Novel indices of oxidant stress in cardiovascular disease: specific analysis of F2-isoprostanes

1997 ◽  
pp. 25-41
Author(s):  
Domenico Praticò ◽  
Murdeach Reilly ◽  
John A. Lawson ◽  
Garret A. FitzGerald
Keyword(s):  
Cardiovascular Disease ◽  
Oxidant Stress ◽  
Specific Analysis ◽  
Disease Specific

scholarly journals Personalized Proteomics for Precision Diagnostics in Hearing Loss: Disease-Specific Analysis of Human Perilymph by Mass Spectrometry

ACS Omega ◽  
2021 ◽  
Author(s):  
Heike A. Schmitt ◽  
Andreas Pich ◽  
Nils K. Prenzler ◽  
Thomas Lenarz ◽  
Jennifer Harre ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Hearing Loss ◽  
Specific Analysis ◽  
Disease Specific

Is Any Cardiovascular Disease-Specific DNA Methylation Biomarker Within Reach?

2020 ◽  
Vol 22 (10) ◽  
Author(s):  
Carmen de la Rocha ◽  
Silvio Zaina ◽  
Gertrud Lund
Keyword(s):  
Cardiovascular Disease ◽  
Dna Methylation ◽  
Disease Specific

scholarly journals Mediating-Moderating Effect of Allostatic Load on the Association between Dietary Approaches to Stop Hypertension Diet and All-Cause and Cause-Specific Mortality: 2001–2010 National Health and Nutrition Examination Surveys

Nutrients ◽  
2019 ◽  
Vol 11 (10) ◽  
pp. 2311 ◽  
Author(s):  
Hind A. Beydoun ◽  
Shuyan Huang ◽  
May A. Beydoun ◽  
Sharmin Hossain ◽  
Alan B. Zonderman
Keyword(s):  
Cardiovascular Disease ◽  
Allostatic Load ◽  
Moderating Effects ◽  
Dash Diet ◽  
Health And Nutrition ◽  
All Cause Mortality ◽  
Specific Mortality ◽  
Disease Specific Mortality ◽  
Cancer Specific Mortality ◽  
Disease Specific

This secondary analysis of survey data examined mediating-moderating effects of allostatic load score (calculated using the Rodriquez method) on the association between nutrient-based Dietary Approaches to Stop Hypertension (DASH) diet score (Mellen Index) and the all-cause and cause-specific mortality risks among 11,630 adults ≥ 30 years of age from the 2001–2010 National Health and Nutrition Examination Surveys with no history of cardiovascular disease or cancer at baseline, and who were followed-up for ~9.35 years. Multivariable models were adjusted for demographic, socioeconomic, lifestyle, and health characteristics. All-cause, cardiovascular disease, and cancer-specific mortality rates were estimated at 6.5%, 1.1%, and 1.9%, respectively. The median DASH total score was 3.0 (range: 1–8) (with 78.3% scoring < 4.5), whereas the median allostatic load score was 3 (range: 0–9). The DASH diet, fiber, and magnesium were negatively correlated with allostatic load, whereas allostatic load predicted higher all-cause mortality, irrespective of the DASH diet. Whereas protein was protective, potassium increased all-cause mortality risk, irrespective of allostatic load. Potassium was protective against cardiovascular disease-specific mortality but was a risk factor for cancer-specific mortality. Although no moderating effects were observed, mediation by the allostatic load on cardiovascular disease-specific mortality was observed for DASH total score and selected component scores. Direct (but not indirect) effects of DASH through the allostatic load were observed for all-cause mortality, and no direct or indirect effects were observed for cancer-specific mortality. From a public health standpoint, the allostatic load may be a surrogate for the preventive effects of the DASH diet and its components on cardiovascular disease-specific mortality risk.

