Selective retests in automated perimetry: an experimental study for the evaluation of the effect of the regression towards the mean

Author(s):  
Charlotte Rutishauser ◽  
J. Flammer
2021 ◽  
Vol 108 ◽  
pp. 106377
Author(s):  
Mohammed Faheem ◽  
Aqib Khan ◽  
Rakesh Kumar ◽  
Sher Afghan Khan ◽  
Waqar Asrar ◽  
...  

2021 ◽  
Vol 74 (6) ◽  
Author(s):  
Cristina Furtado Volcov ◽  
Eliana Moreira Pinheiro ◽  
Miriam Harumi Tsunemi ◽  
Fernanda Gaspar do Amaral ◽  
Ariane Ferreira Machado Avelar ◽  
...  

ABSTRACT Objectives: to compare the parameters of the activity/rest cycle of early postpartum breastfeeding women under a controlled and uncontrolled long wavelength ray light regimen. Methods: quasi-experimental study with breastfeeding women and their babies during postnatal rooming-in, São Paulo, Brazil. Participants were allocated to either an experimental (intervention) or a comparison group. The intervention involved exposure of the woman in a controlled room with artificial long wavelength ray light at night. Each woman’s level of 6-sulfatoxymelatonin at 24 hours and activity/rest times was analyzed. Results: the mean activity/rest times of women in the experimental and comparison groups were similar. The mean percentages of total load of 6-sulfatoxymelatonin during the day and night were similar (p=0.09). At 24 hours, the experimental group presented a significantly lower mean percentage of total load compared to the comparison group (p=0.04). Conclusions: women who stayed in the room with long-wavelength artificial light showed no difference in activity/rest and 6-sulfatoxymelatonin levels in the early postpartum period.


2020 ◽  
Vol 12 (1) ◽  
pp. 115-121
Author(s):  
Andi Asrina ◽  
Arsyad Aryadi ◽  
Nilawati Andi

This study aims to determine the comparison of prostaglandin and endorphin levels in adolescents with primary dysmenorrhea with and without warm (37-40oC) and cold (18-20oC) hydrotherapy. This quasi-experimental study with a post-test only controls group design was carried out in Islamic Boarding Schools with a sample of 36 young girls divided into 3 groups: 12 teens given warm hydrotherapy, 12 teens given cold hydrotherapy and 12 teens not given intervention (control). Blood plasma is taken after an intervention is given on the first day of menstruation. Examination of prostaglandin and endorphins levels using the enzyme-linked immunosorbent assay (ELISA) kit method. After cold hydrotherapy, the mean levels of prostaglandins in the cold hydrotherapy group were twice higher (569 pg/ml) compared to controls (394 pg/ml). The mean prostaglandin level in the warm hydrotherapy group also showed an increase prostaglandin (437 pg/ml) compared to the control (394 pg/ml). In addition to increasing levels of prostaglandins, increased levels of endorphins also occurred in the group given warm hydrotherapy (154 pg/ml) and the group was given cold hydrotherapy (187 pg/ml) compared to the control (119 pg/ml) p = 0.001. The conclusion in this study is that warm and cold hydrotherapy can increase levels of prostaglandins and endorphins in adolescents with primary dysmenorrhea. However, cold hydrotherapy increases endorphin levels higher than warm hydrotherapy. Key words: Prostaglandin, Endorphin, Hydrotherapy, Primary Dismenorrhea.


2021 ◽  
Vol 248 ◽  
pp. 04002
Author(s):  
Alexander Metel ◽  
Enver Mustafaev ◽  
Yury Melnik ◽  
Khaled Hamdy

We present results of theoretical and experimental study of collisional relaxation of fast electrons energy in gas. The dependence on the gas pressure p and electron energy ε of the mean pass Λ of fast electrons injected into a gas being sufficient to spend on ionization all their initial energy ε has been calculated. It was found that Λ is directly proportional to ε2 and inversely proportional to the gas pressure. To sustain glow discharge with electrostatic confinement of fast electrons, Λ should be less than the mean way to the anode of emitted by the cathode electrons.


