scholarly journals Outdoor Air Pollution and Cardiovascular Diseases in Lebanon: A Case-Control Study

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Zeina Nasser ◽  
Pascale Salameh ◽  
Habib Dakik ◽  
Elias Elias ◽  
Linda Abou Abbas ◽  
...  
Keyword(s):  
Air Pollution ◽  
Cardiovascular Diseases ◽  
Cigarette Smoking ◽  
Case Control Study ◽  
Smoking Status ◽  
Case Control ◽  
Outdoor Air ◽  
Moderator Effect ◽  
Outdoor Air Pollution ◽  
Control Study

Outdoor air pollution is increasingly considered as a serious threat for cardiovascular diseases (CVD). The aim of this study is to investigate the association between outdoor pollutants and cardiovascular diseases among adults in Lebanon and to examine the possible moderator effect of cigarette smoking status on this association. A multicenter case-control study was conducted between October 2011 and October 2012. Cases were hospitalized patients diagnosed with CVD by a cardiologist while the control group subjects were free of any cardiac diseases. Information on sociodemographic characteristics, tobacco consumption, self-rated global health, pollution exposure, and other risk factors was collected using a questionnaire. The results of the logistic regression revealed that living near busy highway (OR 5.04, 95% CI (4.44–12.85),P<0.001) and close to local diesel generator (OR 4.76, 95% CI (2.07–10.91),P<0.001) was significantly associated with CVD. The association between the CVD and exposure to outside pollutants differed by cigarette smoking status. A clear difference was noted between nonsmokers and current smokers OR 4.6, 95% CI (1.10–19.25) and OR 10.11, 95% CI (7.33–20.23), respectively. Forthcoming studies are needed to clarify the potential link between outdoor air pollution and cardiovascular diseases in Lebanon. Public health interventions must be implemented to reduce air pollution and to improve air quality.

scholarly journals Parkinson's disease and long-term exposure to outdoor air pollution: A matched case-control study in the Netherlands

2019 ◽  
Vol 129 ◽  
pp. 28-34 ◽  
Author(s):  
Rosario Toro ◽  
George S. Downward ◽  
Marianne van der Mark ◽  
Maartje Brouwer ◽  
Anke Huss ◽  
...  
Keyword(s):  
Air Pollution ◽  
The Netherlands ◽  
Case Control Study ◽  
Case Control ◽  
Outdoor Air ◽  
Outdoor Air Pollution ◽  
Matched Case ◽  
Matched Case Control Study ◽  
Control Study

scholarly journals Parkinson'S Disease And Long-Term Exposure To Outdoor Air Pollution: A Matched Case-Control Study In The Netherlands.

2015 ◽  
Vol 2015 (1) ◽  
pp. 1075
Author(s):  
Rosario Toro Campos ◽  
Meinie Seelen ◽  
Gerard Hoek ◽  
Marianne Van Der Mark ◽  
Peter Nijssen ◽  
...  
Keyword(s):  
Air Pollution ◽  
The Netherlands ◽  
Case Control Study ◽  
Case Control ◽  
Outdoor Air ◽  
Outdoor Air Pollution ◽  
Matched Case ◽  
Matched Case Control Study ◽  
Control Study

scholarly journals Residential Radon Exposure and Cigarette Smoking in Association with Lung Cancer: A Matched Case-Control Study in Korea

2020 ◽  
Vol 17 (8) ◽  
pp. 2946
Author(s):  
Eung Joo Park ◽  
Hokyou Lee ◽  
Hyeon Chang Kim ◽  
Seung Soo Sheen ◽  
Sang Baek Koh ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cigarette Smoking ◽  
Case Control Study ◽  
Smoking Status ◽  
Case Control ◽  
Radon Exposure ◽  
Matched Case ◽  
Matched Case Control Study ◽  
Control Study ◽  
Residential Radon

