Research and Development (R&D) Continuity of Biotech Start-ups in Financial Crisis

2015 ◽  
pp. 203-221
Author(s):  
Takao Fujiwara
Keyword(s):  
Financial Crisis ◽  
Research And Development ◽  
Start Ups

New Transcatheter Mitral Valve Treatment

2011 ◽  
Vol 6 (1) ◽  
pp. 62
Author(s):  
Raquel del Valle-Fernández ◽  
Carlos E Ruiz ◽  
◽  
Keyword(s):  
Mitral Valve ◽  
Financial Crisis ◽  
Mitral Regurgitation ◽  
Research And Development ◽  
Therapeutic Option ◽  
Percutaneous Treatment ◽  
Severe Mitral Regurgitation ◽  
Proof Of Concept ◽  
Safety And Efficacy

Percutaneous treatment of severe mitral regurgitation is a very interesting therapeutic option for those patients considered not to be suitable candidates for surgery. Different technologies have already demonstrated proof-of-concept, and one of these devices (the Mitraclip device) has already obtained the Conformité Europeéne mark. However, demonstrating safety and efficacy for most of these technologies is being harder than anticipated. Recently, research and development has become more compromised due to the financial crisis. This paper reviews the venues that are currently under evaluation.

scholarly journals Innovation and Entrepreneurship in a Space-time Framework Based on the Case of Poland

2019 ◽  
Vol 15 (2) ◽  
pp. 24-39
Author(s):  
Aleksandra Gaweł
Keyword(s):  
Research And Development ◽  
Explanatory Power ◽  
Regression Function ◽  
Regression Analyses ◽  
Initial Stage ◽  
Start Ups ◽  
The Relationship ◽  
Innovation Impact ◽  
Yearly Data ◽  
Innovation And Entrepreneurship

Although innovation and entrepreneurship have been subjects of researchers’ interests for years, nevertheless both the concepts and the relationships between them remain controversial. Since different indices are accepted for the measurement of these categories, the question is whether the relationship between them depends on the choice of measures. The aim of the paper is to indicate the innovation impact on the entrepreneurial process with regard to different measures of these concepts. The research was conducted with the use of regression analyses as a method and yearly data for Polish regions in the period 2003–2018. At the initial stage of the research as many measures of innovation and entrepreneurship as possible were introduced into the estimation of regression function parameters. Statistically insignificant variables were deleted at later stages of research. This research confirms that innovativeness and entrepreneurship are broad concepts and the relationship between them depends on the choice of measures. Saturation with enterprises and saturation with start-ups seem to be more sensitive to innovation than other measures of entrepreneurship. Innovation seen as input, measured by spending on research and development (R&D) has a bigger influence on entrepreneurship than the output innovation measured by revenues from innovative activities. Considering a relatively low level of explanatory power of innovations, it seems they are not the only factor influencing entrepreneurship.

Three Views of a Train Wreck

2016 ◽  
Author(s):  
Michael Kinch
Keyword(s):  
Public Health ◽  
Research And Development ◽  
Venture Capital ◽  
Food Chain ◽  
Early Stage ◽  
Health Benefits ◽  
Federal Spending ◽  
Moore’S Law ◽  
Government Grants ◽  
Start Ups

Despite and arguably because of the enormous public health benefits arising from the introduction of new medicines, the industry is in the midst of crisis. We detail in this chapter the decline in research and development efficiency, which has been termed “Eroom's Law,” a playful inversion of the bettern known Moore's Law of Computing. An explanation of declining efficiency follows as is a brief summary of some remedies taken by many biopharmaceutical entities, including the abandonment of therapeutics targeting particularly difficult indications such as Alzheimer's disease and antibiotics. We also convey how the industry has developed into a sort of food chain, with smaller companies and government grants supporting the earliest stages of research, which are then acquired by medium-sized companies, which in turn are consolidated into large companies. This food chain is fundamentally in doubt based on shrinking Federal spending on research combined with a decline in venture capital support for early-stage start-ups.

