Lack of soluble carbonic anhydrase in aortic smooth muscle of the rabbit

1985 ◽  
Vol 405 (3) ◽  
pp. 234-236 ◽  
Author(s):  
M. M�hleisen ◽  
V. A. W. Kreye
Keyword(s):  
Smooth Muscle ◽  
Carbonic Anhydrase ◽  
Aortic Smooth Muscle ◽  
Soluble Carbonic Anhydrase

Neutrophil migration through in vitro interstitial matrix

1992 ◽  
Vol 50 (1) ◽  
pp. 894-895
Author(s):  
J. Roemer ◽  
S.R. Simon
Keyword(s):  
Extracellular Matrix ◽  
Smooth Muscle ◽  
Cell Migration ◽  
Smooth Muscle Cells ◽  
Inflammatory Cell ◽  
Neutrophil Migration ◽  
Culture Conditions ◽  
Aortic Smooth Muscle ◽  
Specific Culture

We are developing an in vitro interstitial extracellular matrix (ECM) system for study of inflammatory cell migration. Falcon brand Cyclopore membrane inserts of various pore sizes are used as a support substrate for production of ECM by R22 rat aortic smooth muscle cells. Under specific culture conditions these cells produce a highly insoluble matrix consisting of typical interstitial ECM components, i.e.: types I and III collagen, elastin, proteoglycans and fibronectin.

Sorghum Fermented by Aspergillus oryzae NK Enhances Inhibition of Vascular Inflammation in TNF-α-stimulated Human Aortic Smooth Muscle Cells

2018 ◽  
Vol 88 (5-6) ◽  
pp. 309-318
Author(s):  
Hae Seong Song ◽  
Jung-Eun Kwon ◽  
Hyun Jin Baek ◽  
Chang Won Kim ◽  
Hyelin Jeon ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Inflammatory Response ◽  
Smooth Muscle Cells ◽  
Adhesion Molecule ◽  
Vascular Inflammation ◽  
Muscle Cells ◽  
Aortic Smooth Muscle Cells ◽  
Aortic Smooth Muscle ◽  
Tnf Α ◽  
Cox 2

Abstract. Sorghum bicolor L. Moench is widely grown all over the world for food and feed. The effects of sorghum extracts on general inflammation have been previously studied, but its anti-vascular inflammatory effects are unknown. Therefore, this study investigated the anti-vascular inflammation effects of sorghum extract (SBE) and fermented extract of sorghum (fSBE) on human aortic smooth muscle cells (HASMCs). After the cytotoxicity test of the sorghum extract, a series of experiments were conducted. The inhibition effects of SBE and fSBE on the inflammatory response and adhesion molecule expression were measured using treatment with tumor necrosis factor-α (TNF-α), a crucial promoter for the development of atherosclerotic lesions, on HASMCs. After TNF-α (10 ng/mL) treatment for 2 h, then SBE and fSBE (100 and 200 μg/mL) were applied for 12h. Western blotting analysis showed that the expression of vascular cell adhesion molecule-1 (VCAM-1) (2.4-fold) and cyclooxygenase-2 (COX-2) (6.7-fold) decreased, and heme oxygenase-1 (HO-1) (3.5-fold) increased compared to the TNF-α control when treated with 200 μg/mL fSBE (P<0.05). In addition, the fSBE significantly increased the expression of HO-1 and significantly decreased the expression of VCAM-1 and COX-2 compared to the TNF-α control in mRNA level (P<0.05). These reasons of results might be due to the increased concentrations of procyanidin B1 (about 6-fold) and C1 (about 30-fold) produced through fermentation with Aspergillus oryzae NK for 48 h, at 37 °C. Overall, the results demonstrated that fSBE enhanced the inhibition of the inflammatory response and adherent molecule expression in HASMCs.

HMGA1– a central regulator of PPARgamma-mediated transrepression in human aortic smooth muscle cells

2009 ◽  
Vol 4 (S 01) ◽  
Author(s):  
M Bloch ◽  
A Foryst-Ludwig ◽  
T Unger ◽  
U Kintscher
Keyword(s):  
Smooth Muscle ◽  
Smooth Muscle Cells ◽  
Muscle Cells ◽  
Aortic Smooth Muscle Cells ◽  
Aortic Smooth Muscle

Effects of high glucose concentrations and epalrestat on sorbitol and myo-inositol metabolism in cultured rabbit aortic smooth muscle cells

Diabetes ◽  
1993 ◽  
Vol 42 (11) ◽  
pp. 1594-1600 ◽  
Author(s):  
F. Sakakibara ◽  
N. Hotta ◽  
N. Koh ◽  
N. Sakamoto
Keyword(s):  
Smooth Muscle ◽  
Smooth Muscle Cells ◽  
High Glucose ◽  
Muscle Cells ◽  
Aortic Smooth Muscle Cells ◽  
Aortic Smooth Muscle ◽  
Inositol Metabolism

Sodium Nitroprussid and Adenosine-Activated Potassium Channel in Aortic Smooth Muscle Isolated From Female Rats

2014 ◽  
Vol 2 (1) ◽  
pp. 1-7
Author(s):  
Omar Al-Habib ◽  
Chinar Muhammmad
Keyword(s):  
Smooth Muscle ◽  
Potassium Channel ◽  
Female Rats ◽  
Aortic Smooth Muscle

Calcifying Subpopulation of Bovine Aortic Smooth Muscle Cells Is Responsive to 17β-Estradiol

Circulation ◽  
1997 ◽  
Vol 95 (7) ◽  
pp. 1954-1960 ◽  
Author(s):  
Mihaela Balica ◽  
Kristina Boström ◽  
Victoria Shin ◽  
Kirsten Tillisch ◽  
Linda L. Demer
Keyword(s):  
Smooth Muscle ◽  
Smooth Muscle Cells ◽  
Muscle Cells ◽  
Aortic Smooth Muscle Cells ◽  
Aortic Smooth Muscle ◽  
17Β Estradiol
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