scholarly journals Middle Lands in Friuli Venezia Giulia. Research by Design and Towards Action

2020 ◽  
pp. 268-280
Author(s):  
Elena Marchigiani
Keyword(s):  
Friuli Venezia Giulia

scholarly journals AB0520 FIVE-YEAR RATE OF HOSPITALIZATIONS IN ANCA-ASSOCIATED VASCULITIDES IN THE ITALIAN REGION OF FRIULI VENEZIA GIULIA (2013-2017)

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1557.2-1558
Author(s):  
L. Quartuccio ◽  
E. Treppo ◽  
S. De Vita ◽  
F. Valent
Keyword(s):  
Health Care ◽  
Granulomatosis With Polyangiitis ◽  
Burden Of Illness ◽  
Clinical Manifestations ◽  
Administrative Databases ◽  
Eosinophilic Granulomatosis With Polyangiitis ◽  
Italian Region ◽  
Potential Health ◽  
Number Of Patients ◽  
Friuli Venezia Giulia

Background:ANCA-associated vasculitides (AAV) are a group of systemic vasculitis carrying a high risk of hospitalization because the multiorgan involvement, the acute nature of some clinical manifestations, the chronic but very disabling course of some other manifestations and finally the risk of severe infections due to chronic glucocorticoid and immunosuppressor administration. However, data on hospitalization due to ANCA-associated vasculitis are still scarce.Objectives:to estimate the rate of the first hospitalization or the death in patients suffering from AAV in the Italian region of Friuli Venezia Giulia (about 1,200,000 inhabitants) from year 2013 to 2017.Methods:integration of the information coming from many administrative databases were used to this end. The Regional Health Information System of Friuli Venezia Giulia was used as the source of information for this retrospective cohort study. The system covers the entire regional population and includes various electronic health administrative databases that can be linked with one another on an individual basis through a unique encrypted identifier. In particular, the following databases were matched: the database of the regional potential health care beneficiaries (including demographic information and the residential history of all of the subjects living in the region), the hospital discharge database, the database of exemptions from medical charges were used for this study, the database of the different regional laboratories. The population under study was selected based on the following inclusion criteria: patients were residents in Friuli Venezia Giulia and they had to carry the exemption code for AAV, including Granulomatosis with Polyangiitis (GPA), or Eosinophilic Granulomatosis with Polyangiitis (EGPA), or Microscopic Polyangiitis (MPA). This population was observed from 2013 to 2017. The coded event was the occurrence of the first hospitalization or the death. Also, all the hospitalization and their main discharge diagnoses were registered.Results:103 patient with AAV were identified. The number of patients with at least one hospitalization/death was 74/103 (71,8%). Seven patients died during the observation period (6,6%). The whole number of hospitalizations was 285 in 74 patients. 55/74 (74,3%) patients experienced more than one hospitalization. In the majority of the hospitalizations (119/285, 41,7%), the cause of hospitalization was directly attributable to the disease itself, while the second cause of hospitalization was the infections (26/285, 9,1%). In 10/103 patients (9,7%), an end stage renal disease was recorded as event. The presence of at least one positivity for ANCA antibodies was documented in 76/103 patients (73,8%), mainly in patients carrying GPA. Globally, the presence of ANCA antibody seems to be associated with greater likelihood of an event (p=0,07, log-rank test). The first event occurred in 50% of ANCA-positive patients within 180 days from diagnosis, while in 50% of ANCA negative patients in 859 days. 6 out of the 7 deaths occurred in ANCA positive patients.Conclusion:the rate of hospitalization in AAV is very high confirming the high health care burden of illness. The disease itself is often the cause of the hospitalization, as well as the infectious complication, highlighting the need for more effective treatments, and glucocorticoid sparing therapies. ANCA antibody may represent a biomarker of a more serious disease.Disclosure of Interests:Luca Quartuccio Consultant of: Abbvie, Bristol, Speakers bureau: Abbvie, Pfizer, Elena Treppo: None declared, Salvatore De Vita Consultant of: Roche, GSK, Speakers bureau: Roche, GSK, Novartis, Francesca Valent: None declared

scholarly journals What Does It Mean to Be a(n Italian) Borderland? Recent Literature on Italy's ‘New Provinces’ of South Tyrol and the Julian March

