Bioavailability of Prednisolone in Rabbits: Comparison of a High-Viscosity Gel and An Aqueous Suspension—Single- and Repeated Applications

Author(s):  
Sven Johansen ◽  
Eva Rask-Pedersen ◽  
Jan Ulrik Prause

2018 ◽  
Vol 931 ◽  
pp. 481-488
Author(s):  
Svetlana V. Samchenko ◽  
Irina V. Kozlova ◽  
Olga V. Zemskova

The entry presents studies of the effect of dispersion temperature on the deposition rate of CNTs in the presence of a plasticizer based on sulfonated naphthalene formaldehyde resins, on the dispersed composition of CNTs in aqueous and aqueous-polymer dispersion media and on the strength characteristics of samples with stabilized CNTs. It was established that the ultrasonic dispersion of aqueous suspensions of CNTs in the presence of a plasticizer based on sulfonated naphthalene formaldehyde resins at an ultrasonic vibration frequency of 44 kHz; dispersion temperature - 25 ± 2 °C; dispersion time - 10 - 30 minutes is capable of ensuring the stability of CNTs suspensions for 7 days or more. The mechanism of stabilization of aqueous suspension of CNTs by a plasticizer based on sulfonated naphthalene formaldehyde resins is presented. It has been established that the stabilization of CNTs is achieved by fixing the functional groups of the plasticizer on the surface of the nanoparticle, the nonpolar component of which ensures the formation of a high-viscosity interlayer between the CNTs particles and the dispersion medium, and the polar component is the formation of a double electric layer (DEL) that promotes the micellization of CNTs. As a result, the CNTs stabilized with sulfonaphthalene formaldehyde are evenly distributed in the volume of the cement system, causing the production of cement stone with enhanced performance properties.



1992 ◽  
Vol 11 (1) ◽  
pp. 43-49 ◽  

Isopropyl Isostearate, the ester of isopropyl alcohol and isostearic acid, is used as a skin conditioning agent-emollient in cosmetic products. Undiluted Isopropyl Isostearate was classified as a slight ocular irritant. Repeated applications of a 10.0% aqueous suspension of Isopropyl Isostearate to the skin of albino rabbits was well-tolerated. Based upon the safety test data on chemically similar isopropyl esters that is summarized in the report, it is concluded that Isopropyl Isostearate is safe as a cosmetic ingredient in the present practices of use and concentration.



Author(s):  
H. Mori ◽  
Y. Murata ◽  
H. Yoneyama ◽  
H. Fujita

Recently, a new sort of nano-composites has been prepared by incorporating such fine particles as metal oxide microcrystallites and organic polymers into the interlayer space of montmorillonite. Owing to their extremely large specific surface area, the nano-composites are finding wide application[1∼3]. However, the topographic features of the microstructures have not been elucidated as yet In the present work, the microstructures of iron oxide-pillared montmorillonite have been investigated by high-resolution transmission electron microscopy.Iron oxide-pillared montmorillonite was prepared through the procedure essentially the same as that reported by Yamanaka et al. Firstly, 0.125 M aqueous solution of trinuclear acetato-hydroxo iron(III) nitrate, [Fe3(OCOCH3)7 OH.2H2O]NO3, was prepared and then the solution was mixed with an aqueous suspension of 1 wt% clay by continuously stirring at 308 K. The final volume ratio of the latter aqueous solution to the former was 0.4. The clay used was sodium montmorillonite (Kunimine Industrial Co.), having a cation exchange capacity of 100 mequiv/100g. The montmorillonite in the mixed suspension was then centrifuged, followed by washing with deionized water. The washed samples were spread on glass plates, air dried, and then annealed at 673 K for 72 ks in air. The resultant film products were approximately 20 μm in thickness and brown in color.



2009 ◽  
Vol 106 (6) ◽  
pp. 242-247
Author(s):  
C. Damerval ◽  
H. Tavernier ◽  
L. Avedian ◽  
P. Disant ◽  
P. Delfosse ◽  
...  


TAPPI Journal ◽  
2018 ◽  
Vol 17 (09) ◽  
pp. 507-515 ◽  
Author(s):  
David Skuse ◽  
Mark Windebank ◽  
Tafadzwa Motsi ◽  
Guillaume Tellier

When pulp and minerals are co-processed in aqueous suspension, the mineral acts as a grinding aid, facilitating the cost-effective production of fibrils. Furthermore, this processing allows the utilization of robust industrial milling equipment. There are 40000 dry metric tons of mineral/microfbrillated (MFC) cellulose composite production capacity in operation across three continents. These mineral/MFC products have been cleared by the FDA for use as a dry and wet strength agent in coated and uncoated food contact paper and paperboard applications. We have previously reported that use of these mineral/MFC composite materials in fiber-based applications allows generally improved wet and dry mechanical properties with concomitant opportunities for cost savings, property improvements, or grade developments and that the materials can be prepared using a range of fibers and minerals. Here, we: (1) report the development of new products that offer improved performance, (2) compare the performance of these new materials with that of a range of other nanocellulosic material types, (3) illustrate the performance of these new materials in reinforcement (paper and board) and viscosification applications, and (4) discuss product form requirements for different applications.





1991 ◽  
Vol 1 (3) ◽  
pp. 239-252 ◽  
Author(s):  
Harry N. Buckner ◽  
Paul E. Sojka


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