Dairy products, surrogate markers, and cardiovascular disease; a sex-specific analysis from the ATTICA prospective study

2020 ◽  
Vol 30 (12) ◽  
pp. 2194-2206
Author(s):  
Matina Kouvari ◽  
Demosthenes B. Panagiotakos ◽  
Christina Chrysohoou ◽  
Ekavi N. Georgousopoulou ◽  
Mary Yannakoulia ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Prospective Study ◽  
Dairy Products ◽  
Surrogate Markers ◽  
Specific Analysis

scholarly journals Consumption of dairy products and cardiovascular disease risk: results from the French prospective cohort NutriNet-Santé

2021 ◽  
pp. 1-37
Author(s):  
Laury Sellem ◽  
Bernard Srour ◽  
Kim G. Jackson ◽  
Serge Hercberg ◽  
Pilar Galan ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Dairy Products ◽  
Disease Risk ◽  
Heart Diseases ◽  
Cardiovascular Disease Risk ◽  
Dietary Intakes ◽  
Cvd Risk ◽  
Dairy Consumption ◽  
Fermented Dairy ◽  
The Impact

Abstract In France, dairy products contribute to dietary saturated fat intake, of which reduced consumption is often recommended for cardiovascular disease (CVD) prevention. Epidemiological evidence on the association between dairy consumption and CVD risk remains unclear, suggesting either null or inverse associations. This study aimed to investigate the associations between dairy consumption (overall and specific foods) and CVD risk in a large cohort of French adults. This prospective analysis included participants aged ≥ 18 years from the NutriNet-Santé cohort (2009–2019). Daily dietary intakes were collected using 24h-dietary records. Total dairy, milk, cheese, yogurts, fermented and reduced-fat dairy intakes were investigated. CVD cases (n=1,952) included cerebrovascular (n=878 cases) and coronary heart diseases (CHD, n=1,219 cases). Multivariable Cox models were performed to investigate associations. This analysis included n=104,805 French adults (mean age at baseline 42.8 years (SD 14.6)), mean follow-up 5.5 years (SD 3.0, i.e. 579,155 persons years). There were no significant associations between dairy intakes and total CVD or CHD risks. However, the consumption of at least 160 g/d of fermented dairy (e.g. cheese and yogurts) was associated with a reduced risk of cerebrovascular diseases compared to intakes below 57 g/d (HR=0.81 [0.66-0.98], p-trend=0.01). Despite being a major dietary source of saturated fats, dairy consumption was not associated with CVD or CHD risks in this study. However, fermented dairy was associated with a lower cerebrovascular disease risk. Robust randomized controlled trials are needed to further assess the impact of consuming different dairy foods on CVD risk and potential underlying mechanisms.

scholarly journals Association of Major Dietary Protein Sources With All‐Cause and Cause‐Specific Mortality: Prospective Cohort Study

2021 ◽  
Author(s):  
Yangbo Sun ◽  
Buyun Liu ◽  
Linda G. Snetselaar ◽  
Robert B. Wallace ◽  
Aladdin H. Shadyab ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Dairy Products ◽  
Protein Intake ◽  
Lower Risk ◽  
Red Meat ◽  
Cardiovascular Disease Mortality ◽  
Protein Sources ◽  
Disease Mortality ◽  
All Cause Mortality ◽  
Processed Red Meat

Background Dietary recommendations regarding protein intake have been focused on the amount of protein. However, such recommendations without considering specific protein sources may be simplistic and insufficient. Methods and Results We included 102 521 postmenopausal women enrolled in the Women’s Health Initiative between 1993 and 1998, and followed them through February 2017. During 1 876 205 person‐years of follow‐up, 25 976 deaths occurred. Comparing the highest with the lowest quintile, plant protein intake was inversely associated with all‐cause mortality (hazard ratio [HR], 0.91 [0.86, 0.96]), cardiovascular disease mortality (HR, 0.88 [0.79, 0.97]), and dementia mortality (HR, 0.79 [0.67, 0.94]). Among major protein sources, comparing the highest with the lowest quintile of consumption, processed red meat (HR, 1.06 [1.01, 1.10]) or eggs (HR, 1.14 [1.10, 1.19]) was associated with higher risk of all‐cause mortality. Unprocessed red meat (HR, 1.12 [1.02, 1.23]), eggs (HR, 1.24 [1.14, 1.34]), or dairy products (HR, 1.11 [1.02, 1.22]) was associated with higher risk of cardiovascular disease mortality. Egg consumption was associated with higher risk of cancer mortality (HR, 1.10 [1.02, 1.19]). Processed red meat consumption was associated with higher risk of dementia mortality (HR, 1.20 [1.05, 1.32]), while consumption of poultry (HR, 0.85 [0.75, 0.97]) or eggs (HR, 0.86 [0.75, 0.98]) was associated with lower risk of dementia mortality. In substitution analysis, substituting of animal protein with plant protein was associated with a lower risk of all‐cause mortality, cardiovascular disease mortality, and dementia mortality, and substitution of total red meat, eggs, or dairy products with nuts was associated with a lower risk of all‐cause mortality. Conclusions Different dietary protein sources have varying associations with all‐cause mortality, cardiovascular disease mortality, and dementia mortality. Our findings support the need for consideration of protein sources in future dietary guidelines.

scholarly journals Job Strain, Job Insecurity, and Incident Cardiovascular Disease in the Women’s Health Study: Results from a 10-Year Prospective Study

PLoS ONE ◽  
2012 ◽  
Vol 7 (7) ◽  
pp. e40512 ◽  
Author(s):  
Natalie Slopen ◽  
Robert J. Glynn ◽  
Julie E. Buring ◽  
Tené T. Lewis ◽  
David R. Williams ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Prospective Study ◽  
Women’S Health ◽  
Women's Health ◽  
Job Strain ◽  
Job Insecurity ◽  
Health Study ◽  
Study Results ◽  
Incident Cardiovascular Disease

scholarly journals A prospective study of low fasting glucose with cardiovascular disease events and all-cause mortality: The Women's Health Initiative

Metabolism ◽  
2017 ◽  
Vol 70 ◽  
pp. 116-124 ◽  
Author(s):  
Morgana Mongraw-Chaffin ◽  
Andrea Z. LaCroix ◽  
Dorothy D. Sears ◽  
Lorena Garcia ◽  
Lawrence S. Phillips ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Prospective Study ◽  
Women's Health ◽  
Fasting Glucose ◽  
Women's Health Initiative ◽  
Women’S Health Initiative ◽  
Health Initiative ◽  
All Cause Mortality ◽  
A Prospective Study ◽  
The Women’S Health Initiative

Prospective Study to Evaluate the Efficacy and Safety of Pitavastatin in Patients with Risk Factor of Cardiovascular Disease(PEACE Study)

2007 ◽  
Vol 37 (1) ◽  
pp. 16 ◽  
Author(s):  
Cheol-Ho Kim ◽  
Kwang-Il Kim ◽  
Jae-Hyung Kim ◽  
Jae-Eun Jun ◽  
Jong-Hwa Bae ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Risk Factor ◽  
Prospective Study ◽  
Efficacy And Safety ◽  
Peace Study
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