BGRIMM Pneumatic Mechanical Agitation Flotation Machine

2021 ◽  
pp. 263-316
Author(s):  
Zhengchang Shen
Keyword(s):  
Mechanical Agitation ◽  
Flotation Machine

Research on Vibration Characteristic of Flotation Machine Lower Shaft

2014 ◽  
Vol 552 ◽  
pp. 29-32
Author(s):  
Feng Wu ◽  
Mao He Lai ◽  
Yue Yu
Keyword(s):  
Wall Thickness ◽  
Element Model ◽  
Practical Significance ◽  
Vibration Characteristic ◽  
Practical Application ◽  
Mechanical Agitation ◽  
Flotation Machine ◽  
Hollow Shaft ◽  
The Difference ◽  
Shaft Wall

According to the lower shaft structure feature of a pneumatic and mechanical agitation flotation machine in the practical application, a finite element model is established on the basis of modality analytical theory of vibration structure. Through analyzing the modality characteristics of the lower shaft, the vibration mode of lower shaft is obtained. Moreover, through analyzing the modal characteristics of the lower shaft in condition of different impellers material and lower hollow shaft wall thickness, the conclusion is obtained that more lighter the impeller’ material is, more great the difference between natural frequencies and vibration excitation frequencies is. Another conclusion is that the lower shaft still do not resonate when the wall thickness of lower shaft thin appropriately. The conclusions of this paper have great theoretical and practical significance of further optimization of the flotation machine lower shaft structure.

scholarly journals Enhanced Photocatalytic Activity of CuWO4 Doped TiO2 Photocatalyst Towards Carbamazepine Removal under UV Irradiation

Separations ◽  
2021 ◽  
Vol 8 (3) ◽  
pp. 25
Author(s):  
Chukwuka Bethel Anucha ◽  
Ilknur Altin ◽  
Emin Bacaksız ◽  
Tayfur Kucukomeroglu ◽  
Masho Hilawie Belay ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Photocatalytic Activity ◽  
Photoelectron Spectroscopy ◽  
Diffuse Reflectance Spectroscopy ◽  
Sol Gel ◽  
Pure Tio2 ◽  
Component Part ◽  
Energy Yield ◽  
Mechanical Agitation ◽  
X Ray

Abatement of contaminants of emerging concerns (CECs) in water sources has been widely studied employing TiO2 based heterogeneous photocatalysis. However, low quantum energy yield among other limitations of titania has led to its modification with other semiconductor materials for improved photocatalytic activity. In this work, a 0.05 wt.% CuWO4 over TiO2 was prepared as a powder composite. Each component part synthesized via the sol-gel method for TiO2, and CuWO4 by co-precipitation assisted hydrothermal method from precursor salts, underwent gentle mechanical agitation. Homogenization of the nanopowder precursors was performed by zirconia ball milling for 2 h. The final material was obtained after annealing at 500 °C for 3.5 h. Structural and morphological characterization of the synthesized material has been achieved employing X-ray diffraction (XRD), Fourier transform infra-red (FTIR) spectroscopy, Brunauer–Emmett–Teller (BET) N2 adsorption–desorption analysis, Scanning electron microscopy-coupled Energy dispersive X-ray spectroscopy (SEM-EDS), Transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), and UV-Vis diffuse reflectance spectroscopy (UV-vis DRS) for optical characterization. The 0.05 wt.% CuWO4-TiO2 catalyst was investigated for its photocatalytic activity over carbamazepine (CBZ), achieving a degradation of almost 100% after 2 h irradiation. A comparison with pure TiO2 prepared under those same conditions was made. The effect of pH, chemical scavengers, H2O2 as well as contaminant ion effects (anions, cations), and humic acid (HA) was investigated, and their related influences on the photocatalyst efficiency towards CBZ degradation highlighted accordingly.

scholarly journals Thermal Energy Storage Performance of Tetrabutylammonium Acrylate Hydrate as Phase Change Materials

2021 ◽  
Vol 11 (11) ◽  
pp. 4848
Author(s):  
Hitoshi Kiyokawa ◽  
Hiroki Tokutomi ◽  
Shinichi Ishida ◽  
Hiroaki Nishi ◽  
Ryo Ohmura
Keyword(s):  
Energy Storage ◽  
Heat Exchanger ◽  
Thermal Energy ◽  
Thermal Energy Storage ◽  
Phase Change Materials ◽  
Heat Storage ◽  
Solid Phase ◽  
Agitation Rate ◽  
Mechanical Agitation ◽  
External Forces

Kinetic characteristics of thermal energy storage (TES) using tetrabutylammonium acrylate (TBAAc) hydrate were experimentally evaluated for practical use as PCMs. Mechanical agitation or ultrasonic vibration was added to detach the hydrate adhesion on the heat exchanger, which could be a thermal resistance. The effect of the external forces also was evaluated by changing their rotation rate and frequency. When the agitation rate was 600 rpm, the system achieved TES density of 140 MJ/m3 in 2.9 hours. This value is comparable to the ideal performance of ice TES when its solid phase fraction is 45%. UA/V (U: thermal transfer coefficient, A: surface area of the heat exchange coil, V: volume of the TES medium) is known as an index of the ease of heat transfer in a heat exchanger. UA/V obtained in this study was comparable to that of other common heat exchangers, which means the equivalent performance would be available by setting the similar UA/V. In this study, we succeeded in obtaining practical data for heat storage by TBAAc hydrate. The data obtained in this study will be a great help for the practical application of hydrate heat storage in the future.

