Statistical Treatment of Model Output

Author(s):  
M. Deque
Metrologiya ◽  
2020 ◽  
pp. 16-24
Author(s):  
Alexandr D. Chikmarev

A single program has been developed to ensure that the final result of the data processing of the measurement calibration protocol is obtained under normal conditions. The calibration result contains a calibration function or a correction function in the form of a continuous sedate series and a calibration chart based on typical additive error probabilities. Solved the problem of the statistical treatment of the calibration protocol measuring in normal conditions within a single program “MMI–calibration 3.0” that includes identification of the calibration function in a continuous power series of indications of a measuring instrument and chart calibration. An example of solving the problem of calibration of the thermometer by the working standard of the 3rd grade with the help of the “MMI-calibration 3.0” program.


1986 ◽  
Vol 84 ◽  
Author(s):  
M.D. Merz ◽  
F. Gerber ◽  
R. Wang

AbstractThe Materials Characterization Center (MCC) at Pacific Northwest Lab- oratory is performing three kinds of corrosion tests for the Basalt Waste Isolation Project (BWIP) to establish the interlaboratory reproducibility and uncertainty of corrosion rates of container materials for high-level nuclear waste. The three types of corrosion tests were selected to address two distinct conditions that are expected in a repository constructed in basalt. An air/steam test is designed to address corrosion during the operational period and static pressure vessel and flowby tests are designed to address corrosion under conditions that bound the condi ring the post-closure period of the repository.The results of tests at reference testing conditions, which were defined to facilitate interlaboratory comparison of data, are presented. Data are reported for the BWIP/MCC-105.5 Air/Steam Test, BWIP/MCC-105.1 Static Pressure Vessel, and BWIP/MC-105.4 Flowby Test. In those cases where data are available from a second laboratory, a statistical analysis of interlaboratory results is reported and expected confidence intervals for mean corrosion rates are given. Other statistical treatment of data include analyses of the effects of vessel-to-vessel variations, test capsule variations for the flowby test, and oven-to-oven variations for air/steam tests.


1996 ◽  
Vol 33 (2) ◽  
pp. 79-90 ◽  
Author(s):  
Jian Hua Lei ◽  
Wolfgang Schilling

Physically-based urban rainfall-runoff models are mostly applied without parameter calibration. Given some preliminary estimates of the uncertainty of the model parameters the associated model output uncertainty can be calculated. Monte-Carlo simulation followed by multi-linear regression is used for this analysis. The calculated model output uncertainty can be compared to the uncertainty estimated by comparing model output and observed data. Based on this comparison systematic or spurious errors can be detected in the observation data, the validity of the model structure can be confirmed, and the most sensitive parameters can be identified. If the calculated model output uncertainty is unacceptably large the most sensitive parameters should be calibrated to reduce the uncertainty. Observation data for which systematic and/or spurious errors have been detected should be discarded from the calibration data. This procedure is referred to as preliminary uncertainty analysis; it is illustrated with an example. The HYSTEM program is applied to predict the runoff volume from an experimental catchment with a total area of 68 ha and an impervious area of 20 ha. Based on the preliminary uncertainty analysis, for 7 of 10 events the measured runoff volume is within the calculated uncertainty range, i.e. less than or equal to the calculated model predictive uncertainty. The remaining 3 events include most likely systematic or spurious errors in the observation data (either in the rainfall or the runoff measurements). These events are then discarded from further analysis. After calibrating the model the predictive uncertainty of the model is estimated.


1990 ◽  
Vol 55 (6) ◽  
pp. 1427-1434 ◽  
Author(s):  
František Pavelčík ◽  
Eva Luptáková

The conformational surface of the Co(en) chelate ring was studied by the method of structural correlation. The reduction of dimensionality of the conformation problem was achieved by employing the pseudorotation concept. The empirical potential surface was obtained by statistical treatment of 743 independent conformations from the Cambridge Structural Database. The theoretical potential surface was obtained by molecular mechanics. The minimal-energy conformation is gauche with the Co atom on the two-fold axis. Conformational flexibility also includes an envelope conformation with the N atom bent out of the plane. The transition between the mirror-image symmetrical conformations can occur by a pseudorotation pathway and is accompanied by increased planarity of the ring. The transition state is an envelope conformation with an out-plane Co atom.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Fernando do Pazo-Oubiña ◽  
Bartomeu Alorda-Ladaria ◽  
Ana Gomez-Lobon ◽  
Bàrbara Boyeras-Vallespir ◽  
María Margalida Santandreu-Estelrich ◽  
...  

AbstractMore thermolabile drugs are becoming available, and in most cases, these medications are dispensed to ambulatory patients. However, there is no regulation once medications are dispensed to patients and little is known with regard to what happens during transport and home storage. Previous studies suggest that these drugs are improperly stored. The present study was designed to determine the storage conditions of thermolabile drugs once they are dispensed to the patient in the Hospital Pharmacy Department. This is a prospective observational study to assess the temperature profile of 7 thermolabile drugs once they are dispensed to ambulatory patients at a tertiary care hospital. A data logger was added to the medication packaging. Temperature was considered inappropriate if one of the following circumstances were met: any temperature record less than or equal to 0 °C or over 25 °C; temperatures between 0–2 or 8–25 °C for a continuous period over 30 min. The time series of temperature measurements obtained from each data logger were analyzed as statistically independent variables. The data shown did not undergo any statistical treatment and must be considered directly related to thermal measurements. One hundred and fourteen patients were included and 107 patients were available for the analysis. On the whole, a mean of 50.6 days (SD 18.3) were measured and the mean temperature was 6.88 °C (SD 2.93). Three data loggers (2.8%) maintained all the measurements between 2 and 8 °C with less than 3 continuous data (< 30 min) out of this range but no data over 25 °C or below or equal to 0 °C. 28 (26.2%) data loggers had at least one measurement below zero, 1 data logger had a measurement greater than 25 °C and 75 (70.1%) were between 0 and 2 °C and/or between 8 and 25 °C for more than 30 min. In conclusion, once dispensed to patients, most thermolabile drugs are improperly stored. Future studies should focus on clinical consequences and possible solutions.


2020 ◽  
Vol 2020 (7) ◽  
Author(s):  
Yuval Grossman ◽  
Emilie Passemar ◽  
Stefan Schacht

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