Light Regulation of Brassinosteroid Signaling Components: Checking Regulation of Protein Stability in Darkness

2017 ◽  
pp. 31-38
Author(s):  
Claudia Corvalán ◽  
Sunghwa Choe
Keyword(s):  
Protein Stability ◽  
Light Regulation ◽  
Brassinosteroid Signaling ◽  
Signaling Components

scholarly journals State-of-the-Art Technologies for Understanding Brassinosteroid Signaling Networks

2020 ◽  
Vol 21 (21) ◽  
pp. 8179
Author(s):  
Haijiao Wang ◽  
Song Song ◽  
Huaqiang Cheng ◽  
Yan-Wen Tan
Keyword(s):  
Signaling Pathway ◽  
Single Molecule ◽  
New Technologies ◽  
Kinase Inhibitor ◽  
Signaling Networks ◽  
Plant Signaling ◽  
The Past ◽  
Brassinosteroid Signaling ◽  
Signaling Components

Brassinosteroids, the steroid hormones of plants, control physiological and developmental processes through its signaling pathway. The major brassinosteroid signaling network components, from the receptor to transcription factors, have been identified in the past two decades. The development of biotechnologies has driven the identification of novel brassinosteroid signaling components, even revealing several crosstalks between brassinosteroid and other plant signaling pathways. Herein, we would like to summarize the identification and improvement of several representative brassinosteroid signaling components through the development of new technologies, including brassinosteroid-insensitive 1 (BRI1), BRI1-associated kinase 1 (BAK1), BR-insensitive 2 (BIN2), BRI1 kinase inhibitor 1 (BKI1), BRI1-suppressor 1 (BSU1), BR signaling kinases (BSKs), BRI1 ethyl methanesulfonate suppressor 1 (BES1), and brassinazole resistant 1 (BZR1). Furthermore, improvement of BR signaling knowledge, such as the function of BKI1, BES1 and its homologous through clustered regularly interspaced short palindromic repeats (CRISPR), the regulation of BIN2 through single-molecule methods, and the new in vivo interactors of BIN2 identified by proximity labeling are described. Among these technologies, recent advanced methods proximity labeling and single-molecule methods will be reviewed in detail to provide insights to brassinosteroid and other phytohormone signaling pathway studies.

scholarly journals TTL Proteins Scaffold Brassinosteroid Signaling Components at the Plasma Membrane to Optimize Signal Transduction in Arabidopsis

2019 ◽  
Vol 31 (8) ◽  
pp. 1807-1828 ◽  
Author(s):  
Vítor Amorim-Silva ◽  
Álvaro García-Moreno ◽  
Araceli G. Castillo ◽  
Naoufal Lakhssassi ◽  
Alicia Esteban del Valle ◽  
...  
Keyword(s):  
Signal Transduction ◽  
Plasma Membrane ◽  
Brassinosteroid Signaling ◽  
Signaling Components

scholarly journals TTL Proteins Scaffold Brassinosteroid Signaling Components at the Plasma Membrane to Optimize Signal Transduction in Plant Cells

2018 ◽  
Author(s):  
VVtor Amorim-Silva ◽  
Alvaro Garcca-Moreno ◽  
Araceli Castillo ◽  
Naoufal Lakhssassi ◽  
Jessica PPrez-Sancho ◽  
...  
Keyword(s):  
Signal Transduction ◽  
Plasma Membrane ◽  
Plant Cells ◽  
Brassinosteroid Signaling ◽  
Signaling Components

scholarly journals The LNK Gene Family: At the Crossroad between Light Signaling and the Circadian Clock

Genes ◽  
2018 ◽  
Vol 10 (1) ◽  
pp. 2 ◽  
Author(s):  
María José de Leone ◽  
Carlos Esteban Hernando ◽  
Andrés Romanowski ◽  
Mariano García-Hourquet ◽  
Daniel Careno ◽  
...  
Keyword(s):  
Circadian Rhythms ◽  
Circadian Clock ◽  
Flowering Time ◽  
Regulation Of Gene Expression ◽  
Light Regulation ◽  
Light Signaling ◽  
Developmental Processes ◽  
The Family ◽  
Signaling Components

Light signaling pathways interact with the circadian clock to help organisms synchronize physiological and developmental processes to periodic environmental cycles. The plant photoreceptors responsible for clock resetting have been characterized, but signaling components that link the photoreceptors to the clock remain to be identified. Members of the family of NIGHT LIGHT–INDUCIBLE AND CLOCK-REGULATED (LNK) genes play key roles linking light regulation of gene expression to the control of daily and seasonal rhythms in Arabidopsis thaliana. Particularly, LNK1 and LNK2 were shown to control circadian rhythms, photomorphogenic responses, and photoperiod-dependent flowering time. Here we analyze the role of the four members of the LNK family in Arabidopsis in these processes. We found that depletion of the closely related LNK3 and LNK4 in a lnk1;lnk2 mutant background affects circadian rhythms, but not other clock-regulated processes such as flowering time and seedling photomorphogenesis. Nevertheless, plants defective in all LNK genes (lnkQ quadruple mutants) display developmental alterations that lead to increased rosette size, biomass, and enhanced phototropic responses. Our work indicates that members of the LNK family have both distinctive and partially overlapping functions, and are an essential link to orchestrate light-regulated developmental processes.

scholarly journals TTL proteins scaffold brassinosteroid signaling components at the plasma membrane to optimize signal transduction in plant cells

2018 ◽  
Author(s):  
Vítor Amorim-Silva ◽  
Álvaro García-Moreno ◽  
Araceli G. Castillo ◽  
Naoufal Lakhssassi ◽  
Jessica Pérez-Sancho ◽  
...  
Keyword(s):  
Plasma Membrane ◽  
Stress Responses ◽  
Mechanistic Model ◽  
Nuclear Accumulation ◽  
Signaling Complex ◽  
Steroidal Hormones ◽  
Brassinosteroid Signaling ◽  
Positive Regulators ◽  
Core Components ◽  
Signaling Components

AbstractBrassinosteroids (BRs) form a group of steroidal hormones essential for plant growth, development and stress responses. Here, we report that plant-specific TETRATRICOPEPTIDE THIOREDOXIN-LIKE (TTL) proteins are positive regulators of BR signaling functioning as scaffold for BR signaling components in Arabidopsis. TTL3 forms a complex with all core components involved in BR signaling, including the receptor kinase BRASSINOSTEROID INSENSITIVE1 (BRI1), the transcription factor BRASSINAZOLE RESISTANT1 (BZR1) and the phosphatase BRI1-SUPPRESSOR1 (BSU1), but excluding the co-receptor BAK1. TTL3 is mainly localized in the cytoplasm, but BR treatment increases its localization at the plasma membrane, where it strengthens the association with BR signaling components. Consistent with a role in BR signaling, mutations in TTL3 and related TTL1 and TTL4 genes cause reduced BR responsiveness. We propose a mechanistic model for BR signaling, in which cytoplasmic/nuclear BR components bound to TTL proteins are recruited to the plasma membrane upon BR perception, which in turn allows the assembly of a BR signaling complex, leading to the de-phosphorylation and nuclear accumulation of the transcription factors BZR1 and BES1.

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