Residential radon exposure and cigarette smoking are the two most important risk factors for lung cancer. The combined effects thereof were evaluated in a multi-center matched case-control study in South Korea. A total of 1038 participants were included, comprising 519 non-small cell lung cancer cases and 519 age- and sex- matched community-based controls. Residential radon levels were measured for all participants. Multivariate logistic regression was used to calculate odds ratios (OR) for lung cancer according to radon exposure (high ≥ 100 Bq/m3 vs. low < 100 Bq/m3), smoking status, and combinations of the two after adjusting for age, sex, indoor hours, and other housing information. The median age of the participants was 64 years, and 51.3% were women. The adjusted ORs (95% confidence intervals [CIs]) for high radon and cigarette smoking were 1.56 (1.03–2.37) and 2.53 (1.60–3.99), respectively. When stratified according to combinations of radon exposure and smoking status, the adjusted ORs (95% CIs) for lung cancer in high-radon non-smokers, low-radon smokers, and high-radon smokers were 1.40 (0.81–2.43), 2.42 (1.49–3.92), and 4.27 (2.14–8.52), respectively, with reference to low-radon non-smokers. Both residential radon and cigarette smoking were associated with increased odds for lung cancer, and the difference in ORs according to radon exposure was much greater in smokers than in non-smokers.

scholarly journals Residential Radon Exposure and Cigarette Smoking in Association with Lung Cancer: a Matched Case-control Study in Korea

2019 ◽  
Author(s):  
Eung Joo Park ◽  
Hokyou Lee ◽  
Hyeon Chang Kim ◽  
Seung soo Sheen ◽  
Sang Baek Koh ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cigarette Smoking ◽  
Case Control Study ◽  
Smoking Status ◽  
Case Control ◽  
Radon Exposure ◽  
Matched Case ◽  
Matched Case Control Study ◽  
Control Study ◽  
Residential Radon

Abstract Background: Residential radon exposure and cigarette smoking are the two most important risk factors for lung cancer. The combined effects thereof were evaluated in a multi-center matched case-control study in South Korea.Methods: A total of 1,038 participants were included, comprising 519 non-small cell lung cancer cases and 519 age- and sex- matched community-based controls. Residential radon levels were measured for all participants. Multivariate logistic regression was used to calculate odds ratios (OR) for lung cancer according to radon exposure (high ≥100 Bq/m3 vs. low <100 Bq/m3), smoking status, and combinations of the two after adjusting for age, sex, indoor hours, and other housing information.Results: The median age of the participants was 64 years, and 51.3% were women. The adjusted ORs (95% confidence intervals [CIs]) for high radon and cigarette smoking were 1.56 (1.03-2.37) and 2.53 (1.60-3.99), respectively. When stratified according to combinations of radon exposure and smoking status, the adjusted ORs (95% CIs) for lung cancer in high-radon non-smokers, low-radon smokers, and high-radon smokers were 1.40 (0.81-2.43), 2.42 (1.49-3.92), and 4.27 (2.14-8.52), respectively, with reference to low-radon non-smokers.Conclusion: Both residential radon and cigarette smoking were associated with increased odds for lung cancer, and the difference in ORs according to radon exposure was much greater in smokers than in non-smokers.

scholarly journals Early childhood traffic-related air pollution and risk of allergic rhinitis at 2–4 years of age modification by family stress and male gender: a case-control study in Shenyang, China

2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Shuai Hao ◽  
Fang Yuan ◽  
Pai Pang ◽  
Bo Yang ◽  
Xuejun Jiang ◽  
...  
Keyword(s):  
Air Pollution ◽  
Allergic Rhinitis ◽  
Preschool Children ◽  
Case Control Study ◽  
Family Stress ◽  
Case Control ◽  
Male Gender ◽  
Exposure Level ◽  
Early Exposure ◽  
Control Study

