Malignant Tumours as Causes of Death of Former Athletes

Author(s):  
L. Schmid
2020 ◽  
pp. jclinpath-2020-207080
Author(s):  
Elias Mund ◽  
Johannes Salem ◽  
Hans H Kreipe ◽  
Kais Hussein

AimsThe number of clinical autopsies decreases while the rate of missed relevant diagnoses is known to be 2%–20%. In this study, we focused on postmortem examinations of patients after transplantation of solid organs.MethodsA total of 122 cases were assessed for this study. Transplant organs included liver (LiTx; n=42/122, 34%), heart (n=8/122, 7%), lungs (n=32/122, 26%), kidney (KTx; n=38/122, 31%) and KTx+LiTx (n=2/122, 2%).ResultsThe most frequent autopsy-verified causes of death were cardiac or respiratory failure (together n=85/122, 70%). The frequency of malignant tumours that were identified at autopsy was 5% (n=6/122). In 3% (n=4/122) of cases, Goldman class I discrepancies between clinical diagnosis and autopsy findings were identified.ConclusionsThe rate of missed relevant diagnoses might be relatively low, but these cases nevertheless refute the contention that modern diagnostic techniques negate the need for autopsies in patients who died after transplantation.


2019 ◽  
Vol 121 (10) ◽  
pp. 883-889 ◽  
Author(s):  
Kwok F. Wong ◽  
Paul C. Lambert ◽  
Sarwar I. Mozumder ◽  
John Broggio ◽  
Mark J. Rutherford

Abstract Background Cancer survival statistics are typically reported by using measures discounting the impact of other-cause mortality, such as net survival. This is a hypothetical measure and is interpreted as excluding the possibility of cancer patients dying from other causes. Crude probability of death partitions the all-cause probability of death into deaths from cancer and other causes. Methods The National Cancer Registration and Analysis Service is the single cancer registry for England. In 2006–2015, 1,590,477 malignant tumours were diagnosed for breast, colorectal, lung, melanoma and prostate cancer in adults. We used a relative survival framework, with a period approach, providing estimates for up to 10-year survival. Mortality was partitioned into deaths due to cancer or other causes. Unconditional and conditional (on surviving 1-years and 5-years) crude probability of death were estimated for the five cancers. Results Elderly patients who survived for a longer period before dying were more likely to die from other causes of death (except for lung cancer). For younger patients, deaths were almost entirely due to the cancer. Conclusion There are different measures of survival, each with their own strengths and limitations. Careful choices of survival measures are needed for specific scenarios to maximise the understanding of the data.


2006 ◽  
Vol 5 (1) ◽  
pp. 188-189
Author(s):  
M ANASTASIU ◽  
C MIHAI ◽  
C CALTEA ◽  
C SINESCU

Crisis ◽  
2009 ◽  
Vol 30 (1) ◽  
pp. 6-12 ◽  
Author(s):  
D.P. Doessel ◽  
Ruth F.G. Williams ◽  
Harvey Whiteford

Background. Concern with suicide measurement is a positive, albeit relatively recent, development. A concern with “the social loss from suicide” requires careful attention to appropriately measuring the phenomenon. This paper applies two different methods of measuring suicide data: the conventional age-standardized suicide (count) rate; and the alternative rate, the potential years of life lost (PYLL) rate. Aims. The purpose of applying these two measures is to place suicide in Queensland in a historical and comparative (relative to other causes of death) perspective. Methods. Both measures are applied to suicide data for Queensland since 1920. These measures are applied also to two “largish” causes of death and two “smaller” causes of death, i.e., circulatory diseases, cancers, motor vehicle accidents, suicide. Results. The two measures generate quite different pictures of suicide in Queensland: Using the PYLL measure, suicide is a quantitatively larger issue than is indicated by the count measure. Conclusions. The PYLL measure is the more appropriate measure for evaluation exercise of public health prevention strategies. This is because the PYLL measure is weighted by years of life lost and, thus, it incorporates more information than the count measure which implicitly weights each death with a somewhat partial value, viz. unity.


Author(s):  
Nadine R. Sahyoun ◽  
Harold Lentzner ◽  
Donna Hoyert ◽  
Kristen N. Robinson
Keyword(s):  

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