The displacement wave theory of blood vessel

1989 ◽  
Vol 10 (6) ◽  
pp. 487-493
Author(s):  
Yuan Fan ◽  
Wu Wang-yi
Author(s):  
Takeshi Tokunaga ◽  
Koji Mori ◽  
Hiroko Kadowaki ◽  
Takashi Saito

Abstract A gradient of a blood flow velocity on the surface of a blood vessel is one of the clinical medicine concerns from the view point of prevention of the arteriosclerosis. In previous study, we formulated a relationship between the pressure and a flow velocity based on the coupled wave theory of elastic pipes and Newtonian fluids [1]. In addition, a flow velocity distribution and a wall shear stress are estimated by using the blood pressure data, which are non-invasively obtained by the tonometry method. This method is quasi-analytical method to apply the coupled wave theory for industrial flow field inside steel pipes proposed by Urata [4] to blood vessel, and has the advantage of systematic estimator compared with the numerical calculation. However, the coupled wave theory has applied to the elastic pipes that were assumed to be infinitely long. In addition, a single wave was assumed to be dominant within the elastic pipes and the Newtonian fluids. Therefore, in order to apply various length vessels in clinical field, the boundary of the blood vessels that varies from site to site, and the natural vibration characteristics that depend on the boundary conditions, could not be reflected in the wall shear stress estimation. In general, in order to solve the forced vibration with the boundary condition, it is necessary to clarify natural frequency and natural mode as natural vibration characteristics of structure. In this study, we introduce the spring supported elastic pipes to the coupled wave theory and formulated a relationship between the natural vibration characteristics and the boundary conditions. In this proposed method, the spring-supported elastic pipe has a feature that can be treated as an arbitrary boundary condition of an artery by giving an appropriate spring coefficients. Therefore, it is easy to apply to various types of blood vessels clinically. By investigating the natural vibration characteristics of blood vessels that varies from site to site, it may be possible to clarify fluctuations of blood flow in response to blood pressure with some frequency-bands. In addition, natural angular frequencies and natural modes of the spring supported elastic pipes and the Newtonian fluids were estimated for general blood vessel based on the coupled wave theory. In the result, the natural angular frequencies and the natural modes that reflect the clinical vibration characteristics to some extent can be estimated. On the other hand, particular modes may not reflect boundary condition, and further examination of the relationship between natural vibration characteristics and boundary condition is needed.


1991 ◽  
Vol 7 (2) ◽  
pp. 97-103 ◽  
Author(s):  
Ding Guanghong ◽  
Liu Zhaorong

Author(s):  
T. M. Murad ◽  
E. von Haam

Pericytes are vascular satellites present around capillary blood vessels and small venules. They have been observed in almost every tissue of the body and are thought to be related to vascular smooth muscle cells. Morphologically pericytes have great similarity to vascular endothelial cells and also slightly resemble myoepithelial cells.The present study describes the ultrastructural morphology of pericytes in normal breast tissue and in benign tumor of the breast. The study showed that pericytes are ovoid or elongated cells separated from the endothelial cell of the capillary blood vessel by the basement membrane of endothelial cell. The nuclei of pericytes are often very distinctive. Although some are round, oval, or elongated, others show marked irregularity and infolding of the nuclear membrane. The cytoplasm shows mono-or bipolar extension in which the cytoplasmic organelles are located (Fig. 1). These cytoplasmic extensions embrace the capillary blood vessel incompletely. The plasma membrane exhibits multiple areas of focal condensation called hemidesmosomes (Fig. 2, arrow). A variable number of pinocytotic vesicles are frequently seen lining the outer plasma membrane. Normally pericytes are surrounded by a basement membrane which is found more consistently on the outer plasma membrane separating the pericytes from the stromal connective tissue.


1990 ◽  
Vol 64 (01) ◽  
pp. 091-096 ◽  
Author(s):  
W J Janssens ◽  
F J S Cools ◽  
L A M Hoskens ◽  
J M Van Nueten

SummaryRidogrel (6.3 × 10−6 to 10−4 M) inhibited contractions of isolated rat caudal arteries and rabbit femoral arteries caused by U-46619. The slope of an Arunlakshana-Schild plot (pA2-value: 3.4 × 10−6 M) on the caudal artery was slightly higher than one (1.14). This effect was maximal within}D min of incubation of the blood vessel with the compound and easily reversible. Ridogrel antagonised contractions of isolated rabbit femoral arteries caused by prostaglandin Fzo2α in the same concentration range. Ridogrel also inhibited contractions induced by aggregating rat platelets on isolated rat caudal arteries (itt the presence of ketanserin 4 × 10−7 M) and on isolated rabbit pulmonary and femoral arteries (in the absence of ketanserin). Ridogrel had no effect on Ca2+-induced contractions in depolarised isolated rabbit femoral arteries, and at 10−4 M antagonised serotonin-induced contractions in this blood vessel. Its effect on serotonin-induced contractions was statistically significant but very small on isolated rat caudal arteries. These observations indicate that ridogrel is an antagonist of prostaglandin endoperoxide/thromboxane A2 and prostaglandin F2α raCeptors on vascular smooth muscle.


1977 ◽  
Vol 38 (04) ◽  
pp. 0831-0849 ◽  
Author(s):  
Gwendolyn J. Stewart

SummaryBoth deep venous thrombosis and DIC are intermediate mechanisms of disease – both are a consequence of the deposition of fibrin-rich material in blood vessels some distance from the primary site of tissue destruction. The great difference in the sites of fibrin deposition may depend on the extent and site of activation of the clotting mechanism. DIC likely occurs in the fluid phase of the blood as a consequence of massive fibrin formation while thrombosis results from limited fibrin formation at the interface between blood and vessel wall. Leukocytes may be essential for attaching thrombi to the vessel wall in many places.


2020 ◽  
Author(s):  
Keyword(s):  

2018 ◽  
Vol 6 (9) ◽  
Author(s):  
DR.MATHEW GEORGE ◽  
DR.LINCY JOSEPH ◽  
MRS.DEEPTHI MATHEW ◽  
ALISHA MARIA SHAJI ◽  
BIJI JOSEPH ◽  
...  

Blood pressure is the force of blood pushing against blood vessel walls as the heart pumps out blood, and high blood pressure, also called hypertension, is an increase in the amount of force that blood places on blood vessels as it moves through the body. Factors that can increase this force include higher blood volume due to extra fluid in the blood and blood vessels that are narrow, stiff, or clogged(1). High blood pressure can damage blood vessels in the kidneys, reducing their ability to work properly. When the force of blood flow is high, blood vessels stretch so blood flows more easily. Eventually, this stretching scars and weakens blood vessels throughout the body, including those in the kidneys.


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