Dairy products, surrogate markers, and cardiovascular disease; a sex-specific analysis from the ATTICA prospective study

2020 ◽  
Vol 30 (12) ◽  
pp. 2194-2206
Author(s):  
Matina Kouvari ◽  
Demosthenes B. Panagiotakos ◽  
Christina Chrysohoou ◽  
Ekavi N. Georgousopoulou ◽  
Mary Yannakoulia ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Prospective Study ◽  
Dairy Products ◽  
Surrogate Markers ◽  
Specific Analysis

scholarly journals Adolescent Body Mass Index and Cardiovascular Disease–Specific Mortality by Midlife

2017 ◽  
Vol 102 (8) ◽  
pp. 3011-3020 ◽  
Author(s):  
Gilad Twig ◽  
Dana Ben-Ami Shor ◽  
Ariel Furer ◽  
Hagai Levine ◽  
Estela Derazne ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Body Mass Index ◽  
Body Mass ◽  
Specific Mortality ◽  
Disease Specific Mortality ◽  
Disease Specific

The role of oxidant stress in angiotensin II-mediated contraction of human resistance arteries in the state of health and the presence of cardiovascular disease

2006 ◽  
Vol 45 (6) ◽  
pp. 395-399 ◽  
Author(s):  
Monira B. Hussain ◽  
Valentina O. Püntmann ◽  
Manuel Mayr ◽  
Teck Khong ◽  
Donald R.J. Singer
Keyword(s):  
Cardiovascular Disease ◽  
Angiotensin Ii ◽  
Oxidant Stress ◽  
The State ◽  
State Of Health ◽  
Resistance Arteries

scholarly journals Plasma YKL-40 and Total and Disease-Specific Mortality in the General Population

2010 ◽  
Vol 56 (10) ◽  
pp. 1580-1591 ◽  
Author(s):  
Julia S Johansen ◽  
Stig E Bojesen ◽  
Anne Tybjærg-Hansen ◽  
Anne K Mylin ◽  
Paul A Price ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
General Population ◽  
Early Death ◽  
Mortality Rates ◽  
Term Survival ◽  
Hazard Ratios ◽  
Heart Study ◽  
Specific Mortality ◽  
Disease Specific Mortality ◽  
Disease Specific

BACKGROUND Increased plasma YKL-40 is associated with short-term survival in patients with cardiovascular disease and cancer. We tested the hypothesis that increased plasma YKL-40 is associated with total and disease-specific mortality in the general population. METHODS We measured plasma YKL-40 in 8899 study participants, aged 20–95 years, in the Copenhagen City Heart Study from the Danish general population who were followed for 16 years: 3059 died, 2158 had ischemic cardiovascular disease, 2271 had cancer, and 2820 had other diseases associated with increased YKL-40. Hazard ratios for early death and absolute 10-year mortality rates were calculated according to plasma YKL-40 percentile groupings computed within sex and age decade: 0%–33%, 34%–66%, 67%–90%, 91%–95%, and 96%–100%. RESULTS Median survival age decreased from 83 years for participants with plasma YKL-40 in category 0%–33% to 69 years in category 96%–100% (trend, P &lt; 0.0001). Risk of early death was increased (multifactorially adjusted hazard ratios) by 10% for YKL-40 category 34%–66%, by 30% for 67%–90%, by 70% for 91%–95%, and by 90% for 96%–100% vs YKL-40 category 0%–33% (trend, P &lt; 0.0001). Corresponding increases in participants with ischemic cardiovascular disease were 10%, 20%, 80%, and 60% (P &lt; 0.0001); in those with cancer were 10%, 20%, 50%, and 70% (P &lt; 0.0001); and in those with other diseases were 10%, 20%, 40%, and 60% (P &lt; 0.0001). Highest absolute 10-year mortality rates were 78% and 90% in women and men, respectively, who were &gt;70 years old, smoked, and were in YKL-40 category 96%–100%. CONCLUSIONS Increased plasma YKL-40 is associated with risk of early death from cardiovascular disease, cancer, and other diseases in the general population.

Sign in / Sign up

Export Citation Format

Share Document