Oxidative Injury Caused by Cigarette Smoking and Air Pollution

Author(s):  
Andrew J. Ghio
2020 ◽  
Vol 223 ◽  
pp. 117266 ◽  
Author(s):  
Shengzhi Sun ◽  
Wangnan Cao ◽  
King-Pan Chan ◽  
Jinjun Ran ◽  
Yang Ge ◽  
...  

1968 ◽  
Vol 54 (1) ◽  
pp. 99-111
Author(s):  
Francesco Scanga ◽  
Ennio Prozzo

The public health problems relevant for the general population which are raised by environmental contaminations with carcinogenic factors are reviewed. The discussion includes ionizing radiations, drugs, air pollution and tobacco smoke. The recent Italian legislation on air pollution control and the Italian situation concerning prevention of cigarette smoking are commented in detail.


2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Zeina Nasser ◽  
Pascale Salameh ◽  
Habib Dakik ◽  
Elias Elias ◽  
Linda Abou Abbas ◽  
...  

Outdoor air pollution is increasingly considered as a serious threat for cardiovascular diseases (CVD). The aim of this study is to investigate the association between outdoor pollutants and cardiovascular diseases among adults in Lebanon and to examine the possible moderator effect of cigarette smoking status on this association. A multicenter case-control study was conducted between October 2011 and October 2012. Cases were hospitalized patients diagnosed with CVD by a cardiologist while the control group subjects were free of any cardiac diseases. Information on sociodemographic characteristics, tobacco consumption, self-rated global health, pollution exposure, and other risk factors was collected using a questionnaire. The results of the logistic regression revealed that living near busy highway (OR 5.04, 95% CI (4.44–12.85),P<0.001) and close to local diesel generator (OR 4.76, 95% CI (2.07–10.91),P<0.001) was significantly associated with CVD. The association between the CVD and exposure to outside pollutants differed by cigarette smoking status. A clear difference was noted between nonsmokers and current smokers OR 4.6, 95% CI (1.10–19.25) and OR 10.11, 95% CI (7.33–20.23), respectively. Forthcoming studies are needed to clarify the potential link between outdoor air pollution and cardiovascular diseases in Lebanon. Public health interventions must be implemented to reduce air pollution and to improve air quality.


1974 ◽  
Vol 10 (6) ◽  
pp. 1226-1229 ◽  
Author(s):  
A. Nulsen ◽  
P. G. Holt ◽  
D. Keast

Author(s):  
Maybin Kalubula ◽  
Heqing Shen ◽  
Longjian Liu

Background: Lung cancer is one of the leading causes of morbidity and mortality worldwide with 25% of deaths due to lung cancer occurring in Europe. This study therefore sought to assess the burden of lung cancer by country and to evaluate the magnitude of fine Particulate Matter (PM2.5) and cigarette smoking by country in Europe. Methods: An ecological study nested on the World Health Organization air pollution database 2016 was conducted. We sampled 30 European Countries, with a total of 1625 mean annual samples of Particulate Matter (PM2.5) collected from 1625 designated sites (n = 1625). We further used the &lsquo;World Health Disease Rankings&rsquo; database to extract Lung Cancer Morbidity and Mortality Rate by country. We used SAS version 9.4 to indicate the distribution of PM2.5 and Lung Cancer Mortality Rate. Results: Lung cancer Relative Risk (RR) was 1.0 in all never- smokers. RR for Ex-smokers for Adeno carcinoma was 3.5 in males and 1.1 in females, small cell carcinoma was 16.2 in males and 3.8 in females. RR for current smokers for Adeno carcinoma was 8.0 in males and 4.1 in females, small cell carcinoma was 57.9 in males and 18.2 in females. Mean annual PM2.5 by country ranged from 6.01 to 37.28&micro;g/m3 whereas lung cancer mortality rate by country ranged from 19.67 to 54.26 deaths per 100,000 population. Conclusion: Cigarette smoking and exposure to both second hand smoke and high concentration of PM2.5 resulted into increased burden of lung cancer in Europe. Countries should re-strategize to reduce the burden of lung cancer in Europe.


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