Opportunities for Lighter Weight and Lower Total Cost Component Manufacturing

Author(s):  
Jim Williams ◽  
Brian Post ◽  
Lonnie J. Love ◽  
Craig Blue
2020 ◽  
Author(s):  
jefferson buendia ◽  
Ranniery Acuña-Cordero

Abstract BackgroundPharmacological treatment for bronchiolitis is primarily supportive because bronchodilators, steroids, and antibiotics, show little benefit. Clinical studies have suggested that nebulized 3% hypertonic solution is useful for infants with bronchiolitis. This study aims to evaluate the cost-effectiveness of the HS inhalations in infant bronchiolitis in a tropical country Methods Decision tree analysis was used to calculate the expected costs and QALYs. All cost and use of resources were collected directly from medical invoices of 193 patient hospitalized with diagnosis of bronchiolitis in tertiary centers, of Rionegro, Colombia. The utility values applied to QALYs calculations were collected from the literature. The economic analysis was carried out from a societal perspective.ResultsThe model showed that nebulized 3% hypertonic solution, was associated with lower total cost than controls (US $200vs US $240 average cost per patient), and higher QALYs ( 0.92 vs 0.91 average per patient); showing dominance. A position of dominance negates the need to calculate an incremental cost-effectiveness ratio.Conclusion The nebulized 3% hypertonic solution was cost-effective in the inpatient treatment of infant bronchiolitis. Our study provides evidence that should be used by decision-makers to improve clinical practice guidelines and should be replicated to validate their results in other tropical countries.


2021 ◽  
Vol 9 (4) ◽  
pp. 553
Author(s):  
Arif Ardha Kenamon ◽  
Fembriarti Erry Prasmatiwi ◽  
Lina Marlina

The purposes of this research are analyze technical efficiency, factors that affecting technical efficiency, cost structure, break even point, and income of inbred rice seed breeding. Furthermore, this research uses a survey method. The location of the research is chosen purposively in Bumi Ratu Nuban Subdistrict Central Lampung Regency as consideration that there are active and sustainable groups of farmer on inbred rice seed breeding. It should be noted that the number of respondent is 44 farmers which are collected randomly. Additionally, this research was conducted since August-September 2019. The analytical method uses frontier production function, multiple linear regression model, independent sample t-test, cost structure, break even point, and income analysis. The result shows that the level of technical efficiency is quiet efficient by 78.13 percent. Factors that significantly affecting technical efficiency are farming cost, revenue, capital, and land ownership status. The biggest cost component of cost structure for total cost is labor cost by 46.29 percent. Finally, the inbred rice seed breeding is profitable, because BEP value is smaller than revenue, production, and price that obtained by farmers and R/C for total cost is more than 1.Key words: cost structure, inbred rice seed breeding, income, technical efficiency


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Jefferson Antonio Buendía ◽  
Ranniery Acuña-Cordero

Abstract Background Pharmacological treatment for bronchiolitis is primarily supportive because bronchodilators, steroids, and antibiotics, show little benefit. Clinical studies have suggested that nebulized 3% hypertonic solution is useful for infants with bronchiolitis. This study aims to evaluate the cost-effectiveness of the HS inhalations in infant bronchiolitis in a tropical country. Methods Decision tree analysis was used to calculate the expected costs and QALYs. All cost and use of resources were collected directly from medical invoices of 193 patient hospitalized with diagnosis of bronchiolitis in tertiary centers, of Rionegro, Colombia. The utility values applied to QALYs calculations were collected from the literature. The economic analysis was carried out from a societal perspective. Results The model showed that nebulized 3% hypertonic solution, was associated with lower total cost than controls (US $200vs US $240 average cost per patient), and higher QALYs (0.92 vs 0.91 average per patient); showing dominance. A position of dominance negates the need to calculate an incremental cost-effectiveness ratio. Conclusion The nebulized 3% hypertonic solution was cost-effective in the inpatient treatment of infant bronchiolitis. Our study provides evidence that should be used by decision-makers to improve clinical practice guidelines and should be replicated to validate their results in other tropical countries.


2018 ◽  
Vol 42 (5) ◽  
Author(s):  
Ana Paula Almeida Ferraz ◽  
Gustavo Ventorim

ABSTRACT The kraft pulp of Eucalyptus spp. is relatively easy to be bleached. Therefore, studies have been carried out to reduce the number of stages of bleaching in the plant and minimize process costs. The present work aimed to evaluate the use of two short bleaching sequences in the physico-mechanical properties of cellulosic pulp as well as to compare these values to the ones obtained by usual bleaching sequences. The four bleaching sequences were ECF (elemental chlorine free), D0(E+P)D1P, AHTD0(E+P)D1P, and AHTDP and AHTD (PO). For each bleaching sequence the brightness, brightness reversion and total cost of reagents were evaluated. Physical and mechanical analyses were performed according to the methodologies of the Technical Association of the Pulp and Paper Industry (TAPPI, 2002). The AHTD (PO) sequence showed higher brightness, less brightness reversion, lower total cost and better smoothness compared to the reference sequences. However, it had a lower tear index and a lower compression index. The AHTDP sequence did not reach target brightness, however, it presented brightness reversion and lower total cost than the reference sequences. The AHTDP sequences showed high compression and smoothness, but presented a low compression index.


1992 ◽  
Vol 78 (6) ◽  
pp. 359-362 ◽  
Author(s):  
Stefano Capri ◽  
Edoardo Majno ◽  
Maurizio Mauri

The cost of the first hospital stay for operable breast cancer was deducted by analysing a random sample of 100 admissions to the National Institute of Cancer during the period January-December 1989. The aims of the study were: (1) to describe and calculate the cost component of the stay; (2) to analyse whether any procedure, service rended or stage of the pathology might explain differences in the total costs of the stay; and (3) to acquire a better knowledge of the organizational aspects to be improved. With an average length of stay of 14.1 days, the overall total cost observed was 4.9 million lira (US $ 3.800, 1989 US dollars). A significant correlation between total cost and duration of stay was found (R2 = 0.982), while no or very little correlation was found between cost and the anatomical extent of disease (TNM stage) and different cost items (laboratory, imaging tests, operating room, etc.). Two homogeneous groups of cases were found: patients with quadrantectomy and patients with mastectomy. The cost of the latter was 40% greater than that of the former (P < 0.001) with a length of stay 52% longer (p < 0.001). This study does not concern the costs immediately following the stay, which namely are higher for the quadrantectomy because the radiotherapy outpatient procedures. Attention should be paid to reducing the length of stay, keeping waiting time for organizational procedures to a minimum during the stay.


Author(s):  
Thuan Thanh Nguyen ◽  
Van-Duc Phan ◽  
Bach Hoang Dinh ◽  
Tan Minh Phan ◽  
Thang Trung Nguyen

In this paper, Cuckoo search algorithm (CSA) is suggested for determining optimal operation parameters of the combined wind turbine and hydrothermal system (CWHTS) in order to minimize total fuel cost of all operating thermal power plants while all constraints of plants and system are exactly satisfied. In addition to CSA, Particle swarm optimization (PSO), PSO with constriction factor and inertia weight factor (FCIWPSO) and Social Ski-Driver (SSD) are also implemented for comparisons. The CWHTS is optimally scheduled over twenty-four one-hour interval and total cost of producing power energy is employed for comparison. Via numerical results and graphical results, it indicates CSA can reach much better results than other ones in terms of lower total cost, higher success rate and faster search process. Consequently, the conclusion is confirmed that CSA is a very efficient method for the problem of determining optimal operation parameters of CWHTS.


Sign in / Sign up

Export Citation Format

Share Document