2021 ◽  
pp. 1-11
Author(s):  
Eden McLean
Keyword(s):  
Role Model ◽  
Recent Literature ◽  
Minority Populations ◽  
World War ◽  
Consociational Democracy ◽  
South Tyrol ◽  
History Of ◽  
International Role ◽  
Border Controls ◽  
Friuli Venezia Giulia

In the era of the Schengen Area (at least in the days before Covid-19), travel from Munich to Bozen/Bolzano or Ljubljana to Trst/Trieste is a decidedly unremarkable, albeit beautiful, adventure. Just as meaningful as the lack of border controls, travellers find all public signage in both Italian and German (and sometimes Ladin, too) upon arrival in Bozen/Bolzano. Signs in the streets of Trst/Trieste less reliably have Slovene alongside the Italian, but assistance with translation can be found with little difficulty. The Italian autonomous regions ‘with special statutes’ in which these cities reside – Trentino-Alto Adige (South Tyrol) and Friuli Venezia Giulia (the Julian March) – are multilingual territories that, at least on an official level, embrace a multiethnic heritage and reality. In fact, Trentino-Alto Adige's consociational democracy is widely regarded among political scientists as an international role model for how states can successfully protect and give voice to minority populations. Those unfamiliar with the more recent history of these regions might be surprised to learn of these avowedly multiethnic political and cultural structures. For much of the first half of the twentieth century, the regions’ two states – Austria-Hungary until 1919 and thereafter Italy – employed the ‘nationality principle’ to define policies and populations in these territories. As in most of Europe at the time, sovereignty was increasingly predicated on the contemporary ideal of the nation state, in which borders, ethnicity, language and citizenship were all bound together. Of course, as a multiethnic empire, Austria-Hungary was much more concerned about centralising state authority (and then fighting a world war) than national homogeneity, while Italy's nationalisation campaign in the interwar period became fundamental to its presence in the new provinces. Still, both states sought to classify and ultimately to control their border populations by privileging ethnolinguistic categories of citizenship.

Macrobenthic invertebrate energy densities and ecological status in freshwater watercourses (Friuli Venezia-Giulia, Northeast Italy)

2021 ◽  
Author(s):  
Marco Bertoli ◽  
Gabriele Piazza ◽  
Paolo Pastorino ◽  
Marino Prearo ◽  
Francesco Cozzoli ◽  
...  
Keyword(s):  
Ecological Status ◽  
Friuli Venezia Giulia

scholarly journals Prevalence of SARS-CoV-2 infection in Italian pediatric population: a regional seroepidemiological study

2021 ◽  
Vol 47 (1) ◽  
Author(s):  
Manola Comar ◽  
Simone Benvenuto ◽  
Marzia Lazzerini ◽  
Giorgio Fedele ◽  
Egidio Barbi ◽  
...  
Keyword(s):  
Pediatric Population ◽  
Cross Sectional Study ◽  
Nasopharyngeal Swab ◽  
Strongly Correlated ◽  
Igg Antibodies ◽  
Cross Sectional ◽  
Equal Distribution ◽  
Chemiluminescent Immunoassay ◽  
Italian National Institute ◽  
Friuli Venezia Giulia

Abstract Background Data on the effective burden of the SARS-CoV-2 pandemic in pediatric population are very limited, mostly because of the higher rate of asymptomatic or paucisymptomatic cases among children. Updated data on COVID-19 prevalence are needed for their relevance in public health and for infection control policies. In this single-centre cross-sectional study we aimed to assess prevalence of SARS-CoV-2 infection through IgG antibodies detection in an Italian pediatric cohort. Methods The study was conducted in January 2021 among both inpatients and outpatients referring to Research Institute for Maternal and Child Health “Burlo Garofolo” in Trieste, Friuli Venezia-Giulia, Italy, who needed for blood test for any reason. Collected samples were sent to Italian National Institute of Health for analysis through chemiluminescent immunoassay (CLIA). Results One hundred sixty-nine patients were included in the study, with a median age of 10.5 ± 4.1 years, an equal distribution for sex (49.7% female patients), and a 55.6% prevalence of comorbidities. Prevalence of anti-SARS-CoV-2 trimeric Spike protein IgG antibodies was 9.5% (n = 16), with a medium titre of 482.3 ± 387.1 BAU/mL. Having an infected cohabitant strongly correlated with IgG positivity (OR 23.83, 95% CI 7.19–78.98, p < 0.0001), while a cohabitant healthcare worker wasn’t associated with a higher risk (OR 1.53, 95% CI 0.4–5.86, p 0.46). All of the 5 patients who had previously tested positive to a nasopharyngeal swab belonged to the IgG positive group, with a 3-month interval from the infection at most. Conclusion We assessed a 9.5% SARS-CoV-2 seroprevalence in a pediatric cohort from Friuli Venezia-Giulia region in January 2021, showing a substantial increase after the second peak of the pandemic occurred starting from October 2020, compared to 1% prevalence observed by National Institute of Statistics (ISTAT) in July 2020.