Author(s):  
Cailey L. Nichols ◽  
Thomas J. Doherty ◽  
James Schumacher ◽  
Philip D. Jones ◽  
Xiaocun Sun

Abstract OBJECTIVE To determine whether palmar digital nerve (PDN) blockade in horses with a combination of dexmedetomidine and mepivacaine would block the response to mechanical force applied to the digit longer than would anesthetizing these nerves with mepivacaine alone or dexmedetomidine alone. ANIMALS 8 mares with no signs of lameness. PROCEDURES In a randomized, crossover, blinded, experimental study, both PDNs of the same forelimb of each horse were anesthetized by perineural injection with either 30 mg mepivacaine alone, 250 µg of dexmedetomidine alone, or 30 mg mepivacaine combined with 250 µg of dexmedetomidine. Each horse received each treatment, and treatments were administered ≥ 2 weeks apart. The mechanical nociceptive threshold was measured at a region between the heel bulbs with the use of a digital force gauge before (baseline) and at 15-minute intervals after treatment. RESULTS The mean duration of sensory blockade of the digit was 2-fold longer when a combination of mepivacaine and dexmedetomidine was administered (371 minutes), compared with when mepivacaine alone was administered (186 minutes). Treatment with dexmedetomidine alone did not change the mechanical nociceptive threshold substantially from baseline and resulted in no clinical signs of sedation. CLINICAL RELEVANCE Results indicated that relief from digital pain provided by perineural treatment with mepivacaine for PDN blockade can be extended by adding dexmedetomidine to the injectate.


1993 ◽  
Vol 16 (2) ◽  
pp. 86-90 ◽  
Author(s):  
S. Stamatelopoulos ◽  
N. Zakopoulos ◽  
N. Saridakis ◽  
S. Stefanou ◽  
A. Adractas ◽  
...  

This experimental study compares the effect of catecholamine infusion to the effect of intraaortic counterpulsation (IABP) while initiating intraventricular balloon pumping (IVBP) in the fibrillating heart. In 12 dogs IVBP started immediately after the induction of ventricular fibrillation. Intravenous adrenaline or noradrenaline (at a progressively increasing infusion rate until the systolic aortic blood pressure was 120 mm Hg) was interchanged with IABP. The systolic aortic pressure, the aotic flow and the mean left atrial pressure were, respectively, 120.4 ± 0.5 mm Hg, 42 ± 4 mlkg-1min-1 and 18.7 ± 1.2 mm Hg (x ± SEM) ten min after initiating catecholamine infusion and 97 ± 5 mm Hg (with a 131 ± 4 mm Hg diastolic wave), 69.6 ± 4 mlkg-1min-1 and 16 ± 1.5 mm Hg ten min after initiating IABP. The difference in aortic flow was significant (p<0.001). The results indicate that a better aortic flow may be obtained by combining IVBP and IABP than IVBP and vasoconstrictive agents in the fibrillating heart. If IVBP, IABP and catecholamines are combined, both AF and AP may increase.


1985 ◽  
Vol 31 (4) ◽  
pp. 581-584 ◽  
Author(s):  
P G Reeves ◽  
B L O'Dell

Abstract The activity in serum of zinc-dependent angiotensin converting enzyme (ACE), is measured to aid in diagnosis and monitor treatment of certain diseases. This report shows the effect of dietary zinc deprivation on ACE activity in the serum of rats. The mean (and SE) of the zinc concentration (mumol/L) in serum was 3.5 (0.3) in rats deprived of dietary zinc for four days, 16.3 (0.2) in control rats, and 19.8 (0.9) in rats deprived of zinc for four days, then repleted with zinc for 12 h. The respective mean (and SE) of ACE activities (nmol/mL per min) in serum were 390 (15), 543 (13), and 545 (20). Serum ACE activity was restored also by adding zinc to the assay mixture in vitro. The Vmax for ACE was 1.4 times greater when serum was diluted 40-fold as compared with twofold dilution. There was a small effect on the Km for the substrate, but the Km for zinc was decreased by 22-fold when serum was diluted 40-fold. The Vmax under these conditions was decreased by only 9%.


Author(s):  
R S Birch ◽  
N Jones

The design and selection of transducers is an important consideration for the measurement of impact loads. This paper examines a load-measuring transducer based on a non-contact laser Doppler principle. An experimental study assesses the deformations and velocities obtained using a laser Doppler velocimeter and compares the mean and peak loads with those recorded by an accelerometer and a load cell. The paper concludes that this device is a valuable tool in the structural impact research field.


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