Cell Commitment by Asymmetric Division and Immune System Involvement

2007 ◽  
pp. 179-204 ◽  
Author(s):  
Antonin Bukovsky
Keyword(s):  
Immune System ◽  
Asymmetric Division ◽  
System Involvement ◽  
Cell Commitment

scholarly journals The Immune System, Involvement in Neurodegenerative Diseases, Ageing and Cancer

2005 ◽  
Vol 4 (4) ◽  
pp. 349-352 ◽  
Author(s):  
Evan Booy ◽  
Dina Johar ◽  
Kamran Kadkhoda ◽  
Graham Bay ◽  
Marek Los
Keyword(s):  
Immune System ◽  
Neurodegenerative Diseases ◽  
System Involvement

scholarly journals Immune system involvement in specific pain conditions

2017 ◽  
Vol 13 ◽  
pp. 174480691772455 ◽  
Author(s):  
Stacie K Totsch ◽  
Robert E Sorge
Keyword(s):  
Immune System ◽  
System Involvement

scholarly journals Immunohistochemical Evidence of Skin Immune System Involvement in Vulvar Lichen sclerosus et atrophicus

Dermatology ◽  
1991 ◽  
Vol 182 (1) ◽  
pp. 18-22 ◽  
Author(s):  
P. Carli ◽  
A. Cattaneo ◽  
N. Pimpinelli ◽  
A. Cozza ◽  
G. Bracco ◽  
...  
Keyword(s):  
Immune System ◽  
Lichen Sclerosus ◽  
Lichen Sclerosus Et Atrophicus ◽  
System Involvement ◽  
Skin Immune System ◽  
Immunohistochemical Evidence ◽  
Vulvar Lichen Sclerosus

Evidence for Immune System Involvement in Reflex Sympathetic Dystrophy

1998 ◽  
Vol 23 (2) ◽  
pp. 147-150 ◽  
Author(s):  
J. S. CALDER ◽  
I. HOLTEN ◽  
R. M. R. McALLISTER
Keyword(s):  
Immune System ◽  
Langerhans Cells ◽  
Reflex Sympathetic Dystrophy ◽  
Incidental Finding ◽  
System Involvement ◽  
Significant Pain ◽  
Skin Biopsies

Skin biopsies from patients with reflex sympathetic dystrophy were immunostained using a variety of antisera. An incidental finding with S100 staining was the presence of numerous Langerhans cells in the epidermis. All patients had significant pain at the time of biopsy, and all had symptoms refractory to treatment. The potential implications of this finding are discussed.

ASSESSMENT OF IMMUNE SYSTEM INVOLVEMENT IN TOURETTE SYNDROME

1999 ◽  
Vol 58 (5) ◽  
pp. 522
Author(s):  
A. D. Levine ◽  
B. H. Liwnicz ◽  
S. M. Roddy ◽  
O. R. Fagoaga ◽  
S. L. Nehlsen-Cannarella
Keyword(s):  
Immune System ◽  
Tourette Syndrome ◽  
System Involvement

Allergic contact dermatitis: Immune system involvement and distinctive clinical cases

2011 ◽  
Vol 39 (6) ◽  
pp. 374-377 ◽  
Author(s):  
S. Imbesi ◽  
P.L. Minciullo ◽  
S. Isola ◽  
S. Gangemi
Keyword(s):  
Immune System ◽  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
System Involvement ◽  
Allergic Contact ◽  
Clinical Cases

scholarly journals B and T cells are not required for the viable motheaten phenotype.

1996 ◽  
Vol 183 (2) ◽  
pp. 371-380 ◽  
Author(s):  
C C Yu ◽  
H W Tsui ◽  
B Y Ngan ◽  
M J Shulman ◽  
G E Wu ◽  
...  
Keyword(s):  
T Cells ◽  
Immune System ◽  
Autoimmune Disease ◽  
Protein Phosphorylation ◽  
Protein Function ◽  
Double Mutant ◽  
Cell Types ◽  
System Involvement ◽  
Major Mechanism ◽  
Rag 1

Hematopoietic cell phosphatase (HCP), encoded by the hcph gene, (also called PTP1C, SHP, SH-PTP1, and PTPN6) is deficient in motheaten (me/me), and the allelic viable motheaten (me(v)/me(v)) mice. Since HCP is expressed in many cell types and protein phosphorylation is a major mechanism of regulating protein function, it is not surprising that the motheaten phenotype is pleiotropic. It is commonly thought that immune system involvement causes this disease. If so, the motheaten disease ought to be alleviated when the recombination activation gene-1 (RAG-1) is disrupted because there will be no V(D)J rearrangement and thus impaired development of B and T cells. We bred homozygous, double-mutant me(v)/me(v) x RAG 1 -/- mice and found that, in fact, inflamed paws, and splenomegaly with elevated myelopoiesis. Thus, except for autoantibodies, the motheaten phenotype does not depend on the presence of B and T cells. This observation cautions the use of motheaten mice as a model of autoimmune disease.

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