Abstract Background Few studies have explored the modifications by family stress and male gender in the relationship between early exposure to traffic-related air pollution (TRAP) and allergic rhinitis (AR) risk in preschool children. Methods We conducted a case-control study of 388 children aged 2–4 years in Shenyang, China. These children AR were diagnosed by clinicians. By using measured concentrations from monitoring stations, we estimated the exposures of particulate matter less than 10 μm in diameter (PM10), nitrogen dioxide (NO2), ozone (O3), carbon monoxide (CO), and sulfur dioxide (SO2) in preschool children aged 2–4 years. After adjusted potential confounding factors, we used logistic regression model to evaluate the odds ratio (OR) and 95% confidence interval (CI) for childhood AR with exposure to different air pollutants according to the increasing of the interquartile range (IQR) in the exposure level. Results The prevalence of AR in children aged 2–4 years (6.4%) was related to early TRAP exposure. With an IQR (20 μg/m3) increase in PM10 levels, an adjusted OR was significantly elevated by 1.70 (95% CI, 1.19 to 2.66). Also, with an IQR (18 μg/m3) increase in NO2, an elevated adjusted OR was 1.85 (95% CI, 1.52 to 3.18). Among children with family stress and boys, PM10 and NO2 were positively related to AR symptoms. No significant association was found among children without family stress and girls. Conclusions Family stress and male gender may increase the risk of AR in preschool children with early exposure to PM10 and NO2.

scholarly journals Ambient air pollution exposures and risk of rheumatoid arthritis: results from the Swedish EIRA case–control study

2012 ◽  
Vol 72 (6) ◽  
pp. 888-894 ◽  
Author(s):  
Jaime E Hart ◽  
Henrik Källberg ◽  
Francine Laden ◽  
Tom Bellander ◽  
Karen H Costenbader ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Air Pollution ◽  
Case Control Study ◽  
Ambient Air ◽  
Case Control ◽  
Ambient Air Pollution ◽  
Control Study

scholarly journals Association between traffic-related air pollution and asthma in preschool children in a national Japanese nested case–control study

BMJ Open ◽  
2016 ◽  
Vol 6 (2) ◽  
pp. e010410 ◽  
Author(s):  
Hideki Hasunuma ◽  
Tosiya Sato ◽  
Tsutomu Iwata ◽  
Yoichi Kohno ◽  
Hiroshi Nitta ◽  
...  
Keyword(s):  
Air Pollution ◽  
Preschool Children ◽  
Case Control Study ◽  
Case Control ◽  
Nested Case Control ◽  
Control Study

scholarly journals Association of Cystathionine β-Synthase Gene Polymorphisms With Preeclampsia

2018 ◽  
Vol 24 (9_suppl) ◽  
pp. 285S-293S ◽  
Author(s):  
Mercedes Piedad de León Bautista ◽  
Mirza Romero-Valdovinos ◽  
Beatriz Zavaleta-Villa ◽  
Arony Martínez-Flores ◽  
Angélica Olivo-Díaz
Keyword(s):  
Risk Factor ◽  
Cardiovascular Diseases ◽  
Base Pair ◽  
Gene Polymorphisms ◽  
Case Control Study ◽  
High Plasma ◽  
Case Control ◽  
Related Factor ◽  
Mexican Women ◽  
Control Study

Preeclampsia (PE) is a pregnancy disorder that increases maternal and fetal morbidity and mortality worldwide. High plasma levels of homocysteine (Hcy) are a risk factor for several cardiovascular diseases. Cystathionine β-synthase (CBS) plays an important role in Hcy homeostasis catalyzing the irreversible degradation of Hcy to cystathionine, protecting the endothelium from injury caused by hypoxia. Several mutations and polymorphisms may alter the expression of the CBS gene, resulting in variable levels of Hcy. The purpose of this study was to investigate the association of CBS gene polymorphisms with PE in Mexican women. A case–control study consisting of 129 pregnant women with PE (37 severe and 92 mild) and 173 women with uncomplicated pregnancies was performed. Polymorphisms, such as G797A, C785T, T833C, G919A, T959C, C1105T, and 844ins68 base pair, in the CBS gene were genotyped. The polymorphism G797A was monomorphic in cases with the presence of only G797A-G allele. Allele C785T-T and genotype C785T-C/T were associated with susceptibility in severe and mild PE. Alleles G797A-G and T959C-T were associated with susceptibility only in severe PE. Haplotype TGTWGTC was of susceptibility for severe PE and of protection for mild PE. Haplotypes CGTWGCC and CATWGTC seem to be protective for severe PE, but the latter is related to susceptibility in mild PE. The results suggest that C785T, G797A, and T959C mutations are contributing in different ways in severe and mild PE in our population and could be count as another related factor for this disease.

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