Novel Insights on the Functional Aspects of Quorum Sensing Systems and Its Applications in Medicine, Food Industry, and Agriculture

2019 ◽  
pp. 3-10
Author(s):  
Pallaval Veera Bramhachari
Keyword(s):  
Quorum Sensing ◽  
Food Industry ◽  
Sensing Systems ◽  
Functional Aspects

scholarly journals Parallel Quorum Sensing Systems Converge to Regulate Virulence in Vibrio cholerae

Cell ◽  
2002 ◽  
Vol 110 (3) ◽  
pp. 303-314 ◽  
Author(s):  
Melissa B. Miller ◽  
Karen Skorupski ◽  
Derrick H. Lenz ◽  
Ronald K. Taylor ◽  
Bonnie L. Bassler
Keyword(s):  
Quorum Sensing ◽  
Vibrio Cholerae ◽  
Sensing Systems

scholarly journals Interdependence of multi-drug efflux pumps and quorum sensing systems in Pseudomonas aeruginosa

2014 ◽  
Vol 21 ◽  
pp. 92
Author(s):  
K. Ganguly ◽  
J.L. Phillips ◽  
M.S. Wren ◽  
P.E. Pardington ◽  
S. Gnanakaran ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Quorum Sensing ◽  
Efflux Pumps ◽  
Drug Efflux ◽  
Sensing Systems ◽  
Drug Efflux Pumps

scholarly journals Electrochemical Biosensors in Food Safety: Challenges and Perspectives

Molecules ◽  
2021 ◽  
Vol 26 (10) ◽  
pp. 2940
Author(s):  
Antonella Curulli
Keyword(s):  
Food Industry ◽  
Electrochemical Sensors ◽  
Cost Effective ◽  
Electrochemical Biosensors ◽  
Food Chains ◽  
Sensing Systems ◽  
Highly Sensitive ◽  
Skilled Personnel ◽  
Recent Developments ◽  
Key Issues

Safety and quality are key issues for the food industry. Consequently, there is growing demand to preserve the food chain and products against substances toxic, harmful to human health, such as contaminants, allergens, toxins, or pathogens. For this reason, it is mandatory to develop highly sensitive, reliable, rapid, and cost-effective sensing systems/devices, such as electrochemical sensors/biosensors. Generally, conventional techniques are limited by long analyses, expensive and complex procedures, and skilled personnel. Therefore, developing performant electrochemical biosensors can significantly support the screening of food chains and products. Here, we report some of the recent developments in this area and analyze the contributions produced by electrochemical biosensors in food screening and their challenges.

scholarly journals Pseudomonas aeruginosa Quorum Sensing Systems as Drug Discovery Targets: Current Position and Future Perspectives

2018 ◽  
Vol 61 (23) ◽  
pp. 10385-10402 ◽  
Author(s):  
Fadi Soukarieh ◽  
Paul Williams ◽  
Michael J Stocks ◽  
Miguel Cámara
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Drug Discovery ◽  
Quorum Sensing ◽  
Future Perspectives ◽  
Current Position ◽  
Sensing Systems

scholarly journals Specificity and complexity in bacterial quorum-sensing systems

2016 ◽  
Vol 40 (5) ◽  
pp. 738-752 ◽  
Author(s):  
Lisa A. Hawver ◽  
Sarah A. Jung ◽  
Wai-Leung Ng
Keyword(s):  
Quorum Sensing ◽  
Sensing Systems ◽  
Bacterial Quorum Sensing ◽  
Bacterial Quorum

scholarly journals The Social Life of Aeromonas through Biofilm and Quorum Sensing Systems

2017 ◽  
Vol 8 ◽  
Author(s):  
Emilie Talagrand-Reboul ◽  
Estelle Jumas-Bilak ◽  
Brigitte Lamy
Keyword(s):  
Quorum Sensing ◽  
Social Life ◽  
Sensing Systems ◽  
The Social

Functional analysis of three AHL autoinducer synthase genes in Mesorhizobium loti reveals the important role of quorum sensing in symbiotic nodulation

