The Yale Bright Bodies Lifestyle Intervention Program: An Intensive Lifestyle Intervention for Obese Children and Adolescents With and Without T2D

2021 ◽  
pp. 203-216
Author(s):  
Mary Savoye ◽  
Paulina Rose ◽  
Stephanie Samuels ◽  
William V. Tamborlane ◽  
Sonia Caprio ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Lifestyle Intervention ◽  
Intervention Program ◽  
Obese Children ◽  
Intensive Lifestyle Intervention ◽  
Lifestyle Intervention Program

scholarly journals A Comprehensive, Multidisciplinary, Personalized, Lifestyle Intervention Program is Associated with Increased Leukocyte Telomere Length in Children and Adolescents with Overweight and Obesity

Nutrients ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 2682
Author(s):  
George Paltoglou ◽  
Christina Raftopoulou ◽  
Nicolas C. Nicolaides ◽  
Sofia M. Genitsaridi ◽  
Sofia I. Karampatsou ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Telomere Length ◽  
Lifestyle Intervention ◽  
Intervention Program ◽  
Overweight And Obesity ◽  
Initial Assessment ◽  
Biological Aging ◽  
Childhood And Adolescence ◽  
Lifestyle Interventions ◽  
Lifestyle Intervention Program

Leucocyte telomere length (LTL) is a robust marker of biological aging and is associated with obesity and cardiometabolic risk factors in childhood and adolescence. We investigated the effect of a structured, comprehensive, multidisciplinary, personalized, lifestyle intervention program of healthy diet and physical exercise on LTL in 508 children and adolescents (239 males, 269 females; 282 prepubertal, 226 pubertal), aged 10.14 ± 0.13 years. Participants were classified as obese (n = 267, 52.6%), overweight (n = 174, 34.2%), or of normal BMI (n = 67, 13.2%) according to the International Obesity Task Force (IOTF) cutoff points and were studied prospectively for one year. We demonstrated that LTL increased significantly after 1 year of the lifestyle interventions, irrespective of gender, pubertal status, or body mass index (BMI). Waist circumference was the best negative predictor of LTL at initial assessment. The implementation of the lifestyle interventions also resulted in a significant improvement in clinical (BMI, BMI z-score and waist to height ratio) and body composition indices of obesity, inflammatory markers, hepatic enzymes, glycated hemoglobin (HbA1C), quantitative insulin sensitivity check index (QUICKI), and lipid profile in all participants. These findings indicate that the increased LTL may be associated with a more favorable metabolic profile and decreased morbidity later in life.

scholarly journals Effects of an intensive lifestyle intervention program on portal hypertension in patients with cirrhosis and obesity: The SportDiet study

Hepatology ◽  
2017 ◽  
Vol 65 (4) ◽  
pp. 1293-1305 ◽  
Author(s):  
Annalisa Berzigotti ◽  
Agustín Albillos ◽  
Candid Villanueva ◽  
Joan Genescá ◽  
Alba Ardevol ◽  
...  
Keyword(s):  
Portal Hypertension ◽  
Lifestyle Intervention ◽  
Intervention Program ◽  
Intensive Lifestyle Intervention ◽  
Lifestyle Intervention Program

scholarly journals The use of group dynamics strategies to enhance cohesion in a lifestyle intervention program for obese children

2009 ◽  
Vol 9 (1) ◽  
Author(s):  
Luc J Martin ◽  
Shauna M Burke ◽  
Sheree Shapiro ◽  
Albert V Carron ◽  
Jennifer D Irwin ◽  
...  
Keyword(s):  
Lifestyle Intervention ◽  
Group Dynamics ◽  
Intervention Program ◽  
Obese Children ◽  
Lifestyle Intervention Program

Markers of metabolic syndrome in obese children before and after 1-year lifestyle intervention program

2010 ◽  
Vol 50 (6) ◽  
pp. 391-400 ◽  
Author(s):  
C. Pedrosa ◽  
B. M. P. M. Oliveira ◽  
I. Albuquerque ◽  
C. Simões-Pereira ◽  
M. D. Vaz-de-Almeida ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Lifestyle Intervention ◽  
Intervention Program ◽  
Obese Children ◽  
Before And After ◽  
Lifestyle Intervention Program

scholarly journals Role of lifestyle intervention programme in regulating brain derived neurotrophic factor in obese children with metabolic syndrome components

2019 ◽  
Vol 12 (3) ◽  
pp. 1317-1328
Author(s):  
Inas R. El- Alameey ◽  
Hanaa H. Ahmed ◽  
Mones M. Abushady
Keyword(s):  
Metabolic Syndrome ◽  
Lifestyle Intervention ◽  
Intervention Program ◽  
Fasting Blood Glucose ◽  
Obese Children ◽  
Before And After ◽  
Lifestyle Intervention Program ◽  
One Year ◽  
Metabolic Syndrome Components ◽  
Serum Bdnf

Brain derived neurotrophic factor (BDNF) is a neurotrophin probably concerned in the pathophysiology of obesity and metabolic syndrome (MS) in adults. The aim was to explore serum BDNF relationship with metabolic syndrome components before and after one-year of the lifestyle intervention program in obese children. Forty obese children and forty age and gender-matched lean controls were studied. Anthropometric parameters, blood pressure, fasting blood glucose, serum insulin, lipid profile, insulin resistance (HOMA-IR), and serum BDNF, before and after one year of diet control and physical activity were measured. At baseline, fasting glucose, insulin, HOMA-IR, cholesterol, LDL, triglycerides were significantly higher in obese children relative to controls (P=0.00). Serum BDNF concentration was significantly lower in obese children than in lean controls (P=0.00), and its mean concentration of the subjects with MS was significantly lower than those without MS, and control group (P< 0.001). Linear regression analysis suggested that high waist: hip ratio, body adiposity index, fat percentage, diastolic BP, fasting blood glucose, LDL and HOMA-IR are good predictors for decreased serum BDNF concentration in obese children. After one-year intervention program, the obese group showed a significant increase in serum BDNF, and HDL, paralleled by a significant decline in fasting glucose, insulin, HOMA-IR, cholesterol, LDL, triglycerides as compared to the baseline (P =0.00). Serum BDNF was lower in obese children than in lean controls, and seemed to be linked with the metabolic syndrome components. One-year lifestyle intervention program succeeded to enhance BDNF serum concentration in these children.

Investigation of Myostatin Serum Levels Before and After a 6-Month Lifestyle Intervention Program in Obese Children

2010 ◽  
Vol 119 (04) ◽  
pp. 238-242 ◽  
Author(s):  
S. Ehehalt ◽  
R. Schweizer ◽  
G. Blumenstock ◽  
C. Pfaff ◽  
N. Schurr ◽  
...  
Keyword(s):  
Lifestyle Intervention ◽  
Intervention Program ◽  
Serum Levels ◽  
Obese Children ◽  
Before And After ◽  
Lifestyle Intervention Program
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