scholarly journals Development and Bio-Predictive Evaluation of Biopharmaceutical Properties of Sustained-Release Tablets with a Novel GPR40 Agonist for a First-in-Human Clinical Trial

Pharmaceutics ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 804
Author(s):  
Ewelina Juszczyk ◽  
Kamil Kisło ◽  
Paweł Żero ◽  
Ewa Tratkiewicz ◽  
Maciej Wieczorek ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Sustained Release ◽  
Development Strategy ◽  
Matrix Tablets ◽  
Matrix Tablet ◽  
Mechanical Agitation ◽  
Development Cycle ◽  
Dissolution Tests ◽  
Sustained Release Tablets ◽  
Biopharmaceutical Properties

Sustained-release (SR) formulations may appear advantageous in first-in-human (FIH) study of innovative medicines. The newly developed SR matrix tablets require prolonged maintenance of API concentration in plasma and should be reliably assessed for the risk of uncontrolled release of the drug. In the present study, we describe the development of a robust SR matrix tablet with a novel G-protein-coupled receptor 40 (GPR40) agonist for first-in-human studies and introduce a general workflow for the successful development of SR formulations for innovative APIs. The hydrophilic matrix tablets containing the labeled API dose of 5, 30, or 120 mg were evaluated with several methods: standard USP II dissolution, bio-predictive dissolution tests, and the texture and matrix formation analysis. The standard dissolution tests allowed preselection of the prototypes with the targeted dissolution rate, while the subsequent studies in physiologically relevant conditions revealed unwanted and potentially harmful effects, such as dose dumping under an increased mechanical agitation. The developed formulations were exceptionally robust toward the mechanical and physicochemical conditions of the bio-predictive tests and assured a comparable drug delivery rate regardless of the prandial state and dose labeled. In conclusion, the introduced development strategy, when implemented into the development cycle of SR formulations with innovative APIs, may allow not only to reduce the risk of formulation-related failure of phase I clinical trial but also effectively and timely provide safe and reliable medicines for patients in the trial and their further therapy.

scholarly journals Numerical Analysis on Performance of the Middle-Pressure Jet Grouting Method for Ground Improvement

Geosciences ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 313
Author(s):  
Shinya Inazumi ◽  
Sudip Shakya ◽  
Takahiro Komaki ◽  
Yasuharu Nakanishi
Keyword(s):  
Life Cycle ◽  
Comparative Analysis ◽  
Ground Improvement ◽  
Cement Slurry ◽  
Mechanical Agitation ◽  
High Quality ◽  
Jet Grouting ◽  
Computer Aided ◽  
Improvement Method ◽  
Cae System

This study focused on the middle-pressure jet grouting method, which has a complicated development mechanism for the columnar soil-improved body, with the aim of establishing a computer-aided engineering (CAE) system that can simulate the performance on a computer. Furthermore, in order to confirm the effect of middle-pressure jet grouting with mechanical agitation and mixing, a comparative analysis was performed with different jet pressures, the development situation was visualized, and the performance of this method was evaluated. The results of MPS-CAE as one of the CAE systems showed that the cement slurry jet ratio in the planned improvement range, including the periphery of the mixing blade, by the middle-pressure jet grouting together with the mechanical agitation and mixing was increased and a high quality columnar soil-improved body was obtained. It is expected that the introduction of CAE will contribute to the visualization of the ground, and that CAE will be an effective tool for the visual management of construction for ground improvement and the maintenance of improved grounds during the life cycle of the ground-improvement method.

scholarly journals Shear-Induced Amyloid Aggregation in the Brain: V. Are Alzheimer’s and Other Amyloid Diseases Initiated in the Lower Brain and Brainstem by Cerebrospinal Fluid Flow Stresses?

2020 ◽  
pp. 1-24
Author(s):  
Conrad N. Trumbore
Keyword(s):  
Cerebrospinal Fluid ◽  
Conformational Changes ◽  
Extensional Flow ◽  
Amyloid Β ◽  
High Energy ◽  
Mechanical Agitation ◽  
Cerebrospinal Fluid Flow ◽  
Pulse Waves ◽  
Amyloid Diseases ◽  
The Brain

Amyloid-β (Aβ) and tau oligomers have been identified as neurotoxic agents responsible for causing Alzheimer’s disease (AD). Clinical trials using Aβ and tau as targets have failed, giving rise to calls for new research approaches to combat AD. This paper provides such an approach. Most basic AD research has involved quiescent Aβ and tau solutions. However, studies involving laminar and extensional flow of proteins have demonstrated that mechanical agitation of proteins induces or accelerates protein aggregation. Recent MRI brain studies have revealed high energy, chaotic motion of cerebrospinal fluid (CSF) in lower brain and brainstem regions. These and studies showing CSF flow within the brain have shown that there are two energetic hot spots. These are within the third and fourth brain ventricles and in the neighborhood of the circle of Willis blood vessel region. These two regions are also the same locations as those of the earliest Aβ and tau AD pathology. In this paper, it is proposed that cardiac systolic pulse waves that emanate from the major brain arteries in the lower brain and brainstem regions and whose pulse waves drive CSF flows within the brain are responsible for initiating AD and possibly other amyloid diseases. It is further proposed that the triggering of these diseases comes about because of the strengthening of systolic pulses due to major artery hardening that generates intense CSF extensional flow stress. Such stress provides the activation energy needed to induce conformational changes of both Aβ and tau within the lower brain and brainstem region, producing unique neurotoxic oligomer molecule conformations that induce AD.

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