2009 ◽  
Vol 55 (2) ◽  
pp. 210-214 ◽  
Author(s):  
Menghua Yang ◽  
Kejing Sun ◽  
Lei Zhou ◽  
Ruifu Yang ◽  
Zengtao Zhong ◽  
...  
Keyword(s):  
Quorum Sensing ◽  
Homoserine Lactone ◽  
Culture Conditions ◽  
Native Plant ◽  
Plant Host ◽  
Mesorhizobium Loti ◽  
Sensing Systems ◽  
Regulatory Circuits ◽  
Legume Symbiosis ◽  
Successful Establishment

One of the most important signal transduction pathways in bacteria, quorum sensing, is involved in many regulatory circuits in rhizobia, especially in the control of communication between rhizobia and their plant hosts. In this study, we identified 3 autoinducer synthase genes — mrlI1, mrlI2, and mrlI3 — in Mesorhizobium loti NZP 2213. We found that MrlI1 and MrlI2 could synthesize distinct N-acyl homoserine lactone (AHL) autoinducers in rich medium cultures, and the expression of mrlI1 was shown to be growth-phase-dependent. MrlI3 did not produce any detectable AHL molecules under the culture conditions tested. To investigate whether these AHL synthases affect nodulation, we examined the nodulation of AHL-deficient mutants on their native plant host Lotus corniculatus and found that the efficiency of nodulation of bacteria with mutations of any of these 3 synthase genes was reduced, suggesting that quorum sensing systems in M. loti may play an important role in successful establishment of rhizobium–legume symbiosis.

scholarly journals Bacterial Quorum Sensing and Food Industry

2011 ◽  
Vol 10 (3) ◽  
pp. 183-193 ◽  
Author(s):  
A. Jamuna Bai ◽  
V. Ravishankar Rai
Keyword(s):  
Quorum Sensing ◽  
Food Industry ◽  
Bacterial Quorum Sensing ◽  
Bacterial Quorum

scholarly journals The YebC Family Protein PA0964 Negatively Regulates the Pseudomonas aeruginosa Quinolone Signal System and Pyocyanin Production

2008 ◽  
Vol 190 (18) ◽  
pp. 6217-6227 ◽  
Author(s):  
Haihua Liang ◽  
Lingling Li ◽  
Zhaolin Dong ◽  
Michael G. Surette ◽  
Kangmin Duan
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Quorum Sensing ◽  
Virulence Factors ◽  
Response Regulator ◽  
Initial Study ◽  
Pfam Family ◽  
Swarming Motility ◽  
Sensing Systems ◽  
Family Protein ◽  
Pyocyanin Production

ABSTRACT Bacterial pathogenicity is often manifested by the expression of various cell-associated and secreted virulence factors, such as exoenzymes, protease, and toxins. In Pseudomonas aeruginosa, the expression of virulence genes is coordinately controlled by the global regulatory quorum-sensing systems, which includes the las and rhl systems as well as the Pseudomonas quinolone signal (PQS) system. Phenazine compounds are among the virulence factors under the control of both the rhl and PQS systems. In this study, regulation of the phzA1B1C1D1E1 (phzA1) operon, which is involved in phenazine synthesis, was investigated. In an initial study of inducing conditions, we observed that phzA1 was induced by subinhibitory concentrations of tetracycline. Screening of 13,000 mutants revealed 32 genes that altered phzA1 expression in the presence of subinhibitory tetracycline concentrations. Among them, the gene PA0964, designated pmpR ( p qsR-mediated P QS r egulator), has been identified as a novel regulator of the PQS system. It belongs to a large group of widespread conserved hypothetical proteins with unknown function, the YebC protein family (Pfam family DUF28). It negatively regulates the quorum-sensing response regulator pqsR of the PQS system by binding at its promoter region. Alongside phzA1 expression and phenazine and pyocyanin production, a set of virulence factors genes controlled by both rhl and the PQS were shown to be modulated by PmpR. Swarming motility and biofilm formation were also significantly affected. The results added another layer of regulation in the rather complex quorum-sensing systems in P. aeruginosa and demonstrated a clear functional clue for the YebC family proteins.

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