scholarly journals Triterpene Acid and Phenolics from Ancient Apples of Friuli Venezia Giulia as Nutraceutical Ingredients: LC-MS Study and In Vitro Activities

Molecules ◽  
2019 ◽  
Vol 24 (6) ◽  
pp. 1109 ◽  
Author(s):  
Stefania Sut ◽  
Gokhan Zengin ◽  
Filippo Maggi ◽  
Mario Malagoli ◽  
Stefano Dall’Acqua
Keyword(s):  
Radical Scavenging ◽  
Reducing Power ◽  
Total Phenolic ◽  
Inhibitory Effects ◽  
Triterpene Acid ◽  
Beneficial Effects ◽  
Triterpene Acids ◽  
Phenolic Constituents ◽  
Friuli Venezia Giulia

Triterpene acid and phenolic constituents from nine ancient varieties of apple (Malus domestica) fruits cultivated in Fanna, Friuli Venezia Giulia region, northeast Italy, were analyzed and compared with four commercial apples (‘Golden Delicious’, ‘Red Delicious’, ‘Granny Smith’ and ‘Royal Gala’). Total phenolic and flavonoid contents were measured by spectrophotometric assays. The quali-quantitative fingerprint of secondary metabolites including triterpene acid was obtained by LC-DAD-(ESI)-MS and LC-(APCI)-MS, respectively. Based on the two LC-MS datasets, multivariate analysis was used to compare the composition of ancient fruit varieties with those of four commercial apples. Significant differences related mainly to the pattern of triterpene acids were found. Pomolic, euscaphyc, maslinic and ursolic acids are the most abundant triterpene in ancient varieties pulps and peels, while ursolic and oleanolic acids were prevalent in the commercial fruits. Also, the content of the phenolic compounds phloretin-2-O-xyloglucoside and quercetin-3-O-arabinoside was greater in ancient apple varieties. The antioxidant (radical scavenging, reducing power, metal chelating and phosphomolybdenum assays) and enzyme inhibitory effects (against cholinesterase, tyrosinase, amylase and glucosidase) of the samples were investigated in vitro. Antioxidant assays showed that the peels were more active than pulps. However, all the samples exhibited similar enzyme inhibitory effects. Ancient Friuli Venezia Giulia apple cultivars can be a source of chlorogenic acid and various triterpene acids, which are known for their potential anti-inflammatory activity and beneficial effects on lipid and glucose metabolism. Our results make these ancient varieties suitable for the development of new nutraceutical ingredients.

scholarly journals Publisher Correction: Understanding Factors Leading to Primary Cesarean Section and Vaginal Birth After Cesarean Delivery in the Friuli-Venezia Giulia Region (North-Eastern Italy), 2005–2015

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
L. Cegolon ◽  
G. Mastrangelo ◽  
G. Maso ◽  
G. Dal Pozzo ◽  
L. Ronfani ◽  
...  
Keyword(s):  
Cesarean Section ◽  
Cesarean Delivery ◽  
Vaginal Birth ◽  
Vaginal Birth After Cesarean ◽  
North Eastern ◽  
Friuli Venezia Giulia

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Viola jordaniiHanry (Violaceae), a species of conservation interest occurring in Friuli Venezia Giulia (northeast Italy)

Webbia ◽  
2014 ◽  
Vol 70 (1) ◽  
pp. 139-149 ◽  
Author(s):  
M. Castello ◽  
M. Vidali ◽  
M. Erben ◽  
F. Bolzan
Keyword(s):  
Friuli Venezia Giulia
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