Analytical Techniques Help in Emulating Biological Systems: An Explanation of Why High-Level Attention Constantly Oscillates

2020 ◽  
pp. 65-71
Author(s):  
Griselda Acosta ◽  
Eric Smith ◽  
Vladik Kreinovich
Keyword(s):  
Biological Systems ◽  
Analytical Techniques ◽  
High Level

CAN SEMIEMPIRICAL QUANTUM MODELS CALCULATE THE BINDING ENERGY OF HYDROGEN BONDING FOR BIOLOGICAL SYSTEMS?

2009 ◽  
Vol 08 (04) ◽  
pp. 691-711 ◽  
Author(s):  
FENG FENG ◽  
HUAN WANG ◽  
WEI-HAI FANG ◽  
JIAN-GUO YU
Keyword(s):  
Hydrogen Bonding ◽  
Amino Acid ◽  
Amino Acid Residue ◽  
Density Functional ◽  
Biological Systems ◽  
Binding Energies ◽  
Semiempirical Model ◽  
Hydrogen Bonded Systems ◽  
High Level ◽  
Hydrogen Bonded

A modified semiempirical model named RM1BH, which is based on RM1 parameterizations, is proposed to simulate varied biological hydrogen-bonded systems. The RM1BH is formulated by adding Gaussian functions to the core–core repulsion items in original RM1 formula to reproduce the binding energies of hydrogen bonding of experimental and high-level computational results. In the parameterizations of our new model, 35 base-pair dimers, 18 amino acid residue dimers, 14 dimers between a base and an amino acid residue, and 20 other multimers were included. The results performed with RM1BH were compared with experimental values and the benchmark density-functional (B3LYP/6-31G**/BSSE) and Möller–Plesset perturbation (MP2/6-31G**/BSSE) calculations on various biological hydrogen-bonded systems. It was demonstrated that RM1BH model outperforms the PM3 and RM1 models in the calculations of the binding energies of biological hydrogen-bonded systems by very close agreement with the values of both high-level calculations and experiments. These results provide insight into the ideas, methods, and views of semiempirical modifications to investigate the weak interactions of biological systems.

Particle Swarm Optimization Algorithm in Electromagnetics- Case Studies

2012 ◽  
pp. 72-99
Author(s):  
Arezoo Modiri ◽  
Kamran Kiasaleh
Keyword(s):  
Particle Swarm Optimization ◽  
Particle Swarm ◽  
Analytical Techniques ◽  
Pso Algorithm ◽  
Multilayer Structures ◽  
Efficient Design ◽  
Swarm Optimization ◽  
Electromagnetic Problems ◽  
Microwave Techniques ◽  
High Level

This chapter is intended to describe the vast intrinsic potential of the swarm-intelligence-based algorithms in solving complicated electromagnetic problems. This task is accomplished through addressing the design and analysis challenges of some key real-world problems, ranging from the design of wearable radiators to tumor detection tools. Some of these problems have already been tackled by solution techniques other than particle swarm optimization (PSO) algorithm, the results of which can be found in the literature. However, due to the relatively high level of complexity and randomness inherent to these problems, one has to resort to oversimplification in order to arrive at reasonable solutions utilizing analytical techniques. In this chapter, the authors discuss some recent studies that utilize PSO algorithm particularly in two emerging areas; namely, efficient design of reconfigurable radiators and permittivity estimation of multilayer structures. These problems, although unique, represent a broader range of problems in practice which employ microwave techniques for antenna design and microwave imaging.

Doping and anti-doping

2017 ◽  
Author(s):  
Alan Vernec ◽  
David Gerrard
Keyword(s):  
Analytical Techniques ◽  
Therapeutic Use ◽  
Young Athletes ◽  
Unethical Behaviour ◽  
Unique Position ◽  
The World ◽  
Athletic Team ◽  
Doping Behaviour ◽  
High Level ◽  
Scientific Framework

Doping in sport, with its connotations of unethical behaviour and harm to health, has existed since antiquity. In contemporary times, an acceleration of doping practices resulted in the eventual development of a robust legal and scientific framework now entrenched in the World Anti-Doping Code. Young athletes are not immune to the myriad pressures to excel that exist in high-level sport. Many of these athletes are subject to Anti-Doping regulations and therefore they (and their physicians) must be familiar with Anti-Doping procedures and processes, including the Prohibited List and Therapeutic Use Exemptions. Advances in analytical and non-analytical techniques and strategies have increased detection and accountability. As part of the athletic team, physicians are in a unique position to recognize vulnerabilities and signs of doping behaviour. This must enable them to positively impact the course of a young athlete’s trajectory in life.

Isotopic and nuclear analytical techniques in biological systems: A critical survey

1991 ◽  
Vol 63 (9) ◽  
pp. 1269-1270 ◽  
Author(s):  
K. S. Kasprzak ◽  
L. Dencker ◽  
B. S. Larsson ◽  
R. d'Argy ◽  
S. Ullberg ◽  
...  
Keyword(s):  
Biological Systems ◽  
Analytical Techniques ◽  
Critical Survey ◽  
Nuclear Analytical Techniques ◽  
Nuclear Analytical

scholarly journals Arahan Mitigasi Bencana Kawasan Rawan Longsor Di Kabupaten Sinjai

2021 ◽  
Vol 1 (2) ◽  
pp. 196-203
Author(s):  
Muhammad Hanif Zahran ◽  
Agus Salim ◽  
Tri Budiharto
Keyword(s):  
Land Use ◽  
Quantitative Research ◽  
Analytical Techniques ◽  
Physical Conditions ◽  
Spatial Use ◽  
High Level ◽  
Descriptive Qualitative

Abstract. This study aims to identify areas prone to landslides in Sinjai Regency and propose directions for the use of landslide prone areas according to the level of landslide vulnerability in Sinjai Regency based on mitigation. This study uses quantitative research with analytical techniques used including basic physical conditions, vegetation, superimpose, and descriptive qualitative. The results showed that the distribution of landslide-prone areas in Sinjai Regency is located in West Sinjai, South Sinjai, and Sinjai Borong Districts. From the total area, South Sinjai is a sub-district whose area is dominant and has a high level of vulnerability. Directions for spatial use based on zone typology and the level of landslide vulnerability at the research location are proposed in the form of recommendations for regulating land use, as well as forms of mitigation in the form of general recommendations in accordance with the characteristics of landslide-prone areas.   Abstrak. Penelitian ini bertujuan untuk mengindentifikasi dimana saja zona daerah rawan longsor di Kabupaten Sinjai dan mengusulkan arahan pemanfaatan ruang daerah rawan longsor menurut tingkat kerawanan longsor di Kabupaten Sinjai berbasis mitigasi. Penelitian ini menggunakan penelitian kuantitatif dengan teknik analisis yang digunakan diantaranya kondisi fisik dasar, vegetasi, superimpose, dan deskriptif kualitatif. Hasil penelitian dapat diketahui bahwa sebaran daerah rawan longsor di Kabupaten Sinjai terletak di Kecamatan Sinjai Barat, Sinjai Selatan, dan Sinjai Borong. Dimana dari total luas keseluruhan, Sinjai Selatan merupakan kecamatan yang luas wilayahnya dominan memiliki tingkat kerawanan tinggi. Arahan pemanfaatan ruang berdasarkan tipologi zona dan tingkat kerawanan longsor pada lokasi penelitian diusulkan berupa bentuk rekomendasi terhadap pengaturan penggunaan lahannya, serta bentuk mitigasinya berupa rekomendasi secara umum sesuai dengan karakteristik pada kawasan rawan bencana longsor.

In situ Analysis of the Fate and behavior of Inorganic Nanomaterials in Biological System by Synchrotron Radiation X-ray Probe Techniques

2021 ◽  
Vol 17 ◽  
Author(s):  
Shuang Zhu ◽  
Yaling Wang ◽  
Chunying Chen
Keyword(s):  
Synchrotron Radiation ◽  
Biological Systems ◽  
Analytical Techniques ◽  
High Sensitivity ◽  
Electronic Configuration ◽  
X Ray ◽  
Scanning Transmission ◽  
Inorganic Nanomaterials ◽  
And Behavior ◽  
Fate And Behavior

Background: The comprehensive understanding of nanomaterial behavior in biological systems is essential in accurately modeling and predicting nanomaterial fate and toxicity. Synchrotron radiation (SR) X-ray techniques, based on their ability to study electronic configuration, coordination geometry, or oxidative state of nanomaterials with high sensitivity and spatial resolution, have been introduced to analyze the transformation behavior of nanomaterials in biological systems. Methods: Previous research in this field are classified and summarized. Results: To start with, a brief introduction of a few widely used SR-based analytical techniques including X-ray absorption spectroscopy, X-ray fluorescence microprobe, scanning transmission X-ray microscopy and circular dichroism spectroscopy is provided. Then, the recent advances of their applications in the analysis of nanomaterial behaviors are elaborated based on different nanomaterial transformation forms such as biodistribution, biomolecule interaction, decomposition, redox reaction, and recrystallization/agglomeration. Finally, a few challenges faced in this field are proposed. Conclusion: This review summarizes the application of SR X-ray techniques in analyzing the fate of inorganic nanomaterials in biological systems. We hope it can help the readers to have a general understanding of the applications of SR-based techniques in studying nanomaterial biotransformation and to stimulate more insightful researches in relevant fields.

THE ANOMALOUS ELECTRODYNAMIC CHARACTERISTICS AND POLARIZED-ORIENTED MULTILAYER MOLECULAR STRUCTURE OF MRET-ACTIVATED WATER

2008 ◽  
Vol 07 (04n05) ◽  
pp. 223-227
Author(s):  
IGOR SMIRNOV
Keyword(s):  
Biological Systems ◽  
Water Molecules ◽  
Activation Process ◽  
State University ◽  
Significant Positive Effect ◽  
Tumor Resistance ◽  
Cell Water ◽  
High Level ◽  
Moscow State University ◽  
Positive Effect

The anomalous electrodynamic characteristics (dielectric permittivity and electrical conductivity) of MRET water subjected to applied EMF (electromagnetic field) in the area of a very low range of frequencies were discovered during experiments conducted at Moscow State University, Russia. This confirmed the high level of long range dynamic structuring of water molecules in polarized-oriented multilayer formations in activated water produced with the help of the MRET activation process. The similarity of molecular formations of cell water and MRET-activated water contributes to their compatibility, easy bioavailability and assimilation of MRET-activated water into biological systems. The introduction of MRET water into biological systems can contribute to the enhancement of the cellular transduction mechanism and the proper functioning of cells in biological systems. The significant positive effect of MRET-activated water regarding tumor resistance in animals was observed in experiments conducted on 500 mice at Kiev Institute of Experimental Pathology, Oncology and Radiobiology, Ukrainian Academy of Science.

Metallomics: Guidelines for terminology and critical evaluation of analytical chemistry approaches (IUPAC Technical Report)

2010 ◽  
Vol 82 (2) ◽  
pp. 493-504 ◽  
Author(s):  
Ryszard Lobinski ◽  
J. Sabine Becker ◽  
Hiroki Haraguchi ◽  
Bibundhendra Sarkar
Keyword(s):  
Analytical Chemistry ◽  
Metal Content ◽  
State Of The Art ◽  
Biological Systems ◽  
Critical Evaluation ◽  
Analytical Techniques ◽  
The State ◽  
Technical Report

Definitions for the terms "metallome" and "metallomics" are proposed. The state of the art of analytical techniques and methods for systematic studies of metal content, speciation, localization, and use in biological systems is briefly summarized and critically evaluated.

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