Ecological Significance of Coaggregation among Oral Bacteria

1992 ◽  
pp. 183-217 ◽  
Author(s):  
Paul E. Kolenbrander ◽  
Jack London
Author(s):  
J. E. Laffoon ◽  
R. L. Anderson ◽  
J. C. Keller ◽  
C. D. Wu-Yuan

Titanium (Ti) dental implants have been used widely for many years. Long term implant failures are related, in part, to the development of peri-implantitis frequently associated with bacteria. Bacterial adherence and colonization have been considered a key factor in the pathogenesis of many biomaterial based infections. Without the initial attachment of oral bacteria to Ti-implant surfaces, subsequent polymicrobial accumulation and colonization leading to peri-implant disease cannot occur. The overall goal of this study is to examine the implant-oral bacterial interfaces and gain a greater understanding of their attachment characteristics and mechanisms. Since the detailed cell surface ultrastructure involved in attachment is only discernible at the electron microscopy level, the study is complicated by the technical problem of obtaining titanium implant and attached bacterial cells in the same ultra-thin sections. In this study, a technique was developed to facilitate the study of Ti implant-bacteria interface.Discs of polymerized Spurr’s resin (12 mm x 5 mm) were formed to a thickness of approximately 3 mm using an EM block holder (Fig. 1). Titanium was then deposited by vacuum deposition to a film thickness of 300Å (Fig. 2).


2005 ◽  
Vol 35 (9) ◽  
pp. 48
Author(s):  
MICHELE G. SULLIVAN

2020 ◽  
Vol 6 (2) ◽  
pp. 64-68
Author(s):  
Nondira Khondhodjayeva ◽  
◽  
Nurmamat Rajabov ◽  

This article reveals the essence of the concept of "pheromones" and their biological significance. In the article variants of their application in agriculture for struggle against insects-pests are presented. The definition of term and classification of pheromones and their types are given: feromons of insects, feromons of fish, feromons of vertebrates, feromons of humans, fermons of plants, sexual feromons, anxiety feromons, trace feromons, epidemic feromons and their functions and significance for the representative's organism and the environment as a whole


1970 ◽  
Vol 11 (1) ◽  
Author(s):  
S. Kishore

Palaeocene limestone of the Ninniyur Formation of the Cauvery Basin contains abundant well-preserved calcareous algae. These various types of calcareous algal seem to be controlled by the characteristics of each type environments in which they developed and thus they provide useful palaeo-ecological information of the Ninniyur Formation. The distribution patterns of these groups of calcareous algae, extending from tidal flat to reefal environments have been observed in the Palaeocene of the Ninniyur Formation, Cauvery Basin South India. Key words: Ninniyur formation, Calcareous algae, Palaeoecology. Ecoprint Vol.11(1) 2004.


2013 ◽  
Vol 37 (7) ◽  
pp. 691-698 ◽  
Author(s):  
Le LI ◽  
Hui ZENG ◽  
Da-Li GUO

2019 ◽  
Vol 16 (3) ◽  
pp. 290-296 ◽  
Author(s):  
Dikdik Kurnia ◽  
Eti Apriyanti ◽  
Cut Soraya ◽  
Mieke H. Satari

Background: A significant number of antibiotics are known to inhibit peptidoglycan synthesis in the cross-linking stage, while the drug fosfomycin is the only one known to inhibit MurA. Escalated antibiotic resistance has had an impact on the efficacy of fosfomycin, thus demanding the discovery of suitable substitutes with improved potential for MurA inhibition. The aim of this work is to isolate antibacterial compounds from Sarang Semut (Myrmecodia pendans) and to evaluate their antibacterial activity against pathogenic oral bacteria of Enterococcus faecalis ATCC 29212 and inhibitory activity against MurA enzyme. Methods: The antibacterial compounds from Sarang Semut were isolated by a bioactivity-guided separation method with various solvents and combination of column chromatography on normal and reverse phases. The compounds with concentrations of 1000 and 5000 ppm were assessed against E. faecalis ATCC 29212 by agar well diffusion method, with chlorhexidine and fosfomycin being used as positive controls. Results: Two antibacterial compounds isolated from Sarang Semut were identified as two new flavonoids derivates of 1 (10 mg) and 2 (4 mg). Both compounds were tested for antibacterial activities against E. faecalis. MIC values of compounds 1 and 2 were 8.15 and 8.05 mm at 1000 ppm and 8.62 and 8.55 mm at 5000 ppm, respectively. MBC values were 156 and 625 ppm for 1 and 625 and 2500 ppm for 2, respectively. In an inhibitory murA enzyme activity assay, compounds 1 and 2 were shown to inhibit the enzyme activity by IC50 values of 21.7 and 151.3 ppm. Conclusion: The study demonstrated that ethyl acetate fraction of Sarang Semut contained antibacterial flavonoids as active constituents that showed activity against E. faecalis. These results showed the plant’s potential in herbal medicine and the development of new antibacterial agent for pathogenic dental caries.


Author(s):  
Ciro Gargiulo Isacco ◽  
Andrea Ballini ◽  
Danila De Vito ◽  
Kieu Cao Diem Nguyen ◽  
Stefania Cantore ◽  
...  

: The current treatment and prevention of oral disorders follow a very sectoral control and procedures considering mouth and its structures as system completely independent from the rest of the body. The main therapeutic approach is carried out on just to keep the levels of oral bacteria and hygiene in an acceptable range compatible with one-way vision of oral-mouth health completely separated from a systemic microbial homeostasis (eubiosis vs dysbiosis). This can negatively impact on the diagnosis of more complex systemic disease and its progression. Dysbiosis is consequence of oral and gut microbiota unbalance with consequences, as reported in current literature, in cardio vascular disease, diabetes mellitus, rheumatoid arthritis, and Alzheimer’s disease. Likewise, there is the need to highlight and develop a novel philosophical approach in the treatments for oral diseases that will necessarily involve non-conventional approaches.


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