Chemical Composition Effect of Sol-Gel Derived Bioactive Glass Over Bioactivity Behavior

Author(s):  
L. A. Quintero ◽  
D. M. Escobar
2019 ◽  
Vol 801 ◽  
pp. 21-26
Author(s):  
Wei Fang ◽  
Bo Rui Huang ◽  
Tzu Hao Liu ◽  
Jhih An Chen ◽  
Ching Fen Chang ◽  
...  

Bioactive glass has high biocompatibility and bioactivity. With specific ion adding, it can show different advantages. Titanium ion can improve the mechanic strength, antibacterial ability of bioactive glass, and stability. In this study, bioactive glass with titanium ion doping by the sol-gel method via various reactive environments was fabricated successfully. The morphology was observed by scanning electron microscopy (SEM). The chemical composition was measured by energy dispersive X-ray spectrometer (EDS). By soaking in SBF, the bioactivity of samples had also been analyzed. The formula of bioglass has been optimized to make the better bioactivity.


2011 ◽  
Vol 26 (8) ◽  
pp. 869-873
Author(s):  
Xue HAN ◽  
Xiao-Feng CHEN ◽  
Yong-Chun MENG ◽  
Jia-An ZHOU ◽  
Cai LIN ◽  
...  

2020 ◽  
Vol 10 (7) ◽  
pp. 2595 ◽  
Author(s):  
Chih-Ling Huang ◽  
Wei Fang ◽  
Bo-Rui Huang ◽  
Yan-Hsiung Wang ◽  
Guo-Chung Dong ◽  
...  

Bioactive glass (BG) was made by the sol–gel method and doped with boron (B) to increase its bioactivity. Microstructures of BG and B-doped BG were observed by scanning electron microscopy, and phase identification was performed using an X-ray diffraction diffractometer. The ion concentrations released after soaking in simulated body fluid (SBF) for 1, 4, and 7 days were measured by inductively coupled plasma mass spectrometry, and the pH value of the SBF was measured after soaking samples to determine the variation in the environment. Brunauer–Emmett–Teller (BET) analysis was performed to further verify the characteristics of mesoporous structures. High performance liquid chromatography was used to evaluate the drug delivery ability of teicoplanin. Results demonstrated that B-doped BG performed significantly better than BG in parameters assessed by the BET analysis. B-doped BG has nanopores and more rough structures, which is advantageous for drug delivery as there are more porous structures available for drug adsorption. Moreover, B-doped BG was shown to be effective for keeping pH values stable and releasing B ions during soaking in SBF. The cumulative release of teicoplanin from BG and B-doped BG reached 20.09% and 3.17% on the first day, respectively. The drug release gradually slowed, reaching 29.43% and 4.83% after 7 days, respectively. The results demonstrate that the proposed bioactive glass has potential as a drug delivery system.


2016 ◽  
Vol 81 (1) ◽  
pp. 84-94 ◽  
Author(s):  
Anthony L. B. Maçon ◽  
Manon Jacquemin ◽  
Samuel J. Page ◽  
Siwei Li ◽  
Sergio Bertazzo ◽  
...  

2008 ◽  
Vol 396-398 ◽  
pp. 131-134 ◽  
Author(s):  
Ourania Menti Goudouri ◽  
Xanthippi Chatzistavrou ◽  
Eleana Kontonasaki ◽  
Nikolaos Kantiranis ◽  
Lambrini Papadopoulou ◽  
...  

Thermal treatment of bioactive glasses can affect their microstructure and thus their bioactivity. The aim of this study was the characterization of the thermally treated sol-gel-derived bioactive glass 58S at characteristic temperatures and the dependence of its bioactive behavior on the specific thermal treatment. The thermal behavior of the bioactive glass was studied by thermal analysis (TG/DTA). Fourier Transform Infrared Spectroscopy (FTIR) and X-ray Diffractometry (XRD) were used for the characterization of the bioactive glass. The bioactive behavior in Simulated Body Fluid (SBF) was examined by Scanning Electron Microscopy (SEM-EDS) and FTIR. The major crystal phases after thermal treatment were Calcium Silicates, Wollastonite and Pseudowollastonite, while all thermally treated samples developed apatite after 48 hours in SBF. A slight enhancement of bioactivity was observed for the samples heated at the temperature range 910-970oC.


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