC via HOMA-IR. Conclusions These results support an intermediary role of insulin resistance in the relationship between adiposity and LS bone mass.


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