scholarly journals Financing structure of portuguese start-ups

2017 ◽  
Vol 7 (4-1) ◽  
pp. 135-147
Author(s):  
Liliana Raquel R. Silva ◽  
Luís M. P. Gomes
Keyword(s):  
Data Analysis ◽  
Panel Data ◽  
Financial Crisis ◽  
Panel Data Analysis ◽  
Financial Structure ◽  
Cross Sectional ◽  
Legal Form ◽  
Financing Structure ◽  
Creative Solutions ◽  
Start Ups

The context where the companies operate has become more challenging given the binomial competitiveness and financial crisis. Market imbalances are an opportunity to explore creative solutions that characterize Start-Ups’ profiles. However, its innovative character carries risks that determine major funding difficulties. This way this article aims to investigate the influence of a set of variables in the composition of the financial structure of Portuguese Start-Ups. The methodology used is based on a cross-sectional data, integrating multivariate regressions (Logit, Tobit, and OLS), enriched by panel data analysis. The results show that company’s size, assets structure and legal form are statistically relevant.

Creativity And Benchmarking Influence On Research, Production And Marketing In Romanian Organizations

2014 ◽  
Vol 1 (1) ◽  
pp. 505-508
Author(s):  
Gina-Maria Moraru
Keyword(s):  
Financial Crisis ◽  
Research And Development ◽  
Organizational Performance ◽  
University Management ◽  
Industrial Environment ◽  
Research Production ◽  
Industrial Organizations ◽  
Organizational Functions

AbstractThe paper is a small part of a research made for identify if benchmarking is or can be used in creativity management in Romanian organizations, in order to combat the effects of the economic-financial crisis and to increase organizational performance. Using questionnaires, the author collected data from the academic and industrial environment. The paper related the creativity and benchmarking influence on three of the organizational functions: research and development, production and marketing. First, it presents an original synthesis about the theory in this field. Second, it presents the results of a research performed on three categories of respondents: PhD candidates in management, university management professors and managers from industrial organizations. Finally, it suggested some modalities for an efficient use of creativity and benchmarking in Romanian organizations.

scholarly journals Creating Financial Statements For Start-Ups

2020 ◽  
Vol 8 (1) ◽  
pp. 104-114
Author(s):  
Tanneru Anusha ◽  
Nedunuri Sushma ◽  
M B Sai Rohit ◽  
A Akhil
Keyword(s):  
Research And Development ◽  
Positive Association ◽  
Financial Statements ◽  
Financial Statement ◽  
High Tech ◽  
Stages Of Development ◽  
Association Frequency ◽  
Intangible Investments ◽  
Start Ups ◽  
Funding Level

This paper represents the sample of entrepreneurs who are in the process of starting a business. At investigates the determinants of financial projections and statements in start-ups. The predictions information in economics is consistent. There is a positive association frequency of financial statement preparation concerning the use of outside funding, level competition, and venture scale. There are alternative influences and suggestions that benefit in reducing competition and uncertainty in fundamental variations to prepare financial statements. For instance, cash statements are more important for start-ups, and frequency varies among different financial statements with products in earlier stages of development and with greater competition. In contrast to this financial statements projections and regular forecasts of sales by start-ups are positively associated with the importance of intangible investments such as parents, research, and development. The start-ups in high –tech industries are used for projections. 

Accelerating Financial Innovation Through RegTech

2021 ◽  
pp. 61-79
Author(s):  
Shilpa Narang
Keyword(s):  
Financial Crisis ◽  
Financial Institutions ◽  
Financial Innovation ◽  
Regulatory System ◽  
Regulatory Compliance ◽  
Technological Knowledge ◽  
Financial Service ◽  
Global Banking ◽  
The World ◽  
Start Ups

The buzz word ‘RegTech' is on the rise. A financial service regulation has inflated at an astounding rate since the financial crisis and, therefore, has the price tag of regulatory compliance. Many start-ups have begun to apply digital technological knowledge including APIs, AI, RPAs, and many more to these immediate, numerous, and burdensome tasks to meet the terms and regulations, hence the emergence of RegTech. This study examines the implications for financial institutions and regulation particularly when technology poses a confront to the global banking and regulatory system. It attempts to examine the characteristics and applications of RegTech in the world of regulatory compliance. It also illustrates a model to define the transformation of present workload to proposed workload of regulatory compliance with an application